Gene Information gene info

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GENE：FBH1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FBH1
FullNmae F-box DNA helicase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13620
EnsembleID ENSG00000134452
Uniprot Q8NFZ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FBH1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBH1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBH1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FBH1 GO:0000724,GO:0000724,GO:0000785,GO:0001934,GO:0003678,GO:0003678,GO:0003690,GO:0003697,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0006281,GO:0006308,GO:0006974,GO:0015616,GO:0016567,GO:0016567,GO:0016853,GO:0016887,GO:0019005,GO:0031297,GO:0031297,GO:0032508,GO:0043138,GO:0043138,GO:0072429,GO:1902231,GO:2000042

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SKP1 FBH1 11956208 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
CUL1 FBH1 11956208 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 FBH1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FBH1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D FBH1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000285DCB FBH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 FBH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000353492 FBH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF FBH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 FBH1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 FBH1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIM2 FBH1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PCNA FBH1 25348397 N/A physical interaction ComPPI
SKP1 FBH1 11956208 14525934 24234451 25348397 27705803 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
HSP90AB1 FBH1 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SRC FBH1 23954233 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
RBX1 FBH1 11956208 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
UBC FBH1 25348397 N/A physical interaction ComPPI
HSP90AA1 FBH1 25348397 N/A physical interaction ComPPI
RPA1 FBH1 25348397 N/A physical interaction ComPPI
RALA FBH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD51 FBH1 23393192 24108124 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RPA2 FBH1 25348397 N/A physical interaction ComPPI
RPA3 FBH1 25348397 N/A physical interaction ComPPI
CUL1 FBH1 11956208 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SYNCRIP FBH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ZDHHC17 FBH1 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ESR1 FBH1 25348397 N/A physical interaction ComPPI
FBH1 RPL13A 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FBH1 HSP90AA2P 25348397 N/A physical interaction ComPPI
FBH1 DTL 25348397 N/A physical interaction ComPPI
FBH1 PRR3 25348397 N/A physical interaction ComPPI
FBH1 ILKAP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBH1 MRRF 25348397 N/A physical interaction ComPPI

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