Gene Information gene info

  1. Home

GENE：EDA2R

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EDA2R
FullNmae ectodysplasin A2 receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17756
EnsembleID ENSG00000131080
Uniprot Q9HAV5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EDA2R apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EDA2R apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
EDA2R GO:0005031,GO:0005515,GO:0005886,GO:0005886,GO:0008544,GO:0010668,GO:0016020,GO:0033209,GO:0038023,GO:0038023,GO:0043123,GO:0046330,GO:0046330,GO:0051092,GO:0072332

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EDA2R hsa:60401 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
EDA2R hsa:60401 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TRAF6 EDA2R 12060722 12270937 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB

Source Target Pmid Interactiontype Methods Database
FADD EDA2R 20005715 interaction type N/A PSP
TRAF3 EDA2R 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
YBX1 EDA2R 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 EDA2R 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EDA2R 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 EDA2R 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE EDA2R 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000011A030 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000458AD2 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001B968D EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000383DF4 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000019D79B EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000364FEF EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001799A3 EDA2R 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 EDA2R 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F EDA2R 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CF056 EDA2R 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000025EABA EDA2R 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SGTA EDA2R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AGR3 EDA2R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TK1 EDA2R 25348397 N/A physical interaction ComPPI
TRAF6 EDA2R 15280356 24234451 25348397 physical association coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct
JAGN1 EDA2R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ATP6V0C EDA2R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CASP8 EDA2R 25348397 N/A coimmunoprecipitation,in vitro ComPPI
TRAF3 EDA2R 15280356 24234451 25348397 physical association coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct
FADD EDA2R 15280356 24234451 25348397 physical association coimmunoprecipitation,in vitro ComPPI,IntAct
TRAF1 EDA2R 25348397 N/A physical interaction ComPPI
TRAF2 EDA2R 25348397 N/A physical interaction ComPPI
CEBPE EDA2R 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CASP10 EDA2R 25348397 N/A coimmunoprecipitation ComPPI
ATP2B4 EDA2R 25348397 N/A physical interaction ComPPI
EDA EDA2R 25348397 N/A in vitro ComPPI
EDA2R C1QB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EDA2R HSDL1 25348397 N/A physical interaction ComPPI
EDA2R ICAM1 25348397 N/A physical interaction ComPPI
EDA2R GIMAP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EDA2R TMEM262 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EDA2R STRIT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NKG7 EDA2R 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EDA2R TRAF6 12060722 12270937 15280356 26186194 27898060 N/A N/A OmniPath
TRAF6 EDA2R 12060722 12270937 15280356 26186194 27898060 N/A N/A OmniPath
EDA EDA2R 11039935 12084975 12270937 27898060 stimulant N/A OmniPath

Visualization










  Return