Gene Information gene info

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GENE：HYOU1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HYOU1
FullNmae hypoxia up-regulated 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16931
EnsembleID ENSG00000149428
Uniprot Q9Y4L1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HYOU1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HYOU1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
HYOU1 GO:0000774,GO:0002931,GO:0005515,GO:0005524,GO:0005576,GO:0005783,GO:0005788,GO:0005790,GO:0005925,GO:0006457,GO:0006888,GO:0016020,GO:0034663,GO:0034976,GO:0051082,GO:0070062,GO:0071456,GO:0071456,GO:0071682,GO:0140662,GO:1903298,GO:1903298,GO:1903382

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HYOU1 hsa:10525 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SARM1 HYOU1 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
EZH2 HYOU1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 HYOU1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HYOU1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC HYOU1 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
YBX1 HYOU1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF HYOU1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HYOU1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HYOU1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 HYOU1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HYOU1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HYOU1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXO1 HYOU1 21296878 trascriptional regulation,stimulation inferred by curator TFlink
SIRT1 HYOU1 22564731 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 HYOU1 20304954 23622248 25416803 mrna cleavage,inhibition array technology,clash TarBase
URS0000237AF9 HYOU1 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000002103A HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AD002 HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001012BC HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000345DEB HYOU1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000192A75 HYOU1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000512C88 HYOU1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C HYOU1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000022AAA HYOU1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D HYOU1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C HYOU1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 HYOU1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 HYOU1 25416803 28276476 mrna cleavage,inhibition array technology,western blot,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
GOLGA2 HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
HSPA8 HYOU1 25348397 N/A physical interaction ComPPI
SGTB HYOU1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HK2 HYOU1 25348397 N/A physical interaction ComPPI
TRAF6 HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
GABARAPL2 HYOU1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MCM2 HYOU1 25348397 N/A physical interaction ComPPI
EZH2 HYOU1 25348397 N/A physical interaction ComPPI
PTPRO HYOU1 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
JUN HYOU1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
CLU HYOU1 25348397 N/A physical interaction ComPPI
DLD HYOU1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 HYOU1 25348397 N/A physical interaction ComPPI
CANX HYOU1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
XRCC5 HYOU1 25348397 N/A physical interaction ComPPI
HSPA5 HYOU1 24234451 25348397 26496610 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction ComPPI,IntAct
MSH6 HYOU1 25348397 N/A physical interaction ComPPI
GBA HYOU1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA1 HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
XRCC6 HYOU1 25348397 N/A physical interaction ComPPI
DCTN1 HYOU1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CFTR HYOU1 25348397 N/A physical interaction ComPPI
NPHP1 HYOU1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EWSR1 HYOU1 25348397 N/A physical interaction ComPPI
DNAJC7 HYOU1 25348397 N/A physical interaction ComPPI
ARF6 HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
BIN1 HYOU1 25348397 N/A physical interaction ComPPI
CDK2 HYOU1 25348397 N/A physical interaction ComPPI
EGFR HYOU1 25348397 N/A physical interaction ComPPI
TUBA1A HYOU1 24234451 25348397 29568061 association pull down ComPPI,IntAct
SCNN1A HYOU1 25348397 N/A physical interaction ComPPI
NAPA HYOU1 25348397 N/A physical interaction ComPPI
RAB11A HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
VHL HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RNF2 HYOU1 25348397 N/A physical interaction ComPPI
YAP1 HYOU1 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KIF13A HYOU1 25348397 N/A physical interaction ComPPI
RAB9A HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CUL7 HYOU1 25348397 N/A physical interaction ComPPI
ETF1 HYOU1 25348397 N/A physical interaction ComPPI
PTPRN HYOU1 25348397 N/A physical interaction ComPPI
SGK1 HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DNAJB11 HYOU1 25348397 N/A physical interaction ComPPI
OS9 HYOU1 25348397 N/A physical interaction ComPPI
H2AX HYOU1 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ESR1 HYOU1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
DNAJB1 HYOU1 25348397 N/A physical interaction ComPPI
ESR2 HYOU1 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
BRCA1 HYOU1 25348397 N/A physical interaction ComPPI
GANAB HYOU1 25348397 N/A physical interaction ComPPI
TGOLN2 HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
DNAJA1 HYOU1 25348397 N/A physical interaction ComPPI
AURKB HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CNTRL HYOU1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TNFRSF10D HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKE HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
NUP37 HYOU1 25348397 N/A physical interaction ComPPI
NUP205 HYOU1 25348397 N/A physical interaction ComPPI
MCM7 HYOU1 25348397 N/A physical interaction ComPPI
DLST HYOU1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
MCC HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HK1 HYOU1 25348397 N/A physical interaction ComPPI
DNAJB4 HYOU1 25348397 N/A physical interaction ComPPI
COX4I1 HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CZIB HYOU1 25348397 N/A physical interaction ComPPI
ARMCX3 HYOU1 25348397 N/A physical interaction ComPPI
PLGRKT HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MGST3 HYOU1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
OFD1 HYOU1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SIRT7 HYOU1 25348397 N/A physical interaction ComPPI
DNAJC2 HYOU1 25348397 N/A physical interaction ComPPI
FBXO6 HYOU1 25348397 N/A physical interaction ComPPI
EXT2 HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
LAMP1 HYOU1 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
BCAR1 HYOU1 24234451 25348397 28007913 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR1C HYOU1 25348397 N/A physical interaction ComPPI
FBF1 HYOU1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NXF1 HYOU1 25348397 N/A physical interaction ComPPI
MOV10 HYOU1 25348397 N/A physical interaction ComPPI
HLA-A HYOU1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HYOU1 SARM1 25348397 N/A physical interaction ComPPI
HYOU1 ATP6V1F 25348397 N/A physical interaction ComPPI
HYOU1 DNAJA4 25348397 N/A physical interaction ComPPI
HYOU1 DNAJB5 25348397 N/A physical interaction ComPPI
HYOU1 DNAJC17 25348397 N/A physical interaction ComPPI
HYOU1 DNAJC3 25348397 N/A physical interaction ComPPI
HYOU1 DNAJC8 25348397 N/A physical interaction ComPPI
HYOU1 DNAJC9 25348397 N/A physical interaction ComPPI
HYOU1 SEL1L 25348397 N/A physical interaction ComPPI
HYOU1 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HYOU1 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HYOU1 TCTN1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HYOU1 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HYOU1 RFWD3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HYOU1 EDEM3 25348397 N/A physical interaction ComPPI
HYOU1 COX14 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ATP6V1B2 HYOU1 25348397 N/A physical interaction ComPPI
ATF4 HYOU1 24234451 26700459 association chromatin immunoprecipitation assay IntAct
NFE2L2 HYOU1 24234451 26700459 association chromatin immunoprecipitation assay IntAct
SMARCB1 HYOU1 24234451 30108113 association pull down,proximity-dependent biotin identification IntAct
RPL7 HYOU1 24234451 30021884 physical association cross-linking study IntAct
HYOU1 CCDC39 24234451 30021884 physical association cross-linking study IntAct
HYOU1 CCDC138 24234451 30021884 physical association cross-linking study IntAct
HYOU1 ZNF786 24234451 30021884 physical association cross-linking study IntAct
HYOU1 ZNF521 24234451 30021884 physical association cross-linking study IntAct
HYOU1 DAPK1 24234451 30021884 physical association cross-linking study IntAct
HYOU1 EPS15L1 24234451 30021884 physical association cross-linking study IntAct
SEC61A1 HYOU1 12065409 24218449 27898060 N/A N/A OmniPath

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