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GENE：DPF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DPF2
FullNmae double PHD fingers 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9964
EnsembleID ENSG00000133884
Uniprot Q92785

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DPF2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DPF2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
DPF2 GO:0000122,GO:0000785,GO:0000785,GO:0000785,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0005813,GO:0005829,GO:0006338,GO:0006357,GO:0006915,GO:0007399,GO:0016514,GO:0030071,GO:0043231,GO:0046872,GO:0062072,GO:0070316,GO:0070577,GO:0071565,GO:0097190,GO:1902459,GO:1905454,GO:2000045,GO:2000781,GO:2000819

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DPF2 hsa:5977 path:hsa03082 ATP-dependent chromatin remodeling - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BMI1 DPF2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DPF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DPF2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DPF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 DPF2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 DPF2 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00004AC389 DPF2 25074381 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00003E226A DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000453664 DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EBD4B DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA DPF2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 DPF2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
SNW1 DPF2 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
SMARCE1 DPF2 25348397 N/A physical interaction ComPPI
TXNDC12 DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LDOC1 DPF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SMARCC1 DPF2 22334708 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TP53BP1 DPF2 25348397 N/A physical interaction ComPPI
GABARAPL2 DPF2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BMI1 DPF2 25348397 N/A physical interaction ComPPI
H2BC4 DPF2 25348397 N/A physical interaction ComPPI
RINT1 DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DDIT4L DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZNF212 DPF2 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PICK1 DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
REL DPF2 25348397 N/A physical interaction ComPPI
NFATC1 DPF2 25348397 N/A physical interaction ComPPI
JUN DPF2 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AR DPF2 25348397 N/A physical interaction ComPPI
SMARCD1 DPF2 25348397 N/A physical interaction ComPPI
COPS5 DPF2 25348397 N/A physical interaction ComPPI
FHL2 DPF2 18255255 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CUL3 DPF2 25348397 N/A physical interaction ComPPI
RUBCN DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMARCA4 DPF2 22334708 23540691 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARID1B DPF2 25348397 N/A physical interaction ComPPI
NFATC2 DPF2 25348397 N/A physical interaction ComPPI
RELA DPF2 22334708 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCB1 DPF2 24234451 25348397 30108113 association pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UPF2 DPF2 25348397 N/A physical interaction ComPPI
H3-4 DPF2 25348397 N/A physical interaction ComPPI
BANF1 DPF2 25348397 N/A physical interaction ComPPI
RNF2 DPF2 25348397 N/A physical interaction ComPPI
YAP1 DPF2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NCSTN DPF2 25348397 N/A physical interaction ComPPI
ACTL6A DPF2 25348397 N/A physical interaction ComPPI
ID1 DPF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
H3C1 DPF2 25348397 N/A physical interaction ComPPI
PDCD6 DPF2 25348397 N/A physical interaction ComPPI
SS18 DPF2 23540691 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTL6B DPF2 25348397 N/A physical interaction ComPPI
NFKB1 DPF2 25348397 N/A physical interaction ComPPI
NFKB2 DPF2 25348397 N/A physical interaction ComPPI
SS18L1 DPF2 25348397 N/A physical interaction ComPPI
SMARCD3 DPF2 25348397 N/A physical interaction ComPPI
SMARCC2 DPF2 25348397 N/A physical interaction ComPPI
SMARCD2 DPF2 25348397 N/A physical interaction ComPPI
EPAS1 DPF2 25348397 N/A physical interaction ComPPI
CDK11B DPF2 25348397 N/A physical interaction ComPPI
ARID1A DPF2 25348397 N/A physical interaction ComPPI
LNX1 DPF2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UGGT1 DPF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK11A DPF2 25348397 N/A physical interaction ComPPI
RELB DPF2 14525934 14743216 24234451 25348397 physical association experimental interaction detection,physical interaction,in vitro,tandem affinity purification ComPPI,HPRD,IntAct
ZNF655 DPF2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL7A DPF2 25348397 N/A physical interaction ComPPI
DPF2 BCL7C 25348397 N/A physical interaction ComPPI
DPF2 SMARCA2 22334708 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DPF2 DDX18 25348397 N/A physical interaction ComPPI
DPF2 BCL7B 25348397 N/A physical interaction ComPPI
DPF2 H2BC11 25348397 N/A physical interaction ComPPI
DPF2 HMBOX1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DPF2 NAF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DPF2 TTC23L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DPF2 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DPF2 GOLGA6L9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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