GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
MAGEA3
FullNmae
MAGE family member A3
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:6801
EnsembleID
ENSG00000221867
Uniprot
P43357
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
MAGEA3
apoptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
MAGEA3
apoptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
MAGEA3
GO:0000122,GO:0005515,GO:0005634,GO:0005783,GO:0010507,GO:0010955,GO:0042826,GO:0043154,GO:0089720,GO:1902236
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
MYC
MAGEA3
12695333
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS00000EED18
MAGEA3
21177782
rna interference,inhibition
western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay
miRSponge
URS00000EED18
MAGEA3
21177782
25416803
mrna cleavage,inhibition
western blot,quantitative reverse transcription pcr,immunocytochemistry,miRNA interference luciferase reporter assay
TarBase
URS0000324096
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000031E12
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00000A07C1
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000000B1C9
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000029979D
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000237CBD
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS00003D8730
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000001EB3
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000032EF64
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000272039
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS000031BC7D
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
URS0000122ED0
MAGEA3
25416803
27292025
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
EXOC5
MAGEA3
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
LSM2
MAGEA3
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
HK2
MAGEA3
25348397
N/A
physical interaction
ComPPI
POLL
MAGEA3
25348397
N/A
physical interaction
ComPPI
STAT5A
MAGEA3
25348397
N/A
physical interaction
ComPPI
ABI3
MAGEA3
25348397
N/A
physical interaction
ComPPI
HTT
MAGEA3
25348397
N/A
physical interaction
ComPPI
TRIM28
MAGEA3
20864041
21277283
24234451
25348397
physical association
two hybrid,pull down,physical interaction,tandem affinity purification
ComPPI,IntAct
RUSC1
MAGEA3
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
DNM1L
MAGEA3
18330356
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
NPPA
MAGEA3
25348397
N/A
physical interaction
ComPPI
STAMBPL1
MAGEA3
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
SCMH1
MAGEA3
25348397
N/A
physical interaction
ComPPI
HLA-DRB1
MAGEA3
25348397
N/A
physical interaction
ComPPI
PCYT1A
MAGEA3
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
S100A9
MAGEA3
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
MAGEA3
CLIP4
25348397
N/A
physical interaction
ComPPI
MAGEA3
BAP18
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
Visualization