Gene Information gene info

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GENE：ITM2C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ITM2C
FullNmae integral membrane protein 2C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6175
EnsembleID ENSG00000135916
Uniprot Q9NQX7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ITM2C apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ITM2C apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ITM2C GO:0001540,GO:0001540,GO:0005515,GO:0005524,GO:0005764,GO:0005765,GO:0005794,GO:0005794,GO:0005886,GO:0005886,GO:0010977,GO:0030182,GO:0042985,GO:0048471,GO:0070062,GO:2001238

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 ITM2C 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB
ITM2C POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ITM2C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ITM2C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ITM2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ITM2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ITM2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ITM2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D ITM2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E ITM2C 20371350 21572407 23446348 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS000005481D ITM2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001A7A ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015A0D9 ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000235862 ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000009A9A2 ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000020579D ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A608 ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017CCCB ITM2C 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000A057E ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000012930C ITM2C 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003B6B84 ITM2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002367FA ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000081D1E ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001310DE ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006097A6 ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000076E54 ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002B0B46 ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D15B ITM2C 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FURIN ITM2C 25361965 interaction type N/A PTMCode2
ITM2C FURIN 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RNF7 ITM2C 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FURIN ITM2C 14525934 15606899 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CUL7 ITM2C 25348397 N/A physical interaction ComPPI
BACE1 ITM2C 14525934 15606899 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
BET1 ITM2C 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
ITM2C STT3A 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ITM2C MTNR1B 14525934 17215244 24234451 25348397 26514267 association experimental interaction detection,physical interaction,in vivo,tandem affinity purification ComPPI,HPRD,IntAct
ITM2C RYK 25348397 N/A physical interaction ComPPI
ITM2C MVB12B 25348397 N/A physical interaction ComPPI
ITM2C TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ITM2C TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FURIN ITM2C 15606899 27898060 N/A N/A OmniPath

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