Gene Information gene info

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GENE：CIB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CIB1
FullNmae calcium and integrin binding 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16920
EnsembleID ENSG00000185043
Uniprot Q99828

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CIB1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CIB1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CIB1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
CIB1 GO:0000287,GO:0001525,GO:0001933,GO:0001934,GO:0001954,GO:0002931,GO:0005509,GO:0005509,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005737,GO:0005737,GO:0005783,GO:0005794,GO:0005813,GO:0005886,GO:0006302,GO:0006915,GO:0006974,GO:0007026,GO:0007113,GO:0007155,GO:0007286,GO:0008284,GO:0008285,GO:0008427,GO:0010977,GO:0016020,GO:0016324,GO:0030027,GO:0030220,GO:0030291,GO:0030307,GO:0030335,GO:0030424,GO:0030426,GO:0031122,GO:0031267,GO:0031982,GO:0032433,GO:0032587,GO:0033630,GO:0038163,GO:0042127,GO:0042383,GO:0042383,GO:0043005,GO:0043025,GO:0043025,GO:0043066,GO:0043085,GO:0043204,GO:0043495,GO:0043495,GO:0044325,GO:0045653,GO:0048471,GO:0051092,GO:0051301,GO:0051302,GO:0051898,GO:0070062,GO:0070374,GO:0070886,GO:0070886,GO:0071356,GO:0071363,GO:0071363,GO:0071902,GO:0071944,GO:0090050,GO:0090314,GO:0097191,GO:1900026,GO:1903078,GO:1903078,GO:1990090,GO:2000256

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TERT CIB1 15190070 23180781 physical association two hybrid,pull down InnateDB
PRKDC CIB1 15190070 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CIB1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 CIB1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CIB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 CIB1 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PRKD2 CIB1 22135298 phosphorylation N/A PhosphoSite
CIB1 MAP3K5 25361965 interaction type N/A PTMCode2
MAP3K5 CIB1 25361965 interaction type N/A PTMCode2
CIB1 PLK3 25361965 interaction type N/A PTMCode2
PLK3 CIB1 25361965 interaction type N/A PTMCode2
CIB1 WAS 25361965 interaction type N/A PTMCode2
WAS CIB1 25361965 interaction type N/A PTMCode2
ITGA2B CIB1 25361965 interaction type N/A PTMCode2
CIB1 ITGA2B 25361965 interaction type N/A PTMCode2
PLK2 CIB1 25361965 interaction type N/A PTMCode2
CIB1 PLK2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
WASL CIB1 16582881 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,surface plasmon resonance ComPPI,IntAct
WAS CIB1 14525934 16582881 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
NRIP1 CIB1 25348397 N/A physical interaction ComPPI
PAK1 CIB1 16061695 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PRKDC CIB1 14525934 15190070 25348397 9372844 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
NBR1 CIB1 25348397 N/A two hybrid,physical interaction,in vitro ComPPI
CIB1 PSEN2 10366599 14525934 24234451 25348397 colocalization,physical association two hybrid,experimental interaction detection,pull down,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CIB1 RAC3 11756406 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
CIB1 ITGA2B 10358085 14525934 20034469 25348397 27898060 9030514 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
CIB1 UBR5 12011095 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
CIB1 FEZ1 11856312 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
CIB1 PAX3 11997098 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
CIB1 EXOSC10 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CIB1 PSEN1 10366599 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
CIB1 TERT 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
CIB1 PTK2 25348397 N/A physical interaction ComPPI
CIB1 CDK4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CIB1 AURKB 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CIB1 ZDHHC17 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CIB1 UPK1A 25348397 N/A physical interaction ComPPI
CIB1 TMC7 25348397 N/A physical interaction ComPPI
CIB1 ITGB3 25348397 N/A physical interaction ComPPI
CIB1 ITGA5 25348397 N/A physical interaction ComPPI
CIB1 MAP3K5 19805025 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
CIB1 ITGA2 16582881 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CIB1 NME4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 CD27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 CALCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 CEACAM6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 FUCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 LSS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 SCAF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 ONECUT3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 SSX7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 TSGA10IP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 ZBTB49 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CIB1 TMEM95 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLK3 CIB1 10523297 11039900 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
PLK2 CIB1 10523297 12651910 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
IFI6 CIB1 14525934 15685448 N/A two hybrid HPRD
CRY2 CIB1 18988809 21037589 22139370 22739826 22922268 24780222 27898060 N/A N/A OmniPath
CIB1 PAK1 16061695 27898060 stimulant N/A OmniPath
PRKD2 CIB1 23503467 27898060 N/A N/A OmniPath

Visualization










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