Gene Information gene info

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GENE：GSTP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GSTP1
FullNmae glutathione S-transferase pi 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4638
EnsembleID ENSG00000084207
Uniprot P09211

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GSTP1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GSTP1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GSTP1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
GSTP1 GO:0000302,GO:0002674,GO:0004364,GO:0004364,GO:0004602,GO:0005504,GO:0005515,GO:0005576,GO:0005615,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0005829,GO:0006469,GO:0006693,GO:0006749,GO:0006749,GO:0006805,GO:0007417,GO:0008432,GO:0009890,GO:0010804,GO:0019207,GO:0031982,GO:0032691,GO:0032720,GO:0032872,GO:0032873,GO:0032930,GO:0034774,GO:0035726,GO:0035730,GO:0035731,GO:0035732,GO:0043066,GO:0043124,GO:0043407,GO:0043409,GO:0043508,GO:0043651,GO:0048147,GO:0051122,GO:0051771,GO:0070026,GO:0070062,GO:0070372,GO:0070373,GO:0070664,GO:0071222,GO:0071638,GO:0097057,GO:0098869,GO:1901687,GO:1904813,GO:2001237

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GSTP1 hsa:2950 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa00980 Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa00982 Drug metabolism - cytochrome P450 - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa01524 Platinum drug resistance - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa05200 Pathways in cancer - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa05204 Chemical carcinogenesis - DNA adducts - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa05215 Prostate cancer - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa05225 Hepatocellular carcinoma - Homo sapiens (human)
GSTP1 hsa:2950 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL7R GSTP1 20167604 23180781 physical association anti tag coimmunoprecipitation InnateDB
ISG15 GSTP1 16009940 23180781 physical association unspecified method InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 GSTP1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC GSTP1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C GSTP1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 GSTP1 18505928 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay,DNase I footprinting TFlink
SMARCA4 GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GSTP1 18971253 8206948 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 GSTP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CDX2 GSTP1 22580340 trascriptional regulation,stimulation inferred by curator TFlink
JUN GSTP1 8206948 trascriptional regulation,stimulation inferred by curator TFlink
MBD2 GSTP1 11406558 11960994 12543808 19856314 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 GSTP1 15013838 trascriptional regulation,stimulation inferred by curator TFlink
RELA GSTP1 15013838 trascriptional regulation,stimulation inferred by curator TFlink
SP1 GSTP1 8557630 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 GSTP1 8557630 trascriptional regulation,stimulation inferred by curator TFlink
AR GSTP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 GSTP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARA GSTP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARB GSTP1 N/A trascriptional regulation,stimulation inferred by curator TFlink
RARG GSTP1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 GSTP1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000032BD73 GSTP1 25416803 26396496 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
PRKCH GSTP1 22135298 phosphorylation N/A PhosphoSite
PRKCA GSTP1 22135298 phosphorylation N/A PhosphoSite
EGFR GSTP1 22135298 phosphorylation N/A PhosphoSite
FANCC GSTP1 25361965 interaction type N/A PTMCode2
GSTP1 FANCC 25361965 interaction type N/A PTMCode2
MAPK10 GSTP1 25361965 interaction type N/A PTMCode2
GSTP1 MAPK10 25361965 interaction type N/A PTMCode2
GSTP1 GSTP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HOXA1 GSTP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TXNL4A GSTP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SH3GLB1 GSTP1 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
KRT83 GSTP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ISG15 GSTP1 25348397 N/A physical interaction ComPPI
KRTAP10-7 GSTP1 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
E2F6 GSTP1 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
GSTP1 KRT31 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GSTP1 APPBP2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GSTP1 PTN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GSTP1 TRAF2 14525934 16636664 24234451 25241761 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
GSTP1 SUMO4 14525934 16236267 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
GSTP1 PNO1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GSTP1 FANCC 11433346 14499622 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
GSTP1 TGM2 14525934 25348397 9973324 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
GSTP1 MAPK8 11279197 12646564 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
GSTP1 SIRT7 25348397 N/A physical interaction ComPPI
GSTP1 CUL3 25348397 N/A physical interaction ComPPI
GSTP1 CUL2 25348397 N/A physical interaction ComPPI
GSTP1 CDK2 25348397 N/A physical interaction ComPPI
GSTP1 COPS5 25348397 N/A physical interaction ComPPI
GSTP1 MAPK1 25348397 N/A physical interaction ComPPI
GSTP1 MAP3K1 25348397 N/A physical interaction ComPPI
GSTP1 ACTA2 25348397 N/A physical interaction ComPPI
GSTP1 LIG4 25348397 N/A physical interaction ComPPI
GSTP1 FN1 25348397 N/A physical interaction ComPPI
GSTP1 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
GSTP1 MLH1 20706999 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GSTP1 ITGA4 25348397 N/A physical interaction ComPPI
GSTP1 SCAF1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GSTP1 FUS 25348397 N/A physical interaction ComPPI
GSTP1 KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GSTP1 KRTAP10-3 25348397 N/A physical interaction ComPPI
GSTP1 NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GSTP1 CUL7 25348397 N/A physical interaction ComPPI
GSTP1 HNRNPA1 25348397 N/A physical interaction ComPPI
GSTP1 NTRK1 25348397 N/A physical interaction ComPPI
GSTP1 GSTT2 25348397 N/A physical interaction ComPPI
GSTP1 GSTT2B 25348397 N/A physical interaction ComPPI
GSTP1 ACY1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTP1 ZNF518A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTP1 RBMX 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTP1 UBE2O 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTP1 FOXD4 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
GSTP1 FBXL12 25348397 N/A physical interaction ComPPI
GSTP1 MCM2 25348397 N/A physical interaction ComPPI
GSTP1 PRDX6 23164639 24234451 25348397 27898060 physical association physical interaction,proximity ligation assay ComPPI,IntAct,OmniPath
GSTP1 EGFR 25348397 N/A physical interaction ComPPI
GSTP1 DLD 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GSTP1 DLST 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GSTP1 SOD1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
GSTP1 UBE2A 25348397 N/A physical interaction ComPPI
GSTP1 DCAF4L2 25348397 N/A physical interaction ComPPI
GSTP1 KEAP1 25348397 N/A physical interaction ComPPI
GSTP1 GRB2 12577067 24234451 25348397 association pull down ComPPI,IntAct
GSTP1 MAP3K5 16636664 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GSTP1 MAPK14 16636664 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GSTP1 MDM2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
GSTP1 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GSTP1 MAP1LC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GSTP1 GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GSTP1 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GSTP1 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GSTP1 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
GSTP1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
GSTP1 JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
GSTP1 KRT33B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 KRT34 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 KRTAP3-3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 CARD10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 KRTAP3-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 LRP2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 KRTAP1-1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 TGM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 KRTAP6-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GSTP1 FHL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GABPB1 GSTP1 25348397 N/A physical interaction ComPPI
ATF2 GSTP1 22304920 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GSTP1 GSTP1 14525934 9398518 N/A experimental interaction detection HPRD
PRKCA GSTP1 15604283 27898060 N/A N/A OmniPath
EGFR GSTP1 19254954 26429914 27898060 stimulant N/A OmniPath
IL7R GSTP1 20167604 27898060 N/A N/A OmniPath
ISG15 GSTP1 16009940 27898060 N/A N/A OmniPath

Visualization










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