GENE：GPER1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GPER1 |
| FullNmae | G protein-coupled estrogen receptor 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4485 |
| EnsembleID | ENSG00000164850 |
| Uniprot | Q99527 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GPER1 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| GPER1 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GPER1 | GO:0000139,GO:0001934,GO:0001934,GO:0001956,GO:0002695,GO:0003682,GO:0004930,GO:0005496,GO:0005515,GO:0005634,GO:0005635,GO:0005654,GO:0005730,GO:0005737,GO:0005769,GO:0005783,GO:0005789,GO:0005794,GO:0005794,GO:0005802,GO:0005829,GO:0005886,GO:0005886,GO:0006954,GO:0007049,GO:0007186,GO:0007189,GO:0007204,GO:0007399,GO:0008284,GO:0008285,GO:0010628,GO:0010628,GO:0010629,GO:0010629,GO:0010948,GO:0014069,GO:0019228,GO:0030154,GO:0030263,GO:0030264,GO:0030284,GO:0030284,GO:0030335,GO:0030424,GO:0030425,GO:0030518,GO:0030518,GO:0030659,GO:0031966,GO:0032024,GO:0032591,GO:0032962,GO:0038054,GO:0042311,GO:0042734,GO:0043065,GO:0043198,GO:0043231,GO:0043280,GO:0043401,GO:0043410,GO:0043679,GO:0044327,GO:0045087,GO:0045095,GO:0045599,GO:0045742,GO:0045745,GO:0045944,GO:0045944,GO:0048471,GO:0048786,GO:0050728,GO:0050769,GO:0051055,GO:0051281,GO:0051480,GO:0051726,GO:0051897,GO:0051898,GO:0055037,GO:0070373,GO:0070374,GO:0070374,GO:0070474,GO:0071333,GO:0071356,GO:0071375,GO:0071389,GO:0071392,GO:0071392,GO:0090200,GO:0098686,GO:1903078,GO:1904706,GO:1990239,GO:2000353,GO:2000724,GO:2001238 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| GPER1 | hsa:2852 | path:hsa01522 | Endocrine resistance - Homo sapiens (human) |
| GPER1 | hsa:2852 | path:hsa04915 | Estrogen signaling pathway - Homo sapiens (human) |
| GPER1 | hsa:2852 | path:hsa04929 | GnRH secretion - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | GPER1 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | GPER1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | GPER1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GPER1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | GPER1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | GPER1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | GPER1 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000016C318 | GPER1 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E6479 | GPER1 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS00003758F0 | GPER1 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000210075 | GPER1 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | GPER1 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |
| URS000017EA6A | GPER1 | 25416803 28735896 | mrna cleavage,inhibition | clip | TarBase |