Gene Information gene info

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GENE：FIGNL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FIGNL1
FullNmae fidgetin like 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13286
EnsembleID ENSG00000132436
Uniprot Q6PIW4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FIGNL1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FIGNL1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FIGNL1 GO:0000226,GO:0000228,GO:0000287,GO:0001649,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0007140,GO:0008568,GO:0010569,GO:0016787,GO:0016887,GO:0033687,GO:0043066,GO:0046034,GO:0048471,GO:0051726,GO:0070062,GO:0071479,GO:2001243

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 FIGNL1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 FIGNL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 FIGNL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 FIGNL1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 FIGNL1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 FIGNL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FIGNL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FIGNL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000DDD35 FIGNL1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS0000486E0B FIGNL1 20371350 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C3F6 FIGNL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 FIGNL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000412AC7 FIGNL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000759EB8 FIGNL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C FIGNL1 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000059EB31 FIGNL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CCD18 FIGNL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003AD2AA FIGNL1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GCC1 FIGNL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
JUN FIGNL1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
TSC22D3 FIGNL1 25348397 N/A physical interaction ComPPI
NTRK1 FIGNL1 25348397 N/A physical interaction ComPPI
F9 FIGNL1 25348397 N/A physical interaction ComPPI
ITGB1BP1 FIGNL1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAD51 FIGNL1 25348397 N/A physical interaction ComPPI
CALD1 FIGNL1 25348397 N/A physical interaction ComPPI
RFXANK FIGNL1 25348397 N/A physical interaction ComPPI
VCPIP1 FIGNL1 25348397 N/A physical interaction ComPPI
KDM1A FIGNL1 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TKT FIGNL1 25348397 N/A physical interaction ComPPI
JPT2 FIGNL1 25348397 N/A physical interaction ComPPI
THAP11 FIGNL1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AZU1 FIGNL1 25348397 N/A physical interaction ComPPI
AVIL FIGNL1 25348397 N/A physical interaction ComPPI
HSPA1L FIGNL1 25348397 N/A physical interaction ComPPI
RABL2A FIGNL1 25348397 N/A physical interaction ComPPI
FIGNL1 H1-4 24234451 30021884 physical association cross-linking study IntAct

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