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GENE：ERBB3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ERBB3
FullNmae erb-b2 receptor tyrosine kinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3431
EnsembleID ENSG00000065361
Uniprot P21860

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ERBB3 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ERBB3 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ERBB3 GO:0003197,GO:0004888,GO:0005515,GO:0005524,GO:0005615,GO:0005886,GO:0007162,GO:0007165,GO:0007169,GO:0007169,GO:0007275,GO:0007422,GO:0007507,GO:0008284,GO:0009925,GO:0009968,GO:0010628,GO:0014037,GO:0016310,GO:0016323,GO:0016324,GO:0016328,GO:0019838,GO:0019838,GO:0021545,GO:0022008,GO:0030296,GO:0031625,GO:0033674,GO:0038131,GO:0038132,GO:0038132,GO:0038133,GO:0038143,GO:0042060,GO:0042127,GO:0042802,GO:0043066,GO:0043125,GO:0043235,GO:0043235,GO:0043235,GO:0043491,GO:0043524,GO:0046982,GO:0051048,GO:0051402,GO:0051897,GO:0055025,GO:0061098,GO:0070886,GO:0097049,GO:0097192,GO:2000672

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ERBB3 hsa:2065 path:hsa01521 EGFR tyrosine kinase inhibitor resistance - Homo sapiens (human)
ERBB3 hsa:2065 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
ERBB3 hsa:2065 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
ERBB3 hsa:2065 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
ERBB3 hsa:2065 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
ERBB3 hsa:2065 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
ERBB3 hsa:2065 path:hsa05206 MicroRNAs in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ERBB2 ERBB3 12648465 23331499 stimulation N/A SignaLink,SignaLink
LRIG1 ERBB3 16123311 23331499 stimulation N/A SignaLink,SignaLink
ERBB3 PIK3R1 10383151 11546794 18988627 21071413 23331499 stimulation N/A SignaLink,SignaLink
NRG2 ERBB3 23331499 9168114 9168115 stimulation N/A SignaLink
NRG1 ERBB3 11555649 23331499 9275162 stimulation N/A SignaLink
AR ERBB3 15542423 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
GATA2 ERBB3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ERBB3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A ERBB3 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 ERBB3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ERBB3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR ERBB3 21741601 trascriptional regulation,stimulation inferred by curator TFlink
TWIST1 ERBB3 19051271 trascriptional regulation,stimulation inferred by curator TFlink
TWIST2 ERBB3 19051271 trascriptional regulation,stimulation inferred by curator TFlink
YBX1 ERBB3 19648825 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001F0C23 ERBB3 N/A 17110380 20864407 \N rna interference,inhibition array technology,experimental interaction detection,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000016914 ERBB3 19238171 19276373 20065103 20864407 \N rna interference,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000096022 ERBB3 22484852 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001F0C23 ERBB3 17110380 18927107 20864407 23519125 25416803 mrna cleavage,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miR2Disease,TarBase
URS0000016914 ERBB3 19238171 19276373 20065103 20864407 23519125 25416803 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000096022 ERBB3 22484852 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000008A99 ERBB3 22942087 25248370 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000CBE63 ERBB3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004F507C ERBB3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C ERBB3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000072B4C8 ERBB3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 ERBB3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B ERBB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0BB4 ERBB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A122A ERBB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC ERBB3 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC ERBB3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003538C1 ERBB3 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004ACAAA ERBB3 25416803 26043902 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS000042619A ERBB3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIK3CA ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 PIK3CA 25361965 interaction type N/A PTMCode2
ERBB3 ERBB2 25361965 interaction type N/A PTMCode2
ERBB2 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 LRIG1 25361965 interaction type N/A PTMCode2
LRIG1 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 PIK3R1 25361965 interaction type N/A PTMCode2
PIK3R1 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 EGFR 25361965 interaction type N/A PTMCode2
EGFR ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 PA2G4 25361965 interaction type N/A PTMCode2
PA2G4 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 GRB2 25361965 interaction type N/A PTMCode2
GRB2 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 ERBB4 25361965 interaction type N/A PTMCode2
ERBB4 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 RNF41 25361965 interaction type N/A PTMCode2
RNF41 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 ARHGEF7 25361965 interaction type N/A PTMCode2
ARHGEF7 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 JAK2 25361965 interaction type N/A PTMCode2
JAK2 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 SOS1 25361965 interaction type N/A PTMCode2
SOS1 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 RGS4 25361965 interaction type N/A PTMCode2
RGS4 ERBB3 25361965 interaction type N/A PTMCode2
ERBB3 SHC1 25361965 interaction type N/A PTMCode2
SHC1 ERBB3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
NCK2 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PIK3R2 ERBB3 14525934 16273093 16729043 24189400 24234451 25348397 association,physical association experimental interaction detection,protein array,pull down,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
HSPA8 ERBB3 25348397 N/A physical interaction ComPPI
RPN1 ERBB3 25348397 N/A physical interaction ComPPI
HBD ERBB3 25348397 N/A physical interaction ComPPI
ACTG1 ERBB3 25348397 N/A physical interaction ComPPI
TUBB ERBB3 25348397 N/A physical interaction ComPPI
PTPRH ERBB3 25348397 N/A physical interaction ComPPI
ACTB ERBB3 25348397 N/A physical interaction ComPPI
PTPN6 ERBB3 25348397 N/A physical interaction ComPPI
SLC25A6 ERBB3 25348397 N/A physical interaction ComPPI
HBA1 ERBB3 25348397 N/A physical interaction ComPPI
DPPA4 ERBB3 25348397 N/A physical interaction ComPPI
HSP90AB1 ERBB3 22939624 24189400 24234451 25348397 association,physical association physical interaction,tandem affinity purification,luminescence based mammalian interactome mapping ComPPI,IntAct
TUFM ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CRK ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
HNRNPH2 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
UQCRH ERBB3 25348397 N/A physical interaction ComPPI
RIN1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
GRB7 ERBB3 14525934 16273093 24189400 24234451 25348397 9516479 association experimental interaction detection,protein array,physical interaction,competition binding,tandem affinity purification ComPPI,HPRD,IntAct
ERBB2 ERBB3 10572067 10799311 11173924 14525934 16843263 17148612 17426253 19411071 20227043 21075308 21203579 21278786 22733765 22806884 23436906 23680147 23688700 23866081 24234451 24557338 25241761 25326665 25348397 7538656 7592681 association,physical association anti bait coimmunoprecipitation,beta galactosidase complementation,cosedimentation in solution,cross-linking study,protein cross-linking with a bifunctional reagent,experimental interaction detection,pull down,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
CD82 ERBB3 14525934 14576349 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
VAV1 ERBB3 25348397 N/A physical interaction ComPPI
SYK ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
IL6ST ERBB3 11821958 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PTK2B ERBB3 14525934 15499613 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
VAV2 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
ERBB4 ERBB3 10572067 14525934 20227043 24234451 25348397 7689552 physical association anti bait coimmunoprecipitation,experimental interaction detection ComPPI,HPRD,IntAct
PIK3R1 ERBB3 10383151 10572067 11546794 14525934 16273093 20007781 20227043 21075308 21278786 22439932 24189400 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,protein array,physical interaction,tandem affinity purification,two hybrid ComPPI,HPRD,IntAct
PTPN11 ERBB3 25348397 N/A physical interaction ComPPI
SRC ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
CRKL ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SH2B3 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
VAV3 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SHC1 ERBB3 14525934 16273093 16729043 24189400 24234451 25348397 9694850 association,physical association experimental interaction detection,protein array,pull down,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
NCK1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
GRB2 ERBB3 11173924 14525934 16729043 24189400 24234451 24658140 25348397 association,physical association experimental interaction detection,pull down,ubiquitin reconstruction,physical interaction,tandem affinity purification ComPPI,HPRD,IntAct
MTMR10 ERBB3 25348397 N/A physical interaction ComPPI
ZAP70 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
ITK ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
HBG2 ERBB3 25348397 N/A physical interaction ComPPI
TUBA1B ERBB3 25348397 N/A physical interaction ComPPI
PIK3CB ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HGS ERBB3 25348397 N/A physical interaction ComPPI
PPM1A ERBB3 25348397 N/A physical interaction ComPPI
PIK3CA ERBB3 19411071 24189400 24234451 25348397 association,physical association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PIK3R3 ERBB3 16273093 24189400 24234451 25348397 association protein array,physical interaction,tandem affinity purification ComPPI,IntAct
RPS27A ERBB3 25348397 N/A physical interaction ComPPI
HSP90AA1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DAB1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
CANX ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDH1 ERBB3 25348397 N/A physical interaction ComPPI
RGS4 ERBB3 12840049 14525934 25348397 N/A experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD
TNS2 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
AP1M2 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
L1CAM ERBB3 25348397 N/A physical interaction ComPPI
HSPA5 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HSPA1A ERBB3 25348397 N/A physical interaction ComPPI
HSPA1B ERBB3 25348397 N/A physical interaction ComPPI
PTPN7 ERBB3 25348397 N/A physical interaction ComPPI
FER ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
TUBA4A ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
C1QBP ERBB3 25348397 N/A physical interaction ComPPI
PTPRR ERBB3 25348397 N/A physical interaction ComPPI
PTPN12 ERBB3 25348397 N/A physical interaction ComPPI
PA2G4 ERBB3 10682683 11325528 14525934 15583694 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid ComPPI,HPRD,IntAct
NDRG1 ERBB3 25348397 N/A physical interaction ComPPI
CSK ERBB3 16729043 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
EPN1 ERBB3 25348397 N/A physical interaction ComPPI
NEDD4L ERBB3 25348397 N/A physical interaction ComPPI
HNRNPA2B1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MET ERBB3 24234451 25326665 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 ERBB3 25348397 N/A physical interaction ComPPI
EGF ERBB3 12093292 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
EGFR ERBB3 10527633 10572067 14525934 17148612 21278786 22439932 23436906 23866081 24189400 24234451 25348397 association,physical association anti bait coimmunoprecipitation,beta galactosidase complementation,protein cross-linking with a bifunctional reagent,experimental interaction detection,physical interaction,tandem affinity purification,proximity ligation assay ComPPI,HPRD,IntAct
FGFR1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
RASA1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
DUSP14 ERBB3 25348397 N/A physical interaction ComPPI
JAK3 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
JAK2 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
ANXA2 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
SH2D1A ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
HDAC6 ERBB3 20029029 24234451 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
TXK ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PTK6 ERBB3 11114724 14525934 16273093 24234451 25348397 N/A experimental interaction detection,protein array,physical interaction ComPPI,HPRD,IntAct
NRG2 ERBB3 14525934 25348397 9168114 9168115 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PTEN ERBB3 25348397 N/A physical interaction ComPPI
SHC3 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
EIF1AX ERBB3 25348397 N/A physical interaction ComPPI
B2M ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LRPPRC ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NEDD4 ERBB3 25348397 N/A physical interaction ComPPI
PPM1B ERBB3 25348397 N/A physical interaction ComPPI
CDC37 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DNAJB11 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HNRNPF ERBB3 25348397 N/A physical interaction ComPPI
HNRNPH1 ERBB3 25348397 N/A physical interaction ComPPI
HLA-A ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
HLA-B ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MASP1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RNF41 ERBB3 12411582 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
SRPK2 ERBB3 25348397 N/A physical interaction ComPPI
SSR1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
RAE1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CDC25C ERBB3 25348397 N/A physical interaction ComPPI
AKT1 ERBB3 25348397 N/A physical interaction ComPPI
RPL23 ERBB3 25348397 N/A physical interaction ComPPI
S100A10 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ILKAP ERBB3 25348397 N/A physical interaction ComPPI
DNAJA1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DUSP19 ERBB3 25348397 N/A physical interaction ComPPI
PPM1F ERBB3 25348397 N/A physical interaction ComPPI
HNRNPAB ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
CHN2 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
PHLDA1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MTMR2 ERBB3 25348397 N/A physical interaction ComPPI
BCAR3 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
EGR1 ERBB3 25348397 N/A physical interaction ComPPI
CSPG5 ERBB3 25348397 N/A physical interaction ComPPI
STYX ERBB3 25348397 N/A physical interaction ComPPI
ABL2 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
MTMR6 ERBB3 25348397 N/A physical interaction ComPPI
MTMR9 ERBB3 25348397 N/A physical interaction ComPPI
HCK ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
GFAP ERBB3 25348397 N/A physical interaction ComPPI
MRPS34 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ACTA2 ERBB3 25348397 N/A physical interaction ComPPI
ACTG2 ERBB3 25348397 N/A physical interaction ComPPI
DAPP1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
HNRNPH3 ERBB3 25348397 N/A physical interaction ComPPI
HBB ERBB3 25348397 N/A physical interaction ComPPI
HBE1 ERBB3 25348397 N/A physical interaction ComPPI
ACTA1 ERBB3 25348397 N/A physical interaction ComPPI
ATP5F1A ERBB3 25348397 N/A physical interaction ComPPI
SLC25A5 ERBB3 25348397 N/A physical interaction ComPPI
LGALS3BP ERBB3 25348397 N/A physical interaction ComPPI
MTMR8 ERBB3 25348397 N/A physical interaction ComPPI
PTCD3 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PCGF1 ERBB3 25348397 N/A physical interaction ComPPI
POU5F1 ERBB3 25348397 N/A physical interaction ComPPI
AIFM1 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPS22 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MRPS26 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ODF2L ERBB3 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RASA4 ERBB3 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FLYWCH1 ERBB3 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RPS27 ERBB3 25348397 N/A physical interaction ComPPI
HLA-DPA1 ERBB3 25348397 N/A physical interaction ComPPI
A1BG ERBB3 25348397 N/A physical interaction,surface plasmon resonance array ComPPI
PON2 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PLCG1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
NRG1 ERBB3 11555649 14525934 25348397 7592681 8702572 9565587 N/A experimental interaction detection,x-ray crystallography,physical interaction,comigration in non denaturing gel electrophoresis ComPPI,HPRD
ABL1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SLC31A1 ERBB3 25348397 N/A physical interaction ComPPI
MRPS18B ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ASB12 ERBB3 25348397 N/A physical interaction ComPPI
ERBB3 MUC1 11278868 12939402 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ERBB3 ZNF207 25348397 N/A physical interaction ComPPI
ERBB3 LRIG1 25348397 N/A physical interaction ComPPI
ERBB3 HSP90AA2P 25348397 N/A physical interaction ComPPI
ERBB3 TNS3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
ERBB3 TNS4 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
ERBB3 UQCR10 25348397 N/A physical interaction ComPPI
ERBB3 B3GLCT 25348397 N/A physical interaction ComPPI
ERBB3 PDF 25348397 N/A physical interaction ComPPI
ERBB3 TUBB8 25348397 N/A physical interaction ComPPI
ERBB3 YBEY 25348397 N/A physical interaction ComPPI
ERBB3 ANXA2P2 25348397 N/A physical interaction ComPPI
ERBB3 RPS27L 25348397 N/A physical interaction ComPPI
ERBB3 MRPS14 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERBB3 MRPS17 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERBB3 MRPS27 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERBB3 MRPS28 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERBB3 ACTBL2 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERBB3 ACTC1 25348397 N/A physical interaction ComPPI
ERBB3 HBG1 25348397 N/A physical interaction ComPPI
ERBB3 POTEE 25348397 N/A physical interaction ComPPI
ERBB3 POTEF 25348397 N/A physical interaction ComPPI
ERBB3 MRPS25 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ERBB3 NANOGP8 25348397 N/A physical interaction ComPPI
ERBB3 NANOG 25348397 N/A physical interaction ComPPI
ERBB3 PPM1K 25348397 N/A physical interaction ComPPI
ERBB3 PPM1M 25348397 N/A physical interaction ComPPI
ERBB3 PTPN20 25348397 N/A physical interaction ComPPI
ERBB3 DUSP18 25348397 N/A physical interaction ComPPI
ERBB3 DUSP29 25348397 N/A physical interaction ComPPI
ERBB3 PTPDC1 25348397 N/A physical interaction ComPPI
ERBB3 TPTE 25348397 N/A physical interaction ComPPI
ERBB3 MTMR1 25348397 N/A physical interaction ComPPI
ERBB3 EYA4 25348397 N/A physical interaction ComPPI
ERBB3 ROR1 22439932 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ERBB3 POTEKP 24189400 24234451 25348397 association tandem affinity purification ComPPI,IntAct
MRPS23 ERBB3 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DUSP21 ERBB3 25348397 N/A physical interaction ComPPI
ERBB3 SOS1 11173924 14525934 N/A experimental interaction detection HPRD
AGTR2 ERBB3 10710290 14525934 N/A two hybrid HPRD
PTGES3 ERBB3 10095121 14525934 N/A experimental interaction detection,two hybrid HPRD
ERBB3 ERBB3 12154198 14525934 21575594 23436906 24234451 physical association experimental interaction detection,nuclear magnetic resonance,proximity ligation assay HPRD,IntAct
CDK5 ERBB3 12824184 14525934 N/A experimental interaction detection HPRD
ERBB3 FLNA 14525934 16729043 N/A experimental interaction detection HPRD
EGFR ERBB3 10527633 10572067 12648464 17145710 21278786 23436906 23866081 24189400 27898060 7929151 stimulant N/A OmniPath
NRG1 ERBB3 11555649 17697999 27898060 7477375 7514177 7592681 8702572 9168115 9565587 stimulant N/A OmniPath
ERBB3 GRB2 11173924 14967450 16729043 24189400 24658140 27898060 9756944 stimulant N/A OmniPath
ERBB3 PIK3CA 16729043 19411071 27898060 stimulant N/A OmniPath
ERBB3 PIK3R1 10383151 10572067 1154679 11546794 16273093 20227043 21278786 24189400 27898060 9130710 9756944 stimulant N/A OmniPath
ERBB2 ERBB3 10572067 10799311 11173924 12648465 15504738 17426253 19060928 19411071 20227043 21278786 22806884 23436906 23680147 23688700 24557338 25241761 27898060 7538656 8816440 9130710 stimulant N/A OmniPath
AR ERBB3 15542423 27898060 stimulant N/A OmniPath
ERBB3 GRB7 16189514 16273093 24189400 27898060 9516479 stimulant N/A OmniPath
PAK1 ERBB3 11546794 27898060 9516479 9694850 N/A N/A OmniPath
NRG2 ERBB3 27898060 7514177 9168114 9168115 stimulant N/A OmniPath
ERBB3 PIK3CD 16729043 27898060 stimulant N/A OmniPath
ERBB3 PIK3CB 16729043 27898060 stimulant N/A OmniPath
BTC ERBB3 27898060 9312020 N/A N/A OmniPath
AREG ERBB3 27898060 8702723 N/A N/A OmniPath
LRIG1 ERBB3 16123311 27898060 inhibition,stimulant N/A OmniPath
ERBB3 PIK3CG 16729043 27898060 stimulant N/A OmniPath
L1CAM ERBB3 22815787 27898060 N/A N/A OmniPath
EREG ERBB3 16829981 22891299 27898060 stimulant N/A OmniPath

Visualization










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