GENE：ELL3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ELL3 |
| FullNmae | elongation factor for RNA polymerase II 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:23113 |
| EnsembleID | ENSG00000128886 |
| Uniprot | Q9HB65 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ELL3 | parthanatos | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ELL3 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ELL3 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ELL3 | GO:0000987,GO:0000987,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005694,GO:0005730,GO:0005829,GO:0006354,GO:0006366,GO:0006368,GO:0007283,GO:0008023,GO:0008023,GO:0008023,GO:0010717,GO:0016607,GO:0030054,GO:0032786,GO:0032968,GO:0042771,GO:0042795,GO:0042795,GO:0045944,GO:0048863,GO:0050769,GO:0061351,GO:0072089,GO:1902166,GO:2000179,GO:2000648 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ELL3 | hsa:80237 | path:hsa03250 | Viral life cycle - HIV-1 - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FTH1 | ELL3 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ADD3 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| AFF1 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| CCNT1 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| ELL | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| SIRT1 | ELL3 | 19343720 24234451 25348397 | physical association | pull down,physical interaction | ComPPI,IntAct |
| CDK9 | ELL3 | 21729782 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| EAF2 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| EAF1 | ELL3 | 21729782 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| AFF4 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| MLLT1 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| CDK14 | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| PIP4K2A | ELL3 | 25348397 | N/A | physical interaction | ComPPI |
| ELL3 | TP53 | 25348397 | N/A | physical interaction | ComPPI |