GENE：FGFR1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FGFR1 |
| FullNmae | fibroblast growth factor receptor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3688 |
| EnsembleID | ENSG00000077782 |
| Uniprot | P11362 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FGFR1 | ferroptosis | 38349269 | Moreover, FGFR1 silencing reversed the protective effects of FGF12 overexpression on cell viability, oxidative stress, ferroptosis, and FGFR1/AMPK/NRF2 pathway. | retulator signature |
| FGFR1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| FGFR1 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| FGFR1 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FGFR1 | GO:0000165,GO:0001501,GO:0001764,GO:0001837,GO:0004713,GO:0005007,GO:0005007,GO:0005007,GO:0005515,GO:0005524,GO:0005576,GO:0005634,GO:0005829,GO:0005886,GO:0005886,GO:0006468,GO:0007169,GO:0007275,GO:0008201,GO:0008284,GO:0008284,GO:0008284,GO:0008543,GO:0008543,GO:0008543,GO:0008543,GO:0010518,GO:0010863,GO:0016020,GO:0016477,GO:0017134,GO:0017134,GO:0018108,GO:0031410,GO:0033674,GO:0042802,GO:0042803,GO:0043009,GO:0043235,GO:0043235,GO:0043406,GO:0043410,GO:0043410,GO:0043536,GO:0045595,GO:0045597,GO:0045666,GO:0046777,GO:0048015,GO:0048705,GO:0051897,GO:0051897,GO:0090722,GO:1905564,GO:2000546,GO:2001239 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| FGFR1 | hsa:2260 | path:hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04014 | Ras signaling pathway - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04015 | Rap1 signaling pathway - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04020 | Calcium signaling pathway - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04151 | PI3K-Akt signaling pathway - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04520 | Adherens junction - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04550 | Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04714 | Thermogenesis - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04810 | Regulation of actin cytoskeleton - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa04928 | Parathyroid hormone synthesis, secretion and action - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa05200 | Pathways in cancer - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa05205 | Proteoglycans in cancer - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa05215 | Prostate cancer - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa05218 | Melanoma - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa05224 | Breast cancer - Homo sapiens (human) |
| FGFR1 | hsa:2260 | path:hsa05230 | Central carbon metabolism in cancer - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FGF1 | FGFR1 | 11030354 14517404 16272825 16682805 21071413 23331499 26183471 26192618 8576175 9242465 | interaction type,stimulation | N/A | ACSN,SignaLink,SignaLink |
| FGF2 | FGFR1 | 11874475 18232728 18633355 18776941 19508171 19631971 21098712 22652804 23123598 25374926 26192618 9242465 | interaction type | N/A | ACSN |
| FGF4 | FGFR1 | 26192618 9242465 | interaction type | N/A | ACSN |
| FGF3 | FGFR1 | 26183471 26192618 | interaction type | N/A | ACSN |
| FGFR1 | FRS2 | 12767520 17496910 17673906 23331499 25467007 26192618 9660748 | interaction type,stimulation | N/A | ACSN,SignaLink,SignaLink |
| FGFR1 | SHC1 | 17496910 25467007 26192618 | interaction type | N/A | ACSN |
| FGFR1 | BNIP2 | 10551883 17496910 25467007 26192618 | interaction type | N/A | ACSN |
| GZMB | FGFR1 | 16798735 23180781 | protein cleavage | protease assay | InnateDB |
| FGFR1 | GRB14 | 10713090 23331499 | stimulation | N/A | SignaLink |
| FGFR1 | SHB | 23331499 7537362 | stimulation | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CRK | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| FRS2 | FGFR1 | 20005715 | interaction type | N/A | PSP |
| FRS3 | FGFR1 | 20005715 | interaction type | N/A | PSP |
| GRB14 | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| GRB2 | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| NCK2 | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| PIK3R1 | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| SH3BP2 | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| SHB | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| SHC1 | FGFR1 | 20005715 | interaction type | N/A | PSP,SignaLink |
| FRS2 | FGFR1 | 10629055 11090629 11090629 11877385 20005715 20005715 21071413 9660748 9660748 | N/A | N/A | SignaLink |
| FRS3 | FGFR1 | 20005715 20005715 21071413 9660748 | N/A | N/A | SignaLink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | FGFR1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| E2F1 | FGFR1 | 19303924 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| ETS1 | FGFR1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | FGFR1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | FGFR1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | FGFR1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | FGFR1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HOPX | FGFR1 | 21256618 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| KLF10 | FGFR1 | 23569208 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RB1 | FGFR1 | 19303924 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SP1 | FGFR1 | 23569208 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| DAND5 | FGFR1 | 23569208 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARA | FGFR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARB | FGFR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RARG | FGFR1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000032BD73 | FGFR1 | 23296701 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | miRSponge |
| URS00000F0F49 | FGFR1 | 20065103 | rna interference,inhibition | miRNA interference luciferase reporter assay | miRSponge |
| URS00000F0F49 | FGFR1 | 20065103 23263626 23803556 25416803 | mrna cleavage,inhibition | array technology,western blot,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS000032BD73 | FGFR1 | 23296701 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS00000EC1BE | FGFR1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001C3AC1 | FGFR1 | 23622248 25416803 27714806 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,immunohistochemistry,clash,miRNA interference luciferase reporter assay | TarBase |
| URS000016D2D4 | FGFR1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000160683 | FGFR1 | 23962428 24616020 25416803 26701625 | mrna cleavage,inhibition | array technology,experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
| URS00001C770D | FGFR1 | 24463821 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00000F6E49 | FGFR1 | 23263626 25416803 | mrna cleavage,inhibition | array technology,northern blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay | TarBase |
| URS000040828B | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CE28 | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EEF5F | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000753AD | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000038446A | FGFR1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058BB84 | FGFR1 | 25416803 26451614 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS00002971AB | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000060AABB | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002367FA | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00006097A6 | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB0E | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00005F1B8C | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | FGFR1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MAPK3 | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| BMX | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| MAPK14 | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| MAPK1 | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| PRKCE | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | ITGB4 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | ZMYM2 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | AMOTL2 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | PDP1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | PDK1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | LDHA | 22135298 | phosphorylation | N/A | PhosphoSite |
| FGFR1 | ACAT1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| RPS6KA3 | FGFR1 | 22135298 | phosphorylation | N/A | PhosphoSite |
| GRB14 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | GRB14 | 25361965 | interaction type | N/A | PTMCode2 |
| FGF2 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FGF2 | 25361965 | interaction type | N/A | PTMCode2 |
| FGF4 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FGF4 | 25361965 | interaction type | N/A | PTMCode2 |
| KL | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | KL | 25361965 | interaction type | N/A | PTMCode2 |
| FGF9 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FGF9 | 25361965 | interaction type | N/A | PTMCode2 |
| FGF10 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FGF10 | 25361965 | interaction type | N/A | PTMCode2 |
| MMP2 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | MMP2 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | SOS1 | 25361965 | interaction type | N/A | PTMCode2 |
| SOS1 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | SHC1 | 25361965 | interaction type | N/A | PTMCode2 |
| SHC1 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGF5 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FGF5 | 25361965 | interaction type | N/A | PTMCode2 |
| IL17RD | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | IL17RD | 25361965 | interaction type | N/A | PTMCode2 |
| FLRT3 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FLRT3 | 25361965 | interaction type | N/A | PTMCode2 |
| FGF23 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FGF23 | 25361965 | interaction type | N/A | PTMCode2 |
| CDH1 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | CDH1 | 25361965 | interaction type | N/A | PTMCode2 |
| FLG | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FLG | 25361965 | interaction type | N/A | PTMCode2 |
| GRB2 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | GRB2 | 25361965 | interaction type | N/A | PTMCode2 |
| CRK | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | CRK | 25361965 | interaction type | N/A | PTMCode2 |
| FRS2 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | FRS2 | 25361965 | interaction type | N/A | PTMCode2 |
| PIK3R1 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | PIK3R1 | 25361965 | interaction type | N/A | PTMCode2 |
| SHB | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | SHB | 25361965 | interaction type | N/A | PTMCode2 |
| CTNNB1 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | CTNNB1 | 25361965 | interaction type | N/A | PTMCode2 |
| KPNB1 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | KPNB1 | 25361965 | interaction type | N/A | PTMCode2 |
| PIK3R2 | FGFR1 | 25361965 | interaction type | N/A | PTMCode2 |
| FGFR1 | PIK3R2 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| NCK2 | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| PIK3R2 | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| FRS3 | FGFR1 | 25348397 | N/A | two hybrid,physical interaction,in vitro | ComPPI |
| YES1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| S100B | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| IGHG1 | FGFR1 | 15174051 24234451 25348397 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| HSP90AB1 | FGFR1 | 22939624 24234451 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
| CRK | FGFR1 | 10464310 24234451 25241761 25348397 | association,physical association | affinity chromatography technology,physical interaction,in vitro,proximity ligation assay | ComPPI,IntAct |
| SLC1A1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| VAV1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| SHB | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| SLA | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| TGFBR2 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| SH3BP2 | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| PIK3R1 | FGFR1 | 18412956 24234451 25241761 25348397 | association,physical association | coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,IntAct |
| SRC | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| FGF3 | FGFR1 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| SHC1 | FGFR1 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| SOS1 | FGFR1 | 24234451 25241761 25348397 | physical association | physical interaction,in vivo,proximity ligation assay | ComPPI,IntAct |
| NCK1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| GRB2 | FGFR1 | 25348397 | N/A | in vivo | ComPPI |
| CREBBP | FGFR1 | 24234451 25241761 25348397 | physical association | physical interaction,in vitro,in vivo,proximity ligation assay | ComPPI,IntAct |
| FGFR2 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| FGF5 | FGFR1 | 25348397 | N/A | physical interaction,physical interaction,biochemical,in vivo | ComPPI |
| ITK | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| FRS2 | FGFR1 | 21765395 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction,in vitro,in vivo | ComPPI,IntAct |
| KPNB1 | FGFR1 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| HSP90AA1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| IFNGR1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | FGFR1 | 11401320 24234451 25241761 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction,proximity ligation assay | ComPPI,IntAct |
| GRB14 | FGFR1 | 25348397 | N/A | two hybrid,physical interaction,in vitro,in vivo | ComPPI |
| TNS2 | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| NECTIN1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| L1CAM | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| OPCML | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| GAD1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| AGER | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| FGF9 | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| FGF10 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| RPS6KA3 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| RPS6KA1 | FGFR1 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| PDP1 | FGFR1 | 25348397 | N/A | physical interaction | ComPPI |
| PKM | FGFR1 | 25348397 | N/A | physical interaction,protein kinase assay | ComPPI |
| FGFR1 | NCAM1 | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| FGFR1 | MMP2 | 25348397 | N/A | in vitro,in vivo | ComPPI |
| FGFR1 | EPHA4 | 25348397 | N/A | two hybrid,physical interaction,in vivo | ComPPI |
| FGFR1 | FGF6 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| FGFR1 | FGF7 | 25348397 | N/A | in vitro | ComPPI |
| FGFR1 | FGF4 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| FGFR1 | FGF8 | 24234451 25241761 25348397 | physical association | physical interaction,in vitro,in vivo,proximity ligation assay,surface plasmon resonance array | ComPPI,IntAct |
| FGFR1 | FGF17 | 25348397 | N/A | physical interaction,in vitro | ComPPI |
| FGFR1 | FGF18 | 25348397 | N/A | in vitro | ComPPI |
| FGFR1 | RTN3 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| FGFR1 | FGF1 | 10830168 18441324 24234451 25241761 25348397 | physical association | cross-linking study,surface plasmon resonance,x-ray crystallography,physical interaction,in vitro,in vivo,proximity ligation assay,surface plasmon resonance array | ComPPI,IntAct |
| FGFR1 | FDPS | 25348397 | N/A | two hybrid,physical interaction,in vitro,in vivo | ComPPI |
| FGFR1 | FGF2 | 10490103 11030354 23597563 24234451 25348397 26267536 | N/A | coimmunoprecipitation,cross-linking study,nuclear magnetic resonance,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,biochemical,in vitro,in vivo | ComPPI,IntAct |
| FGFR1 | BNIP2 | 25348397 | N/A | physical interaction,in vitro,in vivo | ComPPI |
| FGFR1 | IL17RD | 25348397 | N/A | in vivo | ComPPI |
| FGFR1 | HSPG2 | 24234451 24509440 25348397 | physical association | enzyme linked immunosorbent assay | ComPPI,IntAct |
| FGFR1 | PLCG1 | 1656221 20932831 23063561 24234451 25241761 25348397 8321198 | phosphorylation reaction,association,physical association | anti bait coimmunoprecipitation,bioluminescence resonance energy transfer,isothermal titration calorimetry,pull down,phosphorylation reaction,physical interaction,protein kinase assay,proximity ligation assay | ComPPI,IntAct |
| FGFR1 | STAT3 | 20388777 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| FGFR1 | JAK2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | NEDD4 | 21765395 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,fluorescence polarization spectroscopy,peptide array,pull down,physical interaction | ComPPI,IntAct |
| FGFR1 | PPP2R1B | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | FGF23 | 19966287 24234451 25348397 | physical association | molecular sieving,surface plasmon resonance,physical interaction,surface plasmon resonance array | ComPPI,IntAct |
| FGFR1 | PTK6 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | HSP90AA2P | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | ERBB3 | 16273093 24234451 25348397 | N/A | protein array,physical interaction | ComPPI,IntAct |
| FGFR1 | CDK9 | 23602568 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| FGFR1 | CDC20 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TSPAN3 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | CEACAM21 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | IL20RB | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | LGALS8 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | GINM1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | DLK1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | LTBR | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TNFRSF10B | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | EVI2A | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | MREG | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | HEPACAM2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | GOLGA7B | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | LDLRAD4 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | CTNNB1 | 11401320 24234451 25241761 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction,proximity ligation assay | ComPPI,IntAct |
| FGFR1 | RTN1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TNK2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | AKT1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | FAM8A1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TMEM30B | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | LRRN2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | LITAF | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | RUSF1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | ZDHHC11 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | FCGRT | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | IL27RA | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | RAET1E | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | ARMH4 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | MANSC1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TPCN2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | CD79B | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | SCN3B | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TEX45 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | HTR1A | 22035699 22553035 24234451 25348397 27898060 | physical association | bioluminescence resonance energy transfer,physical interaction,confocal microscopy,proximity ligation assay | ComPPI,IntAct,OmniPath |
| FGFR1 | FLRT1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | ANOS1 | 19696444 24234451 25348397 | colocalization,physical association | cross-linking study,surface plasmon resonance,physical interaction,confocal microscopy,surface plasmon resonance array | ComPPI,IntAct |
| FGFR1 | RASA1 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | CDH2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | ZMYM2 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | KLB | 19059246 24234451 25348397 | N/A | surface plasmon resonance,physical interaction,surface plasmon resonance array | ComPPI,IntAct |
| FGFR1 | CDH11 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | TGFBR3 | 25348397 | N/A | physical interaction | ComPPI |
| FGFR1 | FGF19 | 19706524 24234451 25348397 | physical association | physical interaction,solid phase assay | ComPPI,IntAct |
| FGFR1 | ATG5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| FGFR1 | NOSTRIN | 22751148 24234451 25348397 | physical association | anti bait coimmunoprecipitation,two hybrid,pull down | ComPPI,IntAct |
| FGFR1 | MFHAS1 | 24234451 25348397 29513927 | N/A | protein array | ComPPI,IntAct |
| CTPS2 | FGFR1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| FGFR1 | FGFR1 | 19696444 20133753 24234451 | N/A | cross-linking study,x-ray crystallography | IntAct |
| HSPD1 | FGFR1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| FGFR1 | TRPC1 | 15758179 27898060 | N/A | N/A | OmniPath |
| PRKCE | FGFR1 | 23564461 27898060 | stimulant | N/A | OmniPath |
| FGFR1 | CTTN | 12601080 27898060 | inhibition | N/A | OmniPath |
| EGFR | FGFR1 | 12601080 27898060 9880324 | N/A | N/A | OmniPath |
| FGFR1 | ITGB4 | 11438664 23677256 27898060 | N/A | N/A | OmniPath |
| GZMB | FGFR1 | 16798735 27898060 | N/A | N/A | OmniPath |
| FGFR1 | GNA13 | 12399457 27898060 | N/A | N/A | OmniPath |
| FGFR1 | PDK1 | 22195962 27898060 | stimulant | N/A | OmniPath |
| FGFR1 | KPNA2 | 15342649 27898060 | N/A | N/A | OmniPath |
| MAPK3 | FGFR1 | 23405013 27898060 | inhibition | N/A | OmniPath |
| MAPK14 | FGFR1 | 18411303 20626350 27898060 | inhibition | N/A | OmniPath |
| FGFR1 | STAT2 | 27898060 7532278 | N/A | N/A | OmniPath |
| FGFR1 | IRF3 | 14703513 27898060 9463386 | N/A | N/A | OmniPath |
| E2F1 | FGFR1 | 19303924 27898060 | stimulant | N/A | OmniPath |
| FGFR1 | BCAR1 | 11019781 11604500 12480533 12601080 15316024 15817476 27898060 8621540 8670206 | stimulant | N/A | OmniPath |
| MMP2 | FGFR1 | 27898060 8692946 | N/A | N/A | OmniPath |
| FGFR1 | RPS6KA3 | 10980595 12601080 17785202 18156174 24141780 27898060 | N/A | N/A | OmniPath |
| RPS6KA3 | FGFR1 | 24141780 27898060 | N/A | N/A | OmniPath |
| MAPK1 | FGFR1 | 23405013 27898060 | inhibition | N/A | OmniPath |
| FGFR1 | HES1 | 27898060 9389649 | N/A | N/A | OmniPath |
| FGFR1 | FRS2 | 10629055 11090629 11877385 21765395 27898060 9632781 9660748 | stimulant | N/A | OmniPath |
| FGFR1 | LDHA | 21969607 27898060 | stimulant | N/A | OmniPath |
| FGF1 | FGFR1 | 10336501 10830168 11030354 11032250 1722683 18441324 18940940 22244757 25241761 27898060 7730326 8576175 8663044 | stimulant | N/A | OmniPath |
| FGFR1 | SHB | 27898060 7537362 | stimulant | N/A | OmniPath |
| SHB | FGFR1 | 12181353 27898060 7516330 7537362 8622701 | N/A | N/A | OmniPath |
| FGFR1 | ANP32A | 15287743 27898060 | N/A | N/A | OmniPath |
| FGF5 | FGFR1 | 27898060 8386828 | stimulant | N/A | OmniPath |
| FGFR1 | SYNCRIP | 12601080 27898060 | inhibition | N/A | OmniPath |
| FGFR1 | PDP1 | 24486017 24962578 27898060 | N/A | N/A | OmniPath |
| ANOS1 | FGFR1 | 19696444 27898060 | N/A | N/A | OmniPath |
| FGF19 | FGFR1 | 16597617 27898060 | stimulant | N/A | OmniPath |
| FGFR1 | AMOTL2 | 21937427 27898060 | N/A | N/A | OmniPath |
| FGFR1 | SLBP | 12588979 27898060 | N/A | N/A | OmniPath |