GENE：ITPRIP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ITPRIP |
| FullNmae | inositol 1,4,5-trisphosphate receptor interacting protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:29370 |
| EnsembleID | ENSG00000148841 |
| Uniprot | Q8IWB1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ITPRIP | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ITPRIP | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ITPRIP | GO:0004860,GO:0005515,GO:0005640,GO:0005886,GO:0008625,GO:0016020,GO:0016020,GO:1902042 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ITPRIP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | ITPRIP | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ITPRIP | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ITPRIP | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ITPRIP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| NR1I2 | ITPRIP | 19129222 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | ITPRIP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | ITPRIP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | ITPRIP | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000065D58 | ITPRIP | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS00000DDD35 | ITPRIP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000023133F | ITPRIP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | ITPRIP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000020579D | ITPRIP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D50C | ITPRIP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000FC8EB | ITPRIP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | ITPRIP | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PLTP | ITPRIP | 25348397 | N/A | physical interaction | ComPPI |
| CACYBP | ITPRIP | 24234451 25036637 25348397 | physical association | luminescence based mammalian interactome mapping | ComPPI,IntAct |
| PSMC5 | ITPRIP | 25348397 | N/A | physical interaction | ComPPI |
| RASSF1 | ITPRIP | 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| TLR2 | ITPRIP | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | ITPRIP | 25348397 | N/A | physical interaction | ComPPI |
| CD79B | ITPRIP | 25348397 | N/A | physical interaction | ComPPI |
| ITPR1 | ITPRIP | 14525934 16990268 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| ITPRIP | FBXO6 | 25348397 | N/A | physical interaction | ComPPI |
| ITPRIP | MAS1 | 25348397 | N/A | physical interaction | ComPPI |