Gene Information gene info

  1. Home

GENE：FGG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FGG
FullNmae fibrinogen gamma chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3694
EnsembleID ENSG00000171557
Uniprot P02679

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FGG apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FGG apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FGG GO:0005102,GO:0005102,GO:0005198,GO:0005201,GO:0005201,GO:0005515,GO:0005576,GO:0005577,GO:0005615,GO:0005615,GO:0005615,GO:0005788,GO:0005886,GO:0007160,GO:0007160,GO:0009306,GO:0009897,GO:0009986,GO:0031091,GO:0031093,GO:0031639,GO:0034116,GO:0036345,GO:0042730,GO:0042802,GO:0045907,GO:0045921,GO:0046872,GO:0050714,GO:0050839,GO:0051258,GO:0051592,GO:0062023,GO:0062023,GO:0065003,GO:0070062,GO:0070374,GO:0070527,GO:0070527,GO:0071347,GO:0071354,GO:0072378,GO:0072378,GO:0072562,GO:0090277,GO:1900026,GO:1902042,GO:2000352

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FGG hsa:2266 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
FGG hsa:2266 path:hsa04611 Platelet activation - Homo sapiens (human)
FGG hsa:2266 path:hsa04613 Neutrophil extracellular trap formation - Homo sapiens (human)
FGG hsa:2266 path:hsa05150 Staphylococcus aureus infection - Homo sapiens (human)
FGG hsa:2266 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTR9 FGG 17911113 23180781 physical association anti tag coimmunoprecipitation InnateDB
FGG CDC73 17911113 23180781 physical association anti tag coimmunoprecipitation InnateDB
LEO1 FGG 17911113 23180781 physical association anti tag coimmunoprecipitation InnateDB
FGG STAT3 17911113 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL7R FGG 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
FGG HRG 21757718 23180781 physical association surface plasmon resonance InnateDB
F2 FGG 21757718 23180781 physical association surface plasmon resonance InnateDB
PITX3 FGG 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CEBPA FGG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FGG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FGG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FGG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 FGG 11460505 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 FGG N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002E92A8 FGG 20570858 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000076995 FGG 20570858 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000272A3D FGG 20570858 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000081E1F FGG 20570858 rna interference,inhibition experimental interaction detection,miRNA interference luciferase reporter assay miRSponge
URS0000081E1F FGG 20570858 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS0000076995 FGG 20570858 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS00002E92A8 FGG 20570858 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,miRNA interference luciferase reporter assay TarBase
URS0000272A3D FGG 20570858 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000753AD FGG 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A FGG 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F FGG 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 FGG 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000010BD8D FGG 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 FGG 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CA8 FGG 25348397 N/A physical interaction ComPPI
RING1 FGG 25348397 N/A physical interaction ComPPI
H2BC4 FGG 25348397 N/A physical interaction ComPPI
KHDRBS2 FGG 25348397 N/A physical interaction ComPPI
ITGAV FGG 24234451 24789099 25348397 physical association fluorescence-activated cell sorting ComPPI,IntAct
VTN FGG 11744726 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SERPINA5 FGG 14525934 25348397 8384496 N/A experimental interaction detection,in vitro ComPPI,HPRD
ITGB3 FGG 10747940 14525934 24234451 24789099 25348397 25398877 27898060 physical association experimental interaction detection,fluorescence-activated cell sorting,physical interaction,enzyme linked immunosorbent assay,in vitro ComPPI,HPRD,IntAct,OmniPath
ITGA2B FGG 25348397 N/A physical interaction ComPPI
MAPK6 FGG 25348397 N/A physical interaction ComPPI
FGB FGG 12356313 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ITGAM FGG 11073102 14525934 25348397 27898060 9712878 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CX3CL1 FGG 24234451 24789099 25348397 physical association fluorescence-activated cell sorting,enzyme linked immunosorbent assay ComPPI,IntAct
DDX19B FGG 25348397 N/A physical interaction ComPPI
ASCC1 FGG 25348397 N/A physical interaction ComPPI
NUP93 FGG 25348397 N/A physical interaction ComPPI
ALDH2 FGG 25348397 N/A physical interaction ComPPI
ICAM1 FGG 14525934 24234451 25241761 25348397 27898060 7822297 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct,OmniPath
ITGA5 FGG 24234451 24789099 25348397 physical association enzyme linked immunosorbent assay ComPPI,IntAct
MTMR8 FGG 25348397 N/A physical interaction ComPPI
FGG F13B 14525934 25348397 27898060 8756701 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
FGG VKORC1 25348397 N/A physical interaction ComPPI
FGG FN1 25348397 N/A physical interaction ComPPI
FGG ASB6 25348397 N/A physical interaction ComPPI
FGG ASB7 25348397 N/A physical interaction ComPPI
FGG ASB12 25348397 N/A physical interaction ComPPI
FGG CHD9 25348397 N/A physical interaction ComPPI
FGG H2BC11 25348397 N/A physical interaction ComPPI
FGG SNX27 25348397 N/A physical interaction ComPPI
FGG CDK15 25348397 N/A physical interaction ComPPI
FGG CCNYL1 25348397 N/A physical interaction ComPPI
F13A1 FGG 10828988 14525934 25348397 27898060 8905624 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
FGA FGG 12356313 14525934 14992584 18294856 21475196 24234451 25348397 physical association experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,in vitro,atomic force microscopy ComPPI,HPRD,IntAct
FGG FGG 12501189 14525934 9333233 N/A experimental interaction detection HPRD
HSPD1 FGG 24234451 30021884 physical association cross-linking study IntAct
FGG ITGB1 15031111 27898060 N/A N/A OmniPath
FGG FN1 2243140 27898060 inhibition N/A OmniPath
IL7R FGG 20167604 27898060 N/A N/A OmniPath
FGG ITGB2 16601240 27898060 N/A N/A OmniPath
FGG ITGA2B 2018974 27898060 N/A N/A OmniPath
FGG ITGA5 15031111 27898060 N/A N/A OmniPath
FGG VTN 11744726 2243140 27898060 inhibition N/A OmniPath
FGG VWF 2243140 27898060 inhibition N/A OmniPath
FGG ITGAV 15031111 27898060 N/A N/A OmniPath

Visualization










  Return