GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
COA8
FullNmae
cytochrome c oxidase assembly factor 8
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:20492
EnsembleID
ENSG00000256053
Uniprot
Q96IL0
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
COA8
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
COA8
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
COA8
GO:0000302,GO:0005739,GO:0005739,GO:0033617,GO:0033617,GO:0050821,GO:0097193,GO:0099617,GO:1903427,GO:1904960,GO:1904960
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
COA8
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
RUNX1
COA8
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00003D5391
COA8
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00001597DC
COA8
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000043D2C1
COA8
22100165
25416803
mrna cleavage,inhibition
clip
TarBase
URS000008AA34
COA8
22100165
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000118224
COA8
22100165
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002C02E4
COA8
22100165
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075AEA5
COA8
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00003758F0
COA8
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001F5B39
COA8
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002C7B2B
COA8
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000EED18
COA8
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000013E79D
COA8
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000016FD1A
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000021D7C8
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075C1E1
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000075D2F5
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00001FC26E
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000411752
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000EEF5F
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000005CE28
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00000753AD
COA8
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
DPY30
COA8
25348397
N/A
physical interaction
ComPPI
BAG3
COA8
25348397
N/A
physical interaction
ComPPI
KIF5B
COA8
25348397
N/A
physical interaction
ComPPI
YWHAG
COA8
25348397
N/A
physical interaction
ComPPI
SKP1
COA8
25348397
N/A
physical interaction
ComPPI
KRT31
COA8
25348397
N/A
physical interaction
ComPPI
CSNK1D
COA8
25348397
N/A
physical interaction
ComPPI
LDLRAP1
COA8
25348397
N/A
physical interaction
ComPPI
CBY1
COA8
25348397
N/A
physical interaction
ComPPI
TLE3
COA8
25348397
N/A
physical interaction
ComPPI
EZH2
COA8
25348397
N/A
physical interaction
ComPPI
USP7
COA8
25348397
N/A
physical interaction
ComPPI
PIAS1
COA8
25348397
N/A
physical interaction
ComPPI
YWHAB
COA8
25348397
N/A
physical interaction
ComPPI
YWHAZ
COA8
25348397
N/A
physical interaction
ComPPI
NTRK1
COA8
25348397
N/A
physical interaction
ComPPI
COPB1
COA8
25348397
N/A
physical interaction
ComPPI
DIAPH1
COA8
25348397
N/A
physical interaction
ComPPI
MAPK8IP3
COA8
25348397
N/A
physical interaction
ComPPI
CLK1
COA8
25348397
N/A
physical interaction
ComPPI
TRIP6
COA8
25348397
N/A
physical interaction
ComPPI
MAPK6
COA8
25348397
N/A
physical interaction
ComPPI
RAP1B
COA8
25348397
N/A
physical interaction
ComPPI
EXOC3
COA8
25348397
N/A
physical interaction
ComPPI
SNAPIN
COA8
25348397
N/A
physical interaction
ComPPI
SFN
COA8
25348397
N/A
physical interaction
ComPPI
YWHAE
COA8
25348397
N/A
physical interaction
ComPPI
USF1
COA8
25348397
N/A
physical interaction
ComPPI
NOLC1
COA8
25348397
N/A
physical interaction
ComPPI
HSPB1
COA8
25348397
N/A
physical interaction
ComPPI
TRPC4AP
COA8
25348397
N/A
physical interaction
ComPPI
KIF5C
COA8
25348397
N/A
physical interaction
ComPPI
SNCA
COA8
25348397
N/A
physical interaction
ComPPI
TRIM25
COA8
25348397
N/A
physical interaction
ComPPI
ARCN1
COA8
25348397
N/A
physical interaction
ComPPI
RAB11FIP2
COA8
25348397
N/A
physical interaction
ComPPI
ORC3
COA8
25348397
N/A
physical interaction
ComPPI
KLC3
COA8
25348397
N/A
physical interaction
ComPPI
DTNBP1
COA8
25348397
N/A
physical interaction
ComPPI
KIF2B
COA8
25348397
N/A
physical interaction
ComPPI
SORT1
COA8
25348397
N/A
physical interaction
ComPPI
BNIP2
COA8
25348397
N/A
physical interaction
ComPPI
PRKAG3
COA8
25348397
N/A
physical interaction
ComPPI
COPZ1
COA8
25348397
N/A
physical interaction
ComPPI
POLR2C
COA8
25348397
N/A
physical interaction
ComPPI
ARHGAP17
COA8
25348397
N/A
physical interaction
ComPPI
KLC2
COA8
25348397
N/A
physical interaction
ComPPI
CEP44
COA8
25348397
N/A
physical interaction
ComPPI
KLC4
COA8
25348397
N/A
physical interaction
ComPPI
OFD1
COA8
25348397
N/A
physical interaction
ComPPI
KPTN
COA8
25348397
N/A
physical interaction
ComPPI
MYCL
COA8
25348397
N/A
physical interaction
ComPPI
APP
COA8
25348397
N/A
physical interaction
ComPPI
COA8
RABEP2
25348397
N/A
physical interaction
ComPPI
AZIN1
COA8
25348397
N/A
physical interaction
ComPPI
Visualization