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GENE：HERPUD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HERPUD1
FullNmae homocysteine inducible ER protein with ubiquitin like domain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13744
EnsembleID ENSG00000051108
Uniprot Q15011

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HERPUD1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HERPUD1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HERPUD1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
HERPUD1 GO:0003674,GO:0005515,GO:0005783,GO:0005789,GO:0005789,GO:0005789,GO:0006511,GO:0006986,GO:0016020,GO:0030433,GO:0030968,GO:0030970,GO:0031396,GO:0032469,GO:0032469,GO:0034976,GO:0044322,GO:0044325,GO:0044325,GO:0045047,GO:1902236,GO:1902236,GO:1903069,GO:1903071,GO:1903071,GO:1990037,GO:1990756,GO:2001243

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HERPUD1 hsa:9709 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
APP HERPUD1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
AR HERPUD1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HERPUD1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXA1 HERPUD1 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC HERPUD1 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 HERPUD1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 HERPUD1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HERPUD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000508C13 HERPUD1 N/A 15685193 rna interference,inhibition array technology miRSponge
URS0000508C13 HERPUD1 15685193 25416803 mrna cleavage,inhibition array technology,array technology,experimental interaction detection TarBase
URS0000237AF9 HERPUD1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00000ED600 HERPUD1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 HERPUD1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 HERPUD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 HERPUD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000037E170 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000043C1C3 HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 HERPUD1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC4BD HERPUD1 23592263 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS0000486E0B HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000021202F HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CCD18 HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075CC78 HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075D814 HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001012BC HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA HERPUD1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DERL1 HERPUD1 25361965 interaction type N/A PTMCode2
HERPUD1 DERL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VCP HERPUD1 25348397 N/A physical interaction ComPPI
DERL2 HERPUD1 25348397 N/A physical interaction ComPPI
USP7 HERPUD1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ARHGDIA HERPUD1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIAH1 HERPUD1 25348397 N/A physical interaction ComPPI
UBB HERPUD1 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI
UBC HERPUD1 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,physical interaction,comigration in sds page ComPPI
RPS27A HERPUD1 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI
UBA52 HERPUD1 25348397 N/A anti tag coimmunoprecipitation,covalent binding,physical interaction,comigration in sds page ComPPI
XRCC6 HERPUD1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EWSR1 HERPUD1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RPA2 HERPUD1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SYVN1 HERPUD1 16289116 21149444 23867461 25348397 26424800 26471130 27898060 N/A physical interaction ComPPI,OmniPath
UBQLN2 HERPUD1 14525934 18307982 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
CD3D HERPUD1 14525934 18307982 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBQLN4 HERPUD1 25348397 N/A physical interaction ComPPI
SNCAIP HERPUD1 25348397 N/A physical interaction ComPPI
PSMD2 HERPUD1 25348397 N/A physical interaction ComPPI
TOLLIP HERPUD1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SH3RF1 HERPUD1 25348397 N/A physical interaction ComPPI
SNCA HERPUD1 25348397 N/A physical interaction ComPPI
TRIM25 HERPUD1 25348397 N/A physical interaction ComPPI
TBK1 HERPUD1 25348397 N/A physical interaction ComPPI
UBQLN1 HERPUD1 25348397 N/A physical interaction ComPPI
AMFR HERPUD1 19223579 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
SELENOS HERPUD1 25348397 N/A physical interaction ComPPI
DERL1 HERPUD1 25348397 N/A physical interaction ComPPI
IL23A HERPUD1 25348397 N/A physical interaction ComPPI
PSEN1 HERPUD1 11799129 14525934 14550564 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
HERPUD1 CD58 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HERPUD1 STARD9 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HERPUD1 IMPA2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HERPUD1 IL1R1 25348397 N/A physical interaction ComPPI
HERPUD1 APP 25348397 N/A physical interaction ComPPI
HERPUD1 CAPN15 25348397 N/A physical interaction ComPPI
HERPUD1 ATG9A 25348397 N/A physical interaction ComPPI
HERPUD1 SEL1L 25348397 N/A physical interaction ComPPI
HERPUD1 FAM8A1 25348397 N/A physical interaction ComPPI
HERPUD1 UBXN6 18656546 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
C5AR2 HERPUD1 24234451 28298427 physical association ubiquitin reconstruction IntAct
CCR2 HERPUD1 24234451 28298427 physical association ubiquitin reconstruction IntAct
F2RL1 HERPUD1 24234451 28298427 physical association ubiquitin reconstruction IntAct
CHRM2 HERPUD1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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