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GENE：FZD9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FZD9
FullNmae frizzled class receptor 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4047
EnsembleID ENSG00000188763
Uniprot O00144

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FZD9 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FZD9 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FZD9 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FZD9 GO:0001503,GO:0001836,GO:0004930,GO:0005737,GO:0005789,GO:0005794,GO:0005886,GO:0005886,GO:0007186,GO:0007399,GO:0007405,GO:0007611,GO:0009986,GO:0016020,GO:0017147,GO:0017147,GO:0030183,GO:0030501,GO:0031527,GO:0031966,GO:0035567,GO:0042803,GO:0042813,GO:0042813,GO:0043065,GO:0043524,GO:0043524,GO:0046982,GO:0048471,GO:0051480,GO:0051726,GO:0051902,GO:0060070,GO:0060546,GO:0090263,GO:0098794,GO:0098978,GO:0099173,GO:0099566,GO:1901029,GO:1904393,GO:1904394,GO:1990523,GO:2000179

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FZD9 hsa:8326 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)
FZD9 hsa:8326 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
FZD9 hsa:8326 path:hsa04390 Hippo signaling pathway - Homo sapiens (human)
FZD9 hsa:8326 path:hsa04550 Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)
FZD9 hsa:8326 path:hsa04916 Melanogenesis - Homo sapiens (human)
FZD9 hsa:8326 path:hsa04934 Cushing syndrome - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05010 Alzheimer disease - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05200 Pathways in cancer - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05217 Basal cell carcinoma - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05224 Breast cancer - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
FZD9 hsa:8326 path:hsa05226 Gastric cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
WNT2 FZD9 12138115 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
YBX1 FZD9 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF FZD9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FZD9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 FZD9 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000025EABA FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 FZD9 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000020CEC2 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003D8730 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000498DAA FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008931A FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003AFAD1 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 FZD9 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A FZD9 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 FZD9 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D FZD9 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C FZD9 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000059EB31 FZD9 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 FZD9 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F FZD9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 FZD9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 FZD9 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F7766 FZD9 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
WNT2 FZD9 25361965 interaction type N/A PTMCode2
FZD9 WNT2 25361965 interaction type N/A PTMCode2
WNT7A FZD9 25361965 interaction type N/A PTMCode2
FZD9 WNT7A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FZD9 WNT7A 14525934 15705594 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FZD9 MDFI 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
FZD9 WNT2 12138115 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FZD9 WNT1 14525934 25348397 9147651 N/A experimental interaction detection,in vivo ComPPI,HPRD
FZD9 SIAH1 25348397 N/A physical interaction ComPPI
FZD9 KRTAP10-3 25348397 N/A physical interaction ComPPI
WNT2 FZD9 12138115 24032637 27898060 stimulant N/A OmniPath
WNT1 FZD9 27898060 9147651 stimulant N/A OmniPath

Visualization










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