Gene Information gene info

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GENE：GGCT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GGCT
FullNmae gamma-glutamylcyclotransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21705
EnsembleID ENSG00000006625
Uniprot O75223

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GGCT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GGCT apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GGCT apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
GGCT GO:0001836,GO:0003839,GO:0003839,GO:0005829,GO:0005829,GO:0042803,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GGCT hsa:79017 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
GGCT hsa:79017 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 GGCT 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 GGCT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GGCT 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 GGCT 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000065D58 GGCT 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000007FBA GGCT 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F0C23 GGCT 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CFTR GGCT 25348397 N/A physical interaction ComPPI
EGFR GGCT 24189400 24234451 25348397 association tandem affinity purification ComPPI,IntAct
STK4 GGCT 23386615 24234451 25348397 association tandem affinity purification ComPPI,IntAct
NFKB1 GGCT 24234451 25348397 25609649 association tandem affinity purification ComPPI,IntAct
WDR1 GGCT 25348397 N/A physical interaction ComPPI
HECW2 GGCT 25348397 N/A physical interaction ComPPI
RASSF7 GGCT 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
APP GGCT 25348397 N/A physical interaction ComPPI

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