GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
GSKIP
FullNmae
GSK3B interacting protein
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:20343
EnsembleID
ENSG00000100744
Uniprot
Q9P0R6
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
GSKIP
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
GSKIP
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
GSKIP
GO:0004860,GO:0004860,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0006469,GO:0008631,GO:0019207,GO:0019901,GO:0030111,GO:0030111,GO:0034237,GO:0051018,GO:0051018,GO:0090263
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
YBX1
GSKIP
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
E2F4
GSKIP
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00002B7450
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000013E79D
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000005A8ED
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000043D2C1
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000008AA34
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000118224
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002C02E4
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS000015188E
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002CE0C6
GSKIP
20371350
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000236310
GSKIP
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS000006FDD4
GSKIP
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS000018C928
GSKIP
22473208
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000277201
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000367985
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000237AF9
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000285DCB
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS00001EFEC1
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000475586
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000032BDF4
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS00001B0D1E
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS0000272039
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
URS000042B108
GSKIP
25416803
27418678
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
BAG3
GSKIP
25348397
N/A
physical interaction
ComPPI
GSK3B
GSKIP
17353931
23455922
23602568
24234451
25348397
29568061
association,physical association
anti bait coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification
ComPPI,IntAct
PEX19
GSKIP
21988832
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
GSK3A
GSKIP
20368287
23602568
24234451
25348397
association,physical association
physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,tandem affinity purification
ComPPI,IntAct
TRIM25
GSKIP
25348397
N/A
physical interaction
ComPPI
EXT2
GSKIP
21988832
24234451
25348397
physical association
two hybrid,physical interaction,two hybrid array
ComPPI,IntAct
Visualization