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GENE：FBXW7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FBXW7
FullNmae F-box and WD repeat domain containing 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16712
EnsembleID ENSG00000109670
Uniprot Q969H0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FBXW7 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBXW7 autophagy 31010381 Human cancers with FBXW7 inactivation and SHOC2 overexpression would squeeze RPTOR from MTORC1, leading to MTORC1 inactivation and autophagy induction. retulator signature
FBXW7 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
FBXW7 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FBXW7 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FBXW7 GO:0001570,GO:0001944,GO:0005515,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005737,GO:0005739,GO:0005783,GO:0005794,GO:0005829,GO:0006281,GO:0007062,GO:0007219,GO:0010629,GO:0010629,GO:0010868,GO:0010883,GO:0010992,GO:0016567,GO:0019005,GO:0030324,GO:0030332,GO:0030332,GO:0030674,GO:0031146,GO:0031398,GO:0031625,GO:0031648,GO:0032880,GO:0042752,GO:0042802,GO:0043130,GO:0043161,GO:0043161,GO:0045741,GO:0045746,GO:0048471,GO:0048511,GO:0050816,GO:0050821,GO:0051443,GO:0055088,GO:0070374,GO:0090049,GO:0097027,GO:1901800,GO:1902806,GO:1903146,GO:1903378,GO:1903955,GO:1990452,GO:1990756,GO:2000060,GO:2000060,GO:2000346,GO:2000639,GO:2001205

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FBXW7 hsa:55294 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FBXW7 NOTCH1 11425854 11585921 17646408 23331499 stimulation N/A SignaLink
FBXW7 NOTCH4 11585921 14672936 23331499 inhibition N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR FBXW7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FBXW7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FBXW7 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FBXW7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 FBXW7 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 FBXW7 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FBXW7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000008F0CF FBXW7 20042474 rna interference,inhibition array technology,western blot,northern blot,miRNA interference luciferase reporter assay miRSponge
URS00000B7E30 FBXW7 22270966 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001B341F FBXW7 21460851 rna interference,inhibition western blot,miRNA interference luciferase reporter assay miRSponge
URS00000F4AC3 FBXW7 16822819 25416803 mrna cleavage,inhibition array technology TarBase
URS000008F0CF FBXW7 20042474 25416803 mrna cleavage,inhibition array technology,western blot,northern blot,miRNA interference luciferase reporter assay TarBase
URS00000B7E30 FBXW7 22270966 24324762 25159729 25416803 25888377 27398136 28000896 mrna cleavage,inhibition array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001B341F FBXW7 20371350 21460851 25416803 26629048 mrna cleavage,inhibition nucleotide sequence identification,western blot,miRNA interference luciferase reporter assay TarBase
URS0000272039 FBXW7 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000F6E49 FBXW7 25269767 25416803 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS00001CC379 FBXW7 25269767 25416803 27648365 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000C85B2 FBXW7 25416803 25512615 25944166 26464659 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS00001CC4BD FBXW7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 FBXW7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031D186 FBXW7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB FBXW7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002CAE0C FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000202460 FBXW7 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 FBXW7 25416803 28149200 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00000B989F FBXW7 25416803 27167197 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000338542 FBXW7 25416803 27306418 27904771 mrna cleavage,inhibition quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00002E92A8 FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000032AE90 FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000AB32B FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F24A9 FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000035AC91 FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001DA458 FBXW7 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPK3 FBXW7 22135298 phosphorylation N/A PhosphoSite
PRKCI FBXW7 22135298 phosphorylation N/A PhosphoSite
SGK1 FBXW7 22135298 phosphorylation N/A PhosphoSite
PLK2 FBXW7 22135298 phosphorylation N/A PhosphoSite
MAPK1 FBXW7 22135298 phosphorylation N/A PhosphoSite
ATM FBXW7 22135298 phosphorylation N/A PhosphoSite
PRKCA FBXW7 22135298 phosphorylation N/A PhosphoSite
SKP1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 SKP1 25361965 interaction type N/A PTMCode2
RBX1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 RBX1 25361965 interaction type N/A PTMCode2
CDC6 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 CDC6 25361965 interaction type N/A PTMCode2
FBXW7 CUL1 25361965 interaction type N/A PTMCode2
CUL1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 HEY1 25361965 interaction type N/A PTMCode2
HEY1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 SREBF1 25361965 interaction type N/A PTMCode2
SREBF1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 JUN 25361965 interaction type N/A PTMCode2
JUN FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 MYC 25361965 interaction type N/A PTMCode2
MYC FBXW7 25361965 interaction type N/A PTMCode2
NOTCH1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 NOTCH1 25361965 interaction type N/A PTMCode2
CCNE1 FBXW7 25361965 interaction type N/A PTMCode2
FBXW7 CCNE1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 FBXW7 25348397 N/A physical interaction ComPPI
PIN1 FBXW7 25348397 N/A physical interaction ComPPI
HNRNPK FBXW7 25348397 N/A physical interaction ComPPI
BCAS2 FBXW7 25348397 N/A physical interaction ComPPI
MORF4L2 FBXW7 25348397 N/A physical interaction ComPPI
FBP2 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBP1 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
ANP32B FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
NPM1 FBXW7 18625840 25348397 27898060 N/A physical interaction ComPPI,OmniPath
MAGEA1 FBXW7 25348397 N/A physical interaction ComPPI
DPM1 FBXW7 25348397 N/A physical interaction ComPPI
TGFB1 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
TAF9 FBXW7 25348397 N/A physical interaction ComPPI
PPP1CB FBXW7 25348397 N/A physical interaction ComPPI
SKP1 FBXW7 11585921 14525934 15070733 21620836 23791182 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
MED21 FBXW7 25348397 N/A physical interaction ComPPI
MED8 FBXW7 25348397 N/A physical interaction ComPPI
HSP90AB1 FBXW7 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
EIF3E FBXW7 20890303 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RACK1 FBXW7 21860413 25348397 27898060 N/A physical interaction ComPPI,OmniPath
DDX17 FBXW7 25348397 N/A physical interaction ComPPI
MAGEF1 FBXW7 25348397 N/A physical interaction ComPPI
BEX1 FBXW7 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAGEC2 FBXW7 25348397 N/A physical interaction ComPPI
SMAD1 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
HRAS FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
EZH2 FBXW7 25348397 N/A physical interaction ComPPI
SUMF2 FBXW7 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NOTCH4 FBXW7 11585921 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FBXW7 JUN 14525934 16023596 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FBXW7 MYC 14525934 16023596 17157259 17314511 23791182 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
FBXW7 NOTCH1 11425854 11585921 14525934 17909182 20823234 23022380 24234451 25344755 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
FBXW7 PRKN 12628165 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FBXW7 CUL1 14525934 14603323 23108047 24234451 25348397 association,physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
FBXW7 SHPRH 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FBXW7 HEY1 11585921 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FBXW7 CCNE1 11533444 11565033 14525934 14536078 24234451 25348397 ubiquitination reaction,physical association coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
FBXW7 RFLNA 14525934 16169070 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
FBXW7 MMS22L 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FBXW7 LINGO1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FBXW7 ARL6IP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FBXW7 HIPK2 14525934 18765672 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
FBXW7 PPARGC1A 14525934 18198341 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
FBXW7 PSEN1 12354302 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
FBXW7 NFKB2 25348397 N/A physical interaction,physical interaction,tandem affinity purification ComPPI
FBXW7 WDR97 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FBXW7 MTOR 25348397 N/A physical interaction ComPPI
FBXW7 MYB 14525934 18765672 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
FBXW7 SREBF1 16054087 16825193 19126544 24298052 25348397 26759235 27898060 N/A physical interaction ComPPI,OmniPath
FBXW7 KLF5 25348397 N/A physical interaction ComPPI
FBXW7 CCNE2 19084516 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FBXW7 MYCN 19111882 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXW7 AURKA 25348397 N/A physical interaction ComPPI
FBXW7 DCLRE1C 25348397 N/A physical interaction ComPPI
FBXW7 HIF1A 25348397 N/A physical interaction ComPPI
FBXW7 NFE2L1 21953459 23623971 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FBXW7 TP63 25348397 N/A physical interaction ComPPI
FBXW7 RBX1 25348397 N/A physical interaction ComPPI
FBXW7 USP28 25348397 N/A physical interaction ComPPI
FBXW7 TOP2A 25348397 N/A physical interaction ComPPI
FBXW7 PSMA2 25348397 N/A physical interaction ComPPI
FBXW7 REST 25348397 N/A physical interaction ComPPI
FBXW7 GSK3B 25348397 N/A physical interaction ComPPI
FBXW7 RICTOR 25348397 N/A physical interaction ComPPI
FBXW7 GLMN 25348397 N/A physical interaction ComPPI
FBXW7 JAG1 25348397 N/A physical interaction ComPPI
FBXW7 AURKB 25348397 N/A physical interaction ComPPI
FBXW7 MED12 25348397 N/A physical interaction ComPPI
FBXW7 MED1 25348397 N/A physical interaction ComPPI
FBXW7 MED13 25348397 N/A physical interaction ComPPI
FBXW7 MED13L 25348397 N/A physical interaction ComPPI
FBXW7 MED14 25348397 N/A physical interaction ComPPI
FBXW7 MED23 25348397 N/A physical interaction ComPPI
FBXW7 MED16 25348397 N/A physical interaction ComPPI
FBXW7 MED15 25348397 N/A physical interaction ComPPI
FBXW7 MED4 25348397 N/A physical interaction ComPPI
FBXW7 MED24 25348397 N/A physical interaction ComPPI
FBXW7 MED20 25348397 N/A physical interaction ComPPI
FBXW7 MED22 25348397 N/A physical interaction ComPPI
FBXW7 MED27 25348397 N/A physical interaction ComPPI
FBXW7 MED10 25348397 N/A physical interaction ComPPI
FBXW7 MED9 25348397 N/A physical interaction ComPPI
FBXW7 MED17 25348397 N/A physical interaction ComPPI
FBXW7 MED11 25348397 N/A physical interaction ComPPI
FBXW7 MED19 25348397 N/A physical interaction ComPPI
FBXW7 MED29 25348397 N/A physical interaction ComPPI
FBXW7 MED30 25348397 N/A physical interaction ComPPI
FBXW7 MED31 25348397 N/A physical interaction ComPPI
FBXW7 MED6 25348397 N/A physical interaction ComPPI
FBXW7 CCNC 25348397 N/A physical interaction ComPPI
FBXW7 CCDC6 23108047 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FBXW7 STOML1 25348397 N/A physical interaction ComPPI
FBXW7 CDK2 25348397 N/A physical interaction ComPPI
FBXW7 HSP90AA1 25348397 N/A physical interaction ComPPI
FBXW7 HSP90AA2P 25348397 N/A physical interaction ComPPI
FBXW7 KLF2 23507969 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FBXW7 PTEN 25348397 N/A physical interaction ComPPI
FBXW7 NCOA3 25348397 N/A physical interaction ComPPI
FBXW7 CSF3R 25348397 N/A physical interaction ComPPI
FBXW7 UBE2QL1 25348397 N/A physical interaction ComPPI
FBXW7 MAP4K1 25348397 N/A physical interaction ComPPI
FBXW7 EYA1 25348397 N/A physical interaction ComPPI
FBXW7 YAP1 25348397 N/A physical interaction ComPPI
FBXW7 DAB2IP 25348397 N/A physical interaction ComPPI
FBXW7 MCL1 25348397 N/A physical interaction ComPPI
FBXW7 MOV10 25348397 N/A physical interaction ComPPI
FBXW7 NXF1 25348397 N/A physical interaction ComPPI
FBXW7 USP36 25348397 N/A physical interaction ComPPI
FBXW7 SNCA 25348397 N/A physical interaction ComPPI
FBXW7 CRY2 25348397 N/A physical interaction ComPPI
FBXW7 GATA3 24820417 25348397 27898060 N/A physical interaction ComPPI,OmniPath
FBXW7 CUL7 25348397 N/A physical interaction ComPPI
FBXW7 MAPK3 25348397 N/A physical interaction ComPPI
FBXW7 ANGPTL4 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW7 BCAS3 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW7 IL24 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW7 SCGB3A1 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW7 TRIM25 24234451 25348397 25640309 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
FBXW7 GATA2 25348397 N/A physical interaction ComPPI
FBXW7 NFE2L3 25348397 N/A physical interaction ComPPI
FBXW7 RUNX2 25348397 N/A physical interaction ComPPI
FBXW7 FAM83D 25348397 N/A physical interaction ComPPI
FBXW7 RND3 25348397 N/A physical interaction ComPPI
FBXW7 MYCBP2 25348397 N/A physical interaction ComPPI
FBXW7 FBXO45 25348397 N/A physical interaction ComPPI
FBXW7 HECTD1 25348397 N/A physical interaction ComPPI
FBXW7 CCT3 25348397 N/A physical interaction ComPPI
FBXW7 HSF1 25348397 N/A physical interaction ComPPI
FBXW7 FKBP5 25348397 N/A physical interaction ComPPI
FBXW7 DDX39A 25348397 N/A physical interaction ComPPI
FBXW7 YBX1 25348397 N/A physical interaction ComPPI
FBXW7 SERBP1 25348397 N/A physical interaction ComPPI
FBXW7 RAE1 25348397 N/A physical interaction ComPPI
FBXW7 FMR1 25348397 N/A physical interaction ComPPI
FBXW7 RPL29 25348397 N/A physical interaction ComPPI
FBXW7 TSEN34 25348397 N/A physical interaction ComPPI
FBXW7 RPL10L 25348397 N/A physical interaction ComPPI
FBXW7 CPSF3 25348397 N/A physical interaction ComPPI
FBXW7 NMT1 25348397 N/A physical interaction ComPPI
FBXW7 RBM28 25348397 N/A physical interaction ComPPI
FBXW7 SPRYD3 25348397 N/A physical interaction ComPPI
FBXW7 IPO4 25348397 N/A physical interaction ComPPI
FBXW7 CDK8 25348397 N/A physical interaction ComPPI
FBXW7 EP400 25348397 N/A physical interaction ComPPI
FBXW7 NAA10 25348397 N/A physical interaction ComPPI
FBXW7 ARID4B 25348397 N/A physical interaction ComPPI
FBXW7 SINHCAF 25348397 N/A physical interaction ComPPI
FBXW7 GTF3C2 25348397 N/A physical interaction ComPPI
FBXW7 MAX 25348397 N/A physical interaction ComPPI
FBXW7 AK6 25348397 N/A physical interaction ComPPI
FBXW7 RCOR1 25348397 N/A physical interaction ComPPI
FBXW7 H2AC7 25348397 N/A physical interaction ComPPI
FBXW7 H1-4 25348397 N/A physical interaction ComPPI
FBXW7 CREB3L2 25348397 N/A physical interaction ComPPI
FBXW7 CEBPZ 25348397 N/A physical interaction ComPPI
FBXW7 SIN3A 25348397 N/A physical interaction ComPPI
FBXW7 SSRP1 25348397 N/A physical interaction ComPPI
FBXW7 RIOK1 25348397 N/A physical interaction ComPPI
FBXW7 ACLY 25348397 N/A physical interaction ComPPI
FBXW7 CSNK1A1L 25348397 N/A physical interaction ComPPI
FBXW7 SMU1 25348397 N/A physical interaction ComPPI
FBXW7 GFPT2 25348397 N/A physical interaction ComPPI
FBXW7 ATG16L2 25348397 N/A physical interaction ComPPI
FBXW7 HADHA 25348397 N/A physical interaction ComPPI
FBXW7 TUBA1C 25348397 N/A physical interaction ComPPI
FBXW7 TMOD3 25348397 N/A physical interaction ComPPI
FBXW7 ACTR2 25348397 N/A physical interaction ComPPI
FBXW7 PRPH 25348397 N/A physical interaction ComPPI
FBXW7 MAP7D1 25348397 N/A physical interaction ComPPI
FBXW7 AP3D1 25348397 N/A physical interaction ComPPI
FBXW7 CLASP1 25348397 N/A physical interaction ComPPI
FBXW7 SNX8 25348397 N/A physical interaction ComPPI
FBXW7 PSMA4 25348397 N/A physical interaction ComPPI
FBXW7 MYO5A 25348397 N/A physical interaction ComPPI
FBXW7 ENO1 25348397 N/A physical interaction ComPPI
FBXW7 BRAF 25348397 N/A physical interaction ComPPI
FBXW7 SOX10 25348397 N/A physical interaction ComPPI
FBXW7 DEPTOR 25348397 N/A physical interaction ComPPI
FBXW7 FOXM1 25348397 N/A physical interaction ComPPI
FBXW7 FAAP20 25348397 N/A physical interaction ComPPI
FBXW7 STAT3 25348397 N/A physical interaction ComPPI
FBXW7 PLK1 25348397 N/A physical interaction ComPPI
FBXW7 CDX2 25348397 N/A physical interaction ComPPI
FBXW7 CTNNB1 25348397 N/A physical interaction ComPPI
FBXW7 SOX9 25348397 N/A physical interaction ComPPI
FBXW7 PA2G4 25348397 N/A physical interaction ComPPI
FBXW7 EGLN2 25348397 N/A physical interaction ComPPI
FBXW7 STYX 25348397 N/A physical interaction ComPPI
FBXW7 FBXW2 25348397 N/A physical interaction ComPPI
FBXW7 PRR36 25348397 N/A physical interaction ComPPI
FBXW7 CREB3L1 25348397 N/A physical interaction ComPPI
FBXW7 TRAF2 25348397 N/A physical interaction ComPPI
FBXW7 TP53 25348397 N/A physical interaction ComPPI
FBXW7 ARHGDIA 25348397 N/A physical interaction ComPPI
FBXW7 EXT1 25348397 N/A physical interaction ComPPI
FBXW7 TSC22D4 25348397 N/A physical interaction ComPPI
FBXW7 NONO 25348397 N/A physical interaction ComPPI
FBXW7 BLM 25348397 N/A physical interaction ComPPI
FBXW7 DISC1 25348397 N/A physical interaction ComPPI
FBXW7 NR3C1 25348397 N/A physical interaction ComPPI
FBXW7 CEBPD 25348397 N/A physical interaction ComPPI
FBXW7 MDM2 25348397 N/A pull down ComPPI
FBXW7 AKT1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 DVL1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 FANCC 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 HEMGN 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 GALNT12 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 IGFBP3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 MAP2K1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 MAPKAPK3 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 NANS 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 SEC61B 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 SHC1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 TMOD1 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 ZNF510 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
FBXW7 NUDCD2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
XPA FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
CDC34 FBXW7 25348397 N/A physical interaction ComPPI
MED28 FBXW7 25348397 N/A physical interaction ComPPI
PLK2 FBXW7 25348397 N/A physical interaction ComPPI
PPP3R2 FBXW7 24234451 24412244 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
BTG1 FBXW7 25348397 N/A physical interaction ComPPI
EBNA1BP2 FBXW7 25348397 N/A physical interaction ComPPI
FBXW7 FBXW7 21620836 23791182 24234451 association,physical association anti tag coimmunoprecipitation IntAct
PRKCA FBXW7 20815813 27898060 N/A N/A OmniPath
PLK2 FBXW7 22399798 27898060 inhibition N/A OmniPath
USP28 FBXW7 20399964 27898060 inhibition N/A OmniPath
FBXW7 CCNE1 11533444 11565033 11565034 12824889 14536078 15364936 15980150 16338364 16818231 17298674 17434132 17646408 18559665 21070969 22388891 24298052 27898060 inhibition,stimulant N/A OmniPath
FBXW7 MYC 15103331 15150404 15498494 15992821 16023596 17145710 17157259 17314511 17646408 17873522 20399964 20848231 20852628 20970423 22524983 25716680 25720964 27898060 inhibition,stimulant N/A OmniPath
FBXW7 NCOA3 18541364 27898060 inhibition N/A OmniPath
FBXW7 PPARGC1A 18198341 18541364 27898060 inhibition N/A OmniPath
FBXW7 TP63 20571051 27898060 inhibition N/A OmniPath
FBXW7 AURKA 15592418 19111882 22513362 27898060 inhibition N/A OmniPath
MAPK3 FBXW7 22608923 25753158 27898060 N/A N/A OmniPath
TP53 FBXW7 12824889 27898060 stimulant N/A OmniPath
FBXW7 SERBP1 18541364 27898060 inhibition N/A OmniPath
SGK1 FBXW7 21147854 21620836 27898060 stimulant N/A OmniPath
FBXW7 NOTCH1 11425854 11461910 11585921 15546612 17526737 17646408 17646409 17909182 20571051 20823234 21820430 22388891 23022380 24085301 25344755 26033182 26108681 27898060 inhibition,stimulant N/A OmniPath
FBXW7 JUN 16023596 18930588 27898060 inhibition N/A OmniPath
FBXW7 DAB2IP 27858941 27898060 inhibition N/A OmniPath
FBXW7 NOTCH4 11585921 1467294 27898060 inhibition N/A OmniPath
STYX FBXW7 27898060 28007894 inhibition N/A OmniPath
FBXW7 CCDC6 23108047 25885523 27898060 inhibition N/A OmniPath

Visualization










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