GENE：HIP1R
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | HIP1R |
| FullNmae | huntingtin interacting protein 1 related |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18415 |
| EnsembleID | ENSG00000130787 |
| Uniprot | O75146 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| HIP1R | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| HIP1R | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| HIP1R | GO:0005515,GO:0005546,GO:0005547,GO:0005739,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0005905,GO:0005938,GO:0006897,GO:0006898,GO:0006919,GO:0006919,GO:0007015,GO:0014069,GO:0016324,GO:0017124,GO:0030100,GO:0030100,GO:0030136,GO:0030136,GO:0030276,GO:0030665,GO:0030837,GO:0032051,GO:0032092,GO:0032587,GO:0032839,GO:0032956,GO:0034316,GO:0035091,GO:0035615,GO:0042802,GO:0042803,GO:0043025,GO:0043065,GO:0043066,GO:0043197,GO:0043231,GO:0043325,GO:0043325,GO:0045742,GO:0046982,GO:0048268,GO:0048471,GO:0050821,GO:0051015,GO:0051015,GO:0055123,GO:0060453,GO:0080025,GO:0080025,GO:0097060,GO:0098978,GO:0099173,GO:1901030,GO:1905445,GO:2000369,GO:2000588 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | HIP1R | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | HIP1R | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | HIP1R | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | HIP1R | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | HIP1R | 23884370 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | HIP1R | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000077AED | HIP1R | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CC864 | HIP1R | 25416803 26898757 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| URS0000330617 | HIP1R | 25416803 26898757 | mrna cleavage,inhibition | miRNA interference luciferase reporter assay | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CLTA | HIP1R | 25361965 | interaction type | N/A | PTMCode2 |
| HIP1R | CLTA | 25361965 | interaction type | N/A | PTMCode2 |
| HIP1R | CLTC | 25361965 | interaction type | N/A | PTMCode2 |
| CLTC | HIP1R | 25361965 | interaction type | N/A | PTMCode2 |
| HIP1R | CTTN | 25361965 | interaction type | N/A | PTMCode2 |
| CTTN | HIP1R | 25361965 | interaction type | N/A | PTMCode2 |
| HIP1R | HIP1 | 25361965 | interaction type | N/A | PTMCode2 |
| HIP1 | HIP1R | 25361965 | interaction type | N/A | PTMCode2 |
| HIP1R | HTT | 25361965 | interaction type | N/A | PTMCode2 |
| HTT | HIP1R | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNW1 | HIP1R | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CDC5L | HIP1R | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| RALBP1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| SH3KBP1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| VCP | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| ACTB | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| TUFM | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| CRKL | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| CD81 | HIP1R | 24234451 25348397 26212323 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SFPQ | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| PPM1A | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| UBE2N | HIP1R | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| NTRK1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| PICALM | HIP1R | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NDRG1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| REPS1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| EPHA1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| CLTC | HIP1R | 11889126 14525934 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction | ComPPI,HPRD,IntAct |
| AP1B1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| CD70 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| TSG101 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| VCAM1 | HIP1R | 22623428 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| ITGA4 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| TRAF4 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| APLNR | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| PPM1B | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| UBA1 | HIP1R | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| CD274 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| GAK | HIP1R | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HIP1 | HIP1R | 11063258 11889126 14525934 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| VPS28 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| UBE2V1 | HIP1R | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| STAMBPL1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| CLTB | HIP1R | 11889126 1189126 14525934 15533940 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| BOP1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| MTMR6 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| RTRAF | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| LYPD3 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| MYH9 | HIP1R | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| WARS1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| PSPC1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| LIMA1 | HIP1R | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| IRF2BP1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| IL13RA2 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| FN1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| CAPZA2 | HIP1R | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| GART | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| SARS1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | TMEM171 | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | TEX29 | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | SCN2B | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | CEP41 | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | TATDN1 | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | GTSE1 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HIP1R | MYO19 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| HIP1R | FAM234B | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | SLC39A9 | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | MFSD4A | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | SLC15A1 | 25348397 | N/A | physical interaction | ComPPI |
| COMTD1 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| LRFN4 | HIP1R | 25348397 | N/A | physical interaction | ComPPI |
| HIP1R | DYNLL1 | 14525934 14760703 | N/A | experimental interaction detection | HPRD |
| HIP1R | CLTA | 11889126 14525934 15533940 | N/A | experimental interaction detection,two hybrid | HPRD |
| HIP1R | ACTA1 | 11889126 14525934 | N/A | experimental interaction detection | HPRD |
| HIP1R | HIP1R | 14525934 15533940 16415883 24234451 | N/A | molecular sieving,pull down,two hybrid | HPRD,IntAct |
| CTTN | HIP1R | 14525934 17318189 | N/A | experimental interaction detection | HPRD |
| HIP1R | HTT | 11063258 14525934 | N/A | experimental interaction detection | HPRD |