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GENE：ERN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ERN2
FullNmae endoplasmic reticulum to nucleus signaling 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16942
EnsembleID ENSG00000134398
Uniprot Q76MJ5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ERN2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ERN2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ERN2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ERN2 GO:0000287,GO:0004519,GO:0004521,GO:0004674,GO:0004674,GO:0005524,GO:0005783,GO:0005829,GO:0006397,GO:0006468,GO:0016075,GO:0030263,GO:0034976,GO:0036498,GO:0044322,GO:0045892,GO:0051082,GO:0070059,GO:0106310,GO:1990604,GO:1990604

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 ERN2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ERN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ERN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ERN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ERN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ERN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ERN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
HSPA5 ERN2 18624755 27898060 inhibition N/A OmniPath

Visualization










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