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GENE：FAIM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FAIM
FullNmae Fas apoptotic inhibitory molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18703
EnsembleID ENSG00000158234
Uniprot Q9NVQ4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FAIM apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FAIM apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FAIM GO:0005515,GO:0005737,GO:0006915,GO:0007249,GO:0050769,GO:1902042

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FAIM FASLG 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
FAIM FAS 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
FAIM FAF1 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
FAIM FADD 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
FAIM DAXX 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN
FAIM RIPK1 12702723 16498403 17942717 23069999 26192618 9184224 interaction type N/A ACSN

Source Target Pmid Interactiontype Methods Database
YBX1 FAIM 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FAIM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FAIM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FAIM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FAIM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FAIM N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000032BD73 FAIM 22532850 rna interference,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS000032BD73 FAIM 22532850 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000F31F4 FAIM 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 FAIM 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SPRY2 FAIM 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LMNA FAIM 25348397 N/A physical interaction ComPPI
XIAP FAIM 25348397 N/A physical interaction ComPPI
KLHDC2 FAIM 25348397 N/A physical interaction ComPPI
H2BC9 FAIM 24234451 30021884 physical association cross-linking study IntAct
H2BS1 FAIM 24234451 30021884 physical association cross-linking study IntAct
H1-1 FAIM 24234451 30021884 physical association cross-linking study IntAct

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