Gene Information gene info

GENE:ING5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ING5
FullNmae inhibitor of growth family member 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19421
EnsembleID ENSG00000168395
Uniprot Q8WYH8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ING5 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ING5 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ING5 GO:0000123,GO:0000123,GO:0001558,GO:0001558,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006275,GO:0006355,GO:0006355,GO:0006355,GO:0006473,GO:0008285,GO:0008285,GO:0035064,GO:0035064,GO:0043065,GO:0045926,GO:0046872,GO:0048144,GO:0048147,GO:0050793,GO:0051726,GO:0070776,GO:0070776,GO:0097190,GO:0140889,GO:1903706,GO:2000278,GO:2001235

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 ING5 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
SMARCA4 ING5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ING5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ING5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ING5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ING5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ING5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
BRPF1 ING5 18794358 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000076B539 ING5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDA4 ING5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004D84DB ING5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB ING5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00005F1B8C ING5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000105D19 ING5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B ING5 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC ING5 25416803 26497554 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,immunohistochemistry,miRNA interference luciferase reporter assay TarBase
URS0000367985 ING5 25416803 25991669 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 ING5 22135298 phosphorylation N/A PhosphoSite
TP53 ING5 25361965 interaction type N/A PTMCode2
ING5 TP53 25361965 interaction type N/A PTMCode2
MCM6 ING5 25361965 interaction type N/A PTMCode2
ING5 MCM6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SMARCE1 ING5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
JADE3 ING5 25348397 N/A physical interaction ComPPI
VIM ING5 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CDKN1A ING5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KRTAP10-7 ING5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GCSH ING5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM6 ING5 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MCM2 ING5 25348397 N/A physical interaction ComPPI
KRT40 ING5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
C3ORF62 ING5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KXD1 ING5 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach ComPPI,IntAct
NAV2 ING5 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
EP300 ING5 12750254 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HGS ING5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
APC ING5 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PARP2 ING5 21812934 24234451 25348397 adp ribosylation reaction protein array ComPPI,IntAct
WASF1 ING5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRMT5 ING5 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CTR9 ING5 25348397 N/A physical interaction ComPPI
TADA3 ING5 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
HTT ING5 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
IKZF3 ING5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BRD1 ING5 25348397 N/A physical interaction ComPPI
ING5 HAP1 25348397 N/A two hybrid,physical interaction ComPPI
ING5 BARD1 14525934 15383276 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
ING5 CEP126 15383276 24234451 25348397 physical association two hybrid ComPPI,IntAct
ING5 PCM1 16189514 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ING5 TP53 12750254 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ING5 KAT7 25348397 N/A physical interaction ComPPI
ING5 KAT6A 25348397 N/A physical interaction ComPPI
ING5 KAT6B 25348397 N/A physical interaction ComPPI
ING5 BRPF3 25348397 N/A physical interaction ComPPI
ING5 JADE1 25348397 N/A physical interaction ComPPI
ING5 JADE2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ING5 MEAF6 25348397 N/A physical interaction ComPPI
ING5 BRPF1 25348397 N/A physical interaction ComPPI
ING5 MCM4 25348397 N/A physical interaction ComPPI
ING5 MEST 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ING5 APLP1 25348397 N/A physical interaction ComPPI
ING5 ICA1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ING5 ARFIP2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ING5 MBIP 25348397 N/A physical interaction ComPPI
ING5 CDCA7L 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ING5 CCDC33 25348397 N/A physical interaction ComPPI
ING5 CEP44 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ING5 DEUP1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ING5 MOV10 25348397 N/A physical interaction ComPPI
ING5 NXF1 25348397 N/A physical interaction ComPPI
ING5 NEDD1 25348397 N/A physical interaction ComPPI
ING5 TRIM25 25348397 N/A physical interaction ComPPI
ING5 THAP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ING5 GRIPAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ING5 TRIML2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ING5 SUOX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ING5 BEX3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TAF1D ING5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FAM118B ING5 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ING5 INCA1 21750715 24234451 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down IntAct
H2BC9 ING5 24234451 30021884 physical association cross-linking study IntAct
CDK2 ING5 25860957 27898060 N/A N/A OmniPath

Visualization