Gene Information gene info

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GENE：IFI27

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IFI27
FullNmae interferon alpha inducible protein 27
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5397
EnsembleID ENSG00000165949
Uniprot P40305

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IFI27 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IFI27 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
IFI27 GO:0000122,GO:0003674,GO:0005515,GO:0005521,GO:0005635,GO:0005637,GO:0005739,GO:0005739,GO:0005741,GO:0005789,GO:0006915,GO:0031966,GO:0042802,GO:0043161,GO:0044827,GO:0045087,GO:0046825,GO:0051607,GO:0060090,GO:0060337,GO:0061629,GO:0070269,GO:0070936,GO:0097190,GO:0097191

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IFI27 STAT1 16195385 23180781 23386060 physical association anti tag coimmunoprecipitation InnateDB
IFI27 STAT2 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB
IFI27 IRF9 16195385 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
FOXO3 IFI27 17522055 trascriptional regulation,stimulation chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
FOXA1 IFI27 16331276 18971253 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
VDR IFI27 16518840 trascriptional regulation,stimulation chromatin immunoprecipitation assay,electrophoretic mobility shift assay TFlink
MITF IFI27 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 IFI27 18155131 18413744 18417445 \N rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000153377 IFI27 18413744 18417445 \N rna interference,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001EFBE3 IFI27 18057241 25416803 mrna cleavage,inhibition array technology TarBase
URS00005194EC IFI27 24727952 24970806 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000544FF1 IFI27 25103640 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDK4 IFI27 25361965 interaction type N/A PTMCode2
IFI27 CDK4 25361965 interaction type N/A PTMCode2
CCND1 IFI27 25361965 interaction type N/A PTMCode2
IFI27 CCND1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CCND1 IFI27 14525934 25348397 9837900 N/A experimental interaction detection,in vivo ComPPI,HPRD
IFI27 CDK4 14525934 25348397 9837900 N/A experimental interaction detection,in vivo ComPPI,HPRD
IFI27 SKP2 25348397 N/A physical interaction ComPPI
TFAP2C IFI27 24234451 24835590 25348397 physical association two hybrid ComPPI,IntAct
APOC4 IFI27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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