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GENE：CD70

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CD70
FullNmae CD70 molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11937
EnsembleID ENSG00000125726
Uniprot P32970

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CD70 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CD70 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CD70 GO:0002020,GO:0002456,GO:0005102,GO:0005125,GO:0005164,GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0007165,GO:0007267,GO:0019724,GO:0033209,GO:0042100,GO:0042102,GO:0070062,GO:0097191

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CD70 hsa:970 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CD70 CD27 17237405 19062317 26192618 interaction type N/A ACSN
CD40 CD70 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 26192618 7523569 8760829 9359474 interaction type N/A ACSN
CD40LG CD70 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 26192618 7523569 8760829 9359474 interaction type N/A ACSN
CD70 POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CD70 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CD70 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 CD70 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 CD70 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CD70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 CD70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CD70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CD70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CD70 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RFX1 CD70 21192791 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 CD70 25416803 28097098 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PLAA CD70 25348397 N/A physical interaction ComPPI
SCAMP1 CD70 25348397 N/A physical interaction ComPPI
GNL3L CD70 25348397 N/A physical interaction ComPPI
NUP85 CD70 25348397 N/A physical interaction ComPPI
HUS1 CD70 25348397 N/A physical interaction ComPPI
MAP2K2 CD70 25348397 N/A physical interaction ComPPI
RUFY1 CD70 25348397 N/A physical interaction ComPPI
NR2F2 CD70 25348397 N/A physical interaction ComPPI
RUFY2 CD70 25348397 N/A physical interaction ComPPI
ATM CD70 25348397 N/A physical interaction ComPPI
NUP98 CD70 25348397 N/A physical interaction ComPPI
TNFRSF17 CD70 25348397 N/A physical interaction ComPPI
IPO11 CD70 25348397 N/A physical interaction ComPPI
SEC14L1 CD70 25348397 N/A physical interaction ComPPI
CD27 CD70 14525934 15723067 25348397 7479974 8120384 8186199 8580829 9767422 9862673 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CD70 ELAVL1 25348397 N/A physical interaction ComPPI
CD70 KDM8 25348397 N/A physical interaction ComPPI
CD70 TNFRSF13B 25348397 N/A physical interaction ComPPI
CD70 TAMM41 25348397 N/A physical interaction ComPPI
CD70 FANCG 25348397 N/A physical interaction ComPPI
CD70 NR2C2 25348397 N/A physical interaction ComPPI
CD70 PDXDC1 25348397 N/A physical interaction ComPPI
CD70 UTP20 25348397 N/A physical interaction ComPPI
CD70 GPRC5B 25348397 N/A physical interaction ComPPI
CD70 TBC1D20 25348397 N/A physical interaction ComPPI
CD70 MAP2K3 25348397 N/A physical interaction ComPPI
CD70 PPTC7 25348397 N/A physical interaction ComPPI
CD70 TBRG4 25348397 N/A physical interaction ComPPI
CD70 METTL15 25348397 N/A physical interaction ComPPI
CD70 INTS2 25348397 N/A physical interaction ComPPI
CD70 ATRIP 25348397 N/A physical interaction ComPPI
CD70 ATL3 25348397 N/A physical interaction ComPPI
CD70 TTYH3 25348397 N/A physical interaction ComPPI
CD70 TNPO3 25348397 N/A physical interaction ComPPI
CD70 HEATR3 25348397 N/A physical interaction ComPPI
CD70 PDS5A 25348397 N/A physical interaction ComPPI
CD70 MIGA1 25348397 N/A physical interaction ComPPI
CD70 TIMELESS 25348397 N/A physical interaction ComPPI
CD70 DEPDC1 25348397 N/A physical interaction ComPPI
CD70 INTS4 25348397 N/A physical interaction ComPPI
CD70 INTS3 25348397 N/A physical interaction ComPPI
CD70 GLMN 25348397 N/A physical interaction ComPPI
CD70 SLC30A5 25348397 N/A physical interaction ComPPI
CD70 RANBP6 25348397 N/A physical interaction ComPPI
CD70 NOP9 25348397 N/A physical interaction ComPPI
CD70 IFRD1 25348397 N/A physical interaction ComPPI
CD70 CHPT1 25348397 N/A physical interaction ComPPI
CD70 PDS5B 25348397 N/A physical interaction ComPPI
CD70 GXYLT2 25348397 N/A physical interaction ComPPI
CD70 NR2F1 25348397 N/A physical interaction ComPPI
CD70 UBE4A 25348397 N/A physical interaction ComPPI
CD70 USP22 25348397 N/A physical interaction ComPPI
CD70 AARS2 25348397 N/A physical interaction ComPPI
CD70 COQ8B 25348397 N/A physical interaction ComPPI
CD70 NARS2 25348397 N/A physical interaction ComPPI
CD70 SLC31A1 25348397 N/A physical interaction ComPPI
CD70 TFB2M 25348397 N/A physical interaction ComPPI
CD70 EIF2B3 25348397 N/A physical interaction ComPPI
CD70 ADCY6 25348397 N/A physical interaction ComPPI
CD70 TTI1 25348397 N/A physical interaction ComPPI
CD70 DYM 25348397 N/A physical interaction ComPPI
CD70 HIP1R 25348397 N/A physical interaction ComPPI
CD70 ORC5 25348397 N/A physical interaction ComPPI
CD70 SPPL2B 25348397 N/A physical interaction ComPPI
CD70 EXOC6 25348397 N/A physical interaction ComPPI
CD70 INTS5 25348397 N/A physical interaction ComPPI
CD70 NOL11 25348397 N/A physical interaction ComPPI
CD70 GK 25348397 N/A physical interaction ComPPI
CD70 MDN1 25348397 N/A physical interaction ComPPI
CD70 UCKL1 25348397 N/A physical interaction ComPPI
CD70 STAG2 25348397 N/A physical interaction ComPPI
CD70 RBFA 25348397 N/A physical interaction ComPPI
CD70 NUP160 25348397 N/A physical interaction ComPPI
CD70 TUBB8 25348397 N/A physical interaction ComPPI
CD70 NUP107 25348397 N/A physical interaction ComPPI
CD70 ELOVL4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XPO4 CD70 25348397 N/A physical interaction ComPPI
XPO7 CD70 25348397 N/A physical interaction ComPPI
AGPAT5 CD70 25348397 N/A physical interaction ComPPI
DCUN1D5 CD70 25348397 N/A physical interaction ComPPI
CD70 CD27 12324477 15723067 21917027 26186194 26697006 27898060 7479974 8120384 8186199 8580829 9767422 9862673 stimulant N/A OmniPath

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