GENE:DAP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DAP |
| FullNmae | death associated protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2672 |
| EnsembleID | ENSG00000112977 |
| Uniprot | P51397 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DAP | autophagy | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| DAP | autophagy | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
| DAP | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| DAP | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DAP | GO:0006417,GO:0006914,GO:0006915,GO:0006919,GO:0010507,GO:0010507,GO:0032088,GO:0034198,GO:0034198,GO:0045892,GO:0070513,GO:0070513,GO:0097190,GO:0097190 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DAP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | DAP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | DAP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | DAP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | DAP | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | DAP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MTOR | DAP | 22135298 | phosphorylation | N/A | PhosphoSite |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SETDB1 | DAP | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| HNRNPL | DAP | 25348397 | N/A | physical interaction | ComPPI |
| PCNA | DAP | 27898060 9705499 | N/A | N/A | OmniPath |
| MTOR | DAP | 16602700 17081983 18669648 20537536 27898060 | stimulant | N/A | OmniPath |
