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GENE：IL19

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL19
FullNmae interleukin 19
LocusType gene with protein product
Status Approved
HGNC_id HGNC:5990
EnsembleID ENSG00000142224
Uniprot Q9UHD0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL19 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IL19 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
IL19 GO:0005125,GO:0005576,GO:0005576,GO:0005615,GO:0006915,GO:0006955,GO:0007165,GO:0010989,GO:0072593,GO:2001237,GO:2001244

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL19 hsa:29949 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL19 hsa:29949 path:hsa04061 Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)
IL19 hsa:29949 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RUNX1T1 IL19 16631120 23180781 physical association pull down InnateDB
IL20RB IL19 14580208 23180781 physical association molecular sieving InnateDB
STAT6 IL19 18539194 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL19 IL20RA 11564763 17208301 18988627 23331499 stimulation N/A SignaLink,SignaLink
IL19 IL20RB 17208301 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR IL19 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 IL19 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 IL19 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 IL19 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 IL19 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 IL19 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 IL19 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IL19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA IL19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IL19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 IL19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF IL19 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 IL19 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
IL20RA IL19 25348397 N/A in vivo ComPPI
IL19 IL20RA 11564763 172083 27898060 stimulant N/A OmniPath
IL19 IL20RB 14580208 17208301 27898060 stimulant N/A OmniPath

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