GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
CHCHD10
FullNmae
coiled-coil-helix-coiled-coil-helix domain containing 10
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:15559
EnsembleID
ENSG00000250479
Uniprot
Q8WYQ3
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
CHCHD10
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
CHCHD10
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
CHCHD10
GO:0003674,GO:0005515,GO:0005634,GO:0005739,GO:0005739,GO:0005758,GO:0006119,GO:0007005,GO:0007005,GO:0007005,GO:0030322,GO:0031930,GO:0051457,GO:0061617,GO:0065003,GO:0090144,GO:0099558,GO:1901030,GO:1903109,GO:1903852
KEGG Annotation:
GeneSymbol
GeneID
Pathway
Pathway Name
CHCHD10
hsa:400916
path:hsa05014
Amyotrophic lateral sclerosis - Homo sapiens (human)
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
PRDM14
CHCHD10
18971253
20953172
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
CTCF
CHCHD10
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00000AA464
CHCHD10
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000005481D
CHCHD10
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00000C85B2
CHCHD10
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS0000170D8B
CHCHD10
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00004AD450
CHCHD10
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000075BDA4
CHCHD10
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000075D15B
CHCHD10
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000070B1D
CHCHD10
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
CHCHD3
CHCHD10
24234451
25348397
26666268
physical association
blue native page
ComPPI,IntAct
CHCHD2
CHCHD10
24234451
25348397
27499296
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
ATP5PO
CHCHD10
25348397
N/A
physical interaction
ComPPI
SLC25A6
CHCHD10
25348397
N/A
physical interaction
ComPPI
COX5A
CHCHD10
25348397
N/A
physical interaction
ComPPI
U2AF2
CHCHD10
25348397
N/A
physical interaction
ComPPI
FAF1
CHCHD10
25348397
N/A
physical interaction
ComPPI
BAG1
CHCHD10
25348397
N/A
physical interaction
ComPPI
SREK1
CHCHD10
25348397
N/A
physical interaction
ComPPI
POLDIP2
CHCHD10
25348397
N/A
physical interaction
ComPPI
C1QBP
CHCHD10
25348397
N/A
physical interaction
ComPPI
PRRC2A
CHCHD10
25348397
N/A
physical interaction
ComPPI
ZFP91
CHCHD10
25348397
N/A
physical interaction
ComPPI
SLC16A1
CHCHD10
25348397
N/A
physical interaction
ComPPI
KLF13
CHCHD10
25348397
N/A
physical interaction
ComPPI
IMMT
CHCHD10
24234451
25348397
26666268
association,physical association
anti bait coimmunoprecipitation,physical interaction,blue native page,proximity ligation assay
ComPPI,IntAct
CLPX
CHCHD10
25348397
N/A
physical interaction
ComPPI
CMAS
CHCHD10
25348397
N/A
physical interaction
ComPPI
LUC7L
CHCHD10
25348397
N/A
physical interaction
ComPPI
THRAP3
CHCHD10
25348397
N/A
physical interaction
ComPPI
TIMM50
CHCHD10
25348397
N/A
physical interaction
ComPPI
RBM23
CHCHD10
25348397
N/A
physical interaction
ComPPI
BNC2
CHCHD10
25348397
N/A
physical interaction
ComPPI
RRP12
CHCHD10
25348397
N/A
physical interaction
ComPPI
ATP5F1C
CHCHD10
25348397
N/A
physical interaction
ComPPI
ECH1
CHCHD10
25348397
N/A
physical interaction
ComPPI
NDUFA5
CHCHD10
25348397
N/A
physical interaction
ComPPI
STOML2
CHCHD10
25348397
N/A
physical interaction
ComPPI
COX6C
CHCHD10
25348397
N/A
physical interaction
ComPPI
ATP5PD
CHCHD10
25348397
N/A
physical interaction
ComPPI
FIZ1
CHCHD10
25348397
N/A
physical interaction
ComPPI
ATP5MK
CHCHD10
25348397
N/A
physical interaction
ComPPI
CACTIN
CHCHD10
25348397
N/A
physical interaction
ComPPI
ATP5PB
CHCHD10
25348397
N/A
physical interaction
ComPPI
SFXN1
CHCHD10
25348397
N/A
physical interaction
ComPPI
DHX8
CHCHD10
25348397
N/A
physical interaction
ComPPI
RBM26
CHCHD10
25348397
N/A
physical interaction
ComPPI
OXA1L
CHCHD10
25348397
N/A
physical interaction
ComPPI
NDUFS3
CHCHD10
25348397
N/A
physical interaction
ComPPI
NDUFA8
CHCHD10
25348397
N/A
physical interaction
ComPPI
GHITM
CHCHD10
25348397
N/A
physical interaction
ComPPI
CHTOP
CHCHD10
25348397
N/A
physical interaction
ComPPI
PRRC2C
CHCHD10
25348397
N/A
physical interaction
ComPPI
MCCC1
CHCHD10
25348397
N/A
physical interaction
ComPPI
CARNMT1
CHCHD10
25348397
N/A
physical interaction
ComPPI
GLRX5
CHCHD10
25348397
N/A
physical interaction
ComPPI
RBM27
CHCHD10
25348397
N/A
physical interaction
ComPPI
PPM1K
CHCHD10
24234451
25348397
27499296
association
anti tag coimmunoprecipitation
ComPPI,IntAct
ZNF444
CHCHD10
25348397
N/A
physical interaction
ComPPI
Source
Target
Pmid
Interactiontype
Methods
Database
URS00009AE75B
CHCHD10
27087310
direct interaction,inhibition
N/A
NPInter
Visualization