Gene Information gene info

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GENE：MAL

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAL
FullNmae mal, T cell differentiation protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6817
EnsembleID ENSG00000172005
Uniprot P21145

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAL apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MAL GO:0001766,GO:0002175,GO:0005515,GO:0005783,GO:0006915,GO:0007417,GO:0008289,GO:0016324,GO:0016505,GO:0019911,GO:0019911,GO:0022010,GO:0030154,GO:0042552,GO:0042552,GO:0042552,GO:0043220,GO:0044853,GO:0045121,GO:0045176,GO:0098737,GO:0120003,GO:1902043

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MYD88 MAL 22485159 23180781 physical association pull down InnateDB
MAL TLR4 22485159 23180781 physical association pull down InnateDB
MAL MAL 22485159 23180781 physical association pull down InnateDB
MAL USP7 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
TFAP2C MAL 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MAL 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MAL 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SMIM3 MAL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NPDC1 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LMNA MAL 25348397 N/A physical interaction ComPPI
CD69 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SYNDIG1 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BTK MAL 22366891 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,pull down,confocal microscopy ComPPI,IntAct
SYK MAL 22366891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LYN MAL 22366891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PIK3R1 MAL 22366891 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
SRC MAL 22366891 24234451 25348397 colocalization,association anti bait coimmunoprecipitation,confocal microscopy ComPPI,IntAct
USP7 MAL 21988832 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
GJB1 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SDC4 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
STX1A MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CD3G MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AMHR2 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EDA MAL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MYD88 MAL 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
PTPRN MAL 25348397 N/A physical interaction ComPPI
SGCB MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GJA8 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFSF14 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLDN7 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KCNA10 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLSTN3 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLA2G10 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL20RB MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KCNA1 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CXADR MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCL2L13 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CREB3L1 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KLRC1 MAL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CD53 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTK2 MAL 22366891 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CLEC4C MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HIBADH MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM52B MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM207 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LRRC25 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LSMEM1 MAL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EVI2A MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM248 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TIGIT MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TMEM174 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GRAMD1A MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC10A1 MAL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL FIBCD1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAL LDLRAD1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAL PERP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL CLDN14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL TM4SF18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL CALN1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL KCNMB4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL LRTM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL EMP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL MS4A4A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL LMAN2L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL FNDC9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL GPR152 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL TSPO2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL FAM209A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL CLDN9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL DAGLA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL AQP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL TMEM106C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAL NKAIN4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MC4R MAL 24234451 28298427 physical association ubiquitin reconstruction IntAct
TLR4 MAL 22485159 27898060 N/A N/A OmniPath
MAL MYD88 21988832 22485159 27898060 stimulant N/A OmniPath

Visualization










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