Gene Information gene info

  1. Home

GENE：TNIK

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TNIK
FullNmae TRAF2 and NCK interacting kinase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30765
EnsembleID ENSG00000154310
Uniprot Q9UKE5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TNIK necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TNIK GO:0000165,GO:0001934,GO:0004672,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0005856,GO:0006468,GO:0006468,GO:0007010,GO:0010243,GO:0016055,GO:0016324,GO:0030033,GO:0030036,GO:0035556,GO:0043408,GO:0046330,GO:0046330,GO:0046777,GO:0048812,GO:0048814,GO:0055037,GO:0070062,GO:0072659,GO:0098793,GO:0098978,GO:0099092,GO:0106310

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
TNIK TNIK 10521462 23180781 phosphorylation reaction in-gel kinase assay InnateDB
TNIK TRAF2 10521462 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCK1 TNIK 10521462 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AKAP9 TNIK 20005715 interaction type N/A PSP
NCK1 TNIK 20005715 interaction type N/A PSP
PPP2R1A TNIK 20005715 interaction type N/A PSP
TRAF2 TNIK 20005715 interaction type N/A PSP
NCK1 TNIK 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR TNIK 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TNIK 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 TNIK 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 TNIK 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TNIK 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 TNIK 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TNIK 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
TNIK TCF7L2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
NCK2 TNIK 25348397 N/A physical interaction ComPPI
PDE4DIP TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNRPB2 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SMARCE1 TNIK 25348397 N/A physical interaction ComPPI
PPP1R13B TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EIF3H TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GLRX3 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PCBP1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IMPDH2 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACTG1 TNIK 25348397 N/A physical interaction ComPPI
PPP2R1A TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SET TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TRAF6 TNIK 22904686 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
CALM1 TNIK 25348397 N/A anti bait coimmunoprecipitation ComPPI
CYCS TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KBTBD7 TNIK 25348397 N/A physical interaction ComPPI
MAPK1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SOS1 TNIK 25348397 N/A physical interaction ComPPI
NCK1 TNIK 10521462 14525934 17474147 24234451 25348397 physical association two hybrid,experimental interaction detection,peptide array,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
DSTN TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CLU TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NCOR2 TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRMT1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TCF7L2 TNIK 19816403 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
SNX6 TNIK 25348397 N/A physical interaction ComPPI
BUB3 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PSMA1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKB TNIK 22904686 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEFM TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CACYBP TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
FSCN1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
COPB2 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
WWC1 TNIK 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PSMD1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GOLGA4 TNIK 25348397 N/A physical interaction ComPPI
RAP2A TNIK 14525934 15342639 25348397 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
TNIK TRAF2 10521462 14525934 22904686 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
TNIK GSN 10521462 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TNIK NEDD4 25348397 N/A physical interaction ComPPI
TNIK DISC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK DST 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK SYNE1 25348397 N/A physical interaction ComPPI
TNIK TNKS 25348397 N/A physical interaction ComPPI
TNIK SPTBN1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK MACF1 25348397 N/A physical interaction ComPPI
TNIK SRGAP3 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK ANK2 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK TRIM2 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK DPYSL3 25348397 N/A physical interaction ComPPI
TNIK HARS1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK TIAM2 25348397 N/A physical interaction ComPPI
TNIK TUBB2A 25348397 N/A physical interaction ComPPI
TNIK AKAP9 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK DPYSL2 25348397 N/A physical interaction ComPPI
TNIK AGTPBP1 25348397 N/A physical interaction ComPPI
TNIK CNKSR2 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TNIK DYNC1H1 25348397 N/A physical interaction ComPPI
TNIK GSE1 25348397 N/A physical interaction ComPPI
TNIK PAFAH1B1 25348397 N/A physical interaction ComPPI
TNIK PPM1E 25348397 N/A physical interaction ComPPI
TNIK LTBR 25348397 N/A physical interaction ComPPI
TNIK CEP63 25348397 N/A physical interaction ComPPI
TNIK TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TNIK XPO1 25348397 N/A physical interaction ComPPI
TNIK SMURF1 25348397 N/A physical interaction ComPPI
TNIK EGFR 25348397 N/A physical interaction ComPPI
TNIK IL20RA 25348397 N/A physical interaction ComPPI
TNIK MRPS11 25348397 N/A physical interaction ComPPI
TNIK UBE2A 25348397 N/A physical interaction ComPPI
TNIK MAP3K7 22904686 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNIK TAB2 22904686 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNIK STK26 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
TNIK RANBP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK FKBP3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK ACAT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK STRAP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK GOT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK HNRNPA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK MYL12A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK SF3B6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK SORD 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK DHCR7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PSMD6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK GOT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK EMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PDCD5 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK RCC2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK ACP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PSMD13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PCBP3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK TFAM 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK NAA15 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK CNPY2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK ECHS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK ANXA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK CBR1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK MRPL14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK TRMT112 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK CMPK1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK UCHL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK SOD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK ACTR2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK MRPS16 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK OTUB1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PSAT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK TEAD3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PPIH 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK NUDC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK RUVBL2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK LRRC59 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK RPN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK NANS 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK ACAT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK MTHFD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK SARS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PSMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK BCAP31 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK PRPSAP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK SEPTIN4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK MYT1L 17043677 24234451 25348397 physical association two hybrid ComPPI,IntAct
TNIK CTNNB1 19816403 24234451 25348397 association anti bait coimmunoprecipitation,pull down ComPPI,IntAct
TNIK EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TNIK LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RRM1 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPS14 TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
LYAR TNIK 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TNIK TNIK 14525934 17192257 N/A experimental interaction detection HPRD
CALM2 TNIK 17353931 24234451 physical association anti bait coimmunoprecipitation IntAct
ERO1A TNIK 24234451 30021884 physical association cross-linking study IntAct
TNIK TRAF2 10521462 22904686 27898060 N/A N/A OmniPath
TNIK TCF7L2 19816403 20530691 27898060 stimulant N/A OmniPath

Visualization










  Return