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GENE：MAPK9

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAPK9
FullNmae mitogen-activated protein kinase 9
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6886
EnsembleID ENSG00000050748
Uniprot P45984

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAPK9 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAPK9 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAPK9 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAPK9 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAPK9 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MAPK9 GO:0004705,GO:0004705,GO:0004705,GO:0004712,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005829,GO:0005886,GO:0006468,GO:0007254,GO:0007254,GO:0010628,GO:0010744,GO:0016607,GO:0018105,GO:0031398,GO:0032436,GO:0034614,GO:0038095,GO:0042752,GO:0048511,GO:0050804,GO:0061833,GO:0071276,GO:0071803,GO:0090398,GO:0090594,GO:0097190,GO:0098685,GO:0106310,GO:1900017,GO:2001235

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MAPK9 hsa:5601 path:hsa01522 Endocrine resistance - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04024 cAMP signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04068 FoxO signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04137 Mitophagy - animal - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04140 Autophagy - animal - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04210 Apoptosis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04215 Apoptosis - multiple species - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04217 Necroptosis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04310 Wnt signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04510 Focal adhesion - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04530 Tight junction - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04620 Toll-like receptor signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04621 NOD-like receptor signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04622 RIG-I-like receptor signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04657 IL-17 signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04658 Th1 and Th2 cell differentiation - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04668 TNF signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04722 Neurotrophin signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04728 Dopaminergic synapse - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04750 Inflammatory mediator regulation of TRP channels - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04912 GnRH signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04914 Progesterone-mediated oocyte maturation - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04917 Prolactin signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04920 Adipocytokine signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04930 Type II diabetes mellitus - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04931 Insulin resistance - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04932 Non-alcoholic fatty liver disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04935 Growth hormone synthesis, secretion and action - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05010 Alzheimer disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05012 Parkinson disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05016 Huntington disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05017 Spinocerebellar ataxia - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05020 Prion disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05120 Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05131 Shigellosis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05132 Salmonella infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05133 Pertussis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05135 Yersinia infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05142 Chagas disease - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05152 Tuberculosis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05161 Hepatitis B - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05162 Measles - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05200 Pathways in cancer - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05210 Colorectal cancer - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05212 Pancreatic cancer - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05231 Choline metabolism in cancer - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)
MAPK9 hsa:5601 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MAP2K4 MAPK9 11062067 11242034 12788955 14699111 18988627 23180781 23331499 9841871 phosphorylation reaction,stimulation,physical association gst pull down,in-gel kinase assay InnateDB,SignaLink,SignaLink
MAPK9 MAPKAP1 15722200 23180781 physical association gst pull down InnateDB
ELK1 MAPK9 23180781 8654373 8846788 phosphorylation reaction,physical association gst pull down,in-gel kinase assay InnateDB
MAPK9 JUN 11278395 17189706 23180781 8001819 8654373 phosphorylation reaction,physical association gst pull down,in-gel kinase assay InnateDB
TP53 MAPK9 11283254 23180781 phosphorylation reaction in-gel kinase assay InnateDB
SELE MAPK9 23180781 9006914 physical association affinity chromatography technology InnateDB
MAPK8IP1 MAPK9 15998799 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
CASP3 MAPK9 12821118 23180781 cleavage reaction cleavage reaction InnateDB
MAP3K10 MAPK9 11278395 23180781 phosphorylation reaction in-gel kinase assay InnateDB
MAPK9 BCL10 17189706 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK9 MALT1 17189706 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFATC4 MAPK9 17875713 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,in-gel kinase assay InnateDB
MAPK9 ATF2 15192015 23180781 8654373 phosphorylation reaction,physical association gst pull down,in-gel kinase assay,protein kinase assay InnateDB
RARG MAPK9 10383391 23180781 physical association gst pull down InnateDB
RARA MAPK9 10383391 23180781 physical association gst pull down InnateDB
DUSP16 MAPK9 11359773 14699111 23180781 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
DUSP1 MAPK9 11359773 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK9 DUSP10 11359773 23180781 physical association anti tag coimmunoprecipitation InnateDB
MAPK9 MCL1 17670986 23180781 phosphorylation reaction in-gel kinase assay InnateDB
MAPK9 IRF3 19153595 23180781 phosphorylation reaction in-gel kinase assay InnateDB
WDR62 MAPK9 19910486 23180781 physical association anti tag coimmunoprecipitation InnateDB
CTNNB1 MAPK9 19667122 23180781 phosphorylation reaction protein kinase assay InnateDB
STAB2 MAPK9 18387958 23180781 physical association anti tag coimmunoprecipitation InnateDB
NFE2 MAPK9 19966288 23180781 physical association affinity chromatography technology InnateDB
ARRB1 MAPK9 23180781 25416956 physical association two hybrid InnateDB
ARRB2 MAPK9 23180781 25416956 physical association two hybrid InnateDB
MAP2K7 MAPK9 11242024 23331499 stimulation N/A SignaLink,SignaLink
MAPK9 CTNNB1 19623618 23331499 stimulation N/A SignaLink,SignaLink
MAPK8IP2 MAPK9 10490659 15767678 23331499 stimulation N/A SignaLink
MAPK8IP3 MAPK9 10523642 10629060 11024282 12189133 15767678 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ARRB2 MAPK9 20005715 interaction type N/A PSP,SignaLink
GRB2 MAPK9 20005715 interaction type N/A PSP,SignaLink
IRS1 MAPK9 20005715 interaction type N/A PSP
MAPK8IP1 MAPK9 20005715 interaction type N/A PSP
MAPK8IP2 MAPK9 20005715 interaction type N/A PSP
MAPK8IP3 MAPK9 20005715 interaction type N/A PSP
MAPKBP1 MAPK9 20005715 interaction type N/A PSP
SH3BP5 MAPK9 20005715 interaction type N/A PSP
TOB1 MAPK9 12151396 20005715 21071413 interaction type N/A PSP,SignaLink
TRAF2 MAPK9 20005715 interaction type N/A PSP
MAPK8IP1 MAPK9 10490659 10490659 10490659 18988627 20005715 20005715 21071413 N/A N/A SignaLink
MAPK8IP2 MAPK9 20005715 20005715 N/A N/A SignaLink
MAPK8IP3 MAPK9 20005715 20005715 N/A N/A SignaLink
IRS1 MAPK9 20005715 20005715 N/A N/A SignaLink
MAPKBP1 MAPK9 10471813 18988627 20005715 20005715 N/A N/A SignaLink
SH3BP5 MAPK9 20005715 20005715 N/A N/A SignaLink
TRAF2 MAPK9 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
E2F4 MAPK9 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
GATA2 MAPK9 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MAPK9 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C MAPK9 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MAPK9 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MAPK9 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 MAPK9 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000003E1A9 MAPK9 20053927 rna interference,inhibition western blot miRSponge
URS00002075FA MAPK9 18700987 21283765 rna interference,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000042E1F MAPK9 21283765 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000DDD35 MAPK9 20065103 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000DDD35 MAPK9 20065103 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00002075FA MAPK9 18700987 21283765 23029228 25416803 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000042E1F MAPK9 21283765 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000600E6 MAPK9 21283765 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS000003E1A9 MAPK9 20053927 25416803 mrna cleavage,inhibition western blot TarBase
URS00000F31F4 MAPK9 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MAPK9 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000330617 MAPK9 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002B3783 MAPK9 23029228 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000039E1E1 MAPK9 23029228 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00003B59DF MAPK9 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB MAPK9 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MAPK9 22135298 phosphorylation N/A PhosphoSite
MAP2K7 MAPK9 22135298 phosphorylation N/A PhosphoSite
MAP2K4 MAPK9 22135298 phosphorylation N/A PhosphoSite
MAPK9 ATF2 22135298 phosphorylation N/A PhosphoSite
MAPK9 MYC 22135298 phosphorylation N/A PhosphoSite
MAPK9 PSEN1 22135298 phosphorylation N/A PhosphoSite
MAPK9 RXRA 22135298 phosphorylation N/A PhosphoSite
MAPK9 JDP2 22135298 phosphorylation N/A PhosphoSite
MAPK9 TOB1 22135298 phosphorylation N/A PhosphoSite
MAPK9 BCL2L1 22135298 phosphorylation N/A PhosphoSite
MAPK9 NFATC4 22135298 phosphorylation N/A PhosphoSite
MAPK9 PDX1 22135298 phosphorylation N/A PhosphoSite
MAPK9 NFATC3 22135298 phosphorylation N/A PhosphoSite
MAPK9 JUN 22135298 phosphorylation N/A PhosphoSite
MAPK9 BAZ1B 22135298 phosphorylation N/A PhosphoSite
MAPK9 CDC25C 22135298 phosphorylation N/A PhosphoSite
MAPK9 SLC6A4 22135298 phosphorylation N/A PhosphoSite
MAPK9 TP53 22135298 phosphorylation N/A PhosphoSite
MAPK9 BID 22135298 phosphorylation N/A PhosphoSite
MAPK9 MAPKAPK5 22135298 phosphorylation N/A PhosphoSite
MAPK9 MARCKS 22135298 phosphorylation N/A PhosphoSite
MAPK9 MAPK8IP1 22135298 phosphorylation N/A PhosphoSite
MAPK9 FOXO4 22135298 phosphorylation N/A PhosphoSite
MAPK9 RRN3 22135298 phosphorylation N/A PhosphoSite
MAPK9 GORASP1 22135298 phosphorylation N/A PhosphoSite
MAPK9 APLP2 22135298 phosphorylation N/A PhosphoSite
RET MAPK9 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
MAPK9 SMCO3 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 SF3B4 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
MAPK9 JUN 14525934 19527717 24234451 25348397 9405416 phosphorylation reaction experimental interaction detection,physical interaction,biochemical,protein kinase assay,in vitro ComPPI,HPRD,IntAct
MAPK9 JUND 14525934 25348397 8945519 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPK9 ELK1 14525934 25348397 8548291 9130707 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK9 ELK3 11042694 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK9 H3-3A 11278789 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK9 MAP2K4 11062067 14525934 21900206 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
MAPK9 TRAF2 10490605 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vitro,proximity ligation assay ComPPI,HPRD,IntAct
MAPK9 MAP2K7 25348397 N/A physical interaction,in vitro,in vivo ComPPI
MAPK9 BCL2L11 12818176 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK9 PRKD1 11948398 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK9 ATF7 25348397 N/A in vitro,in vivo ComPPI
MAPK9 EEF2K 12171600 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK9 MAPKAPK5 14525934 24234451 25241761 25348397 9628874 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
MAPK9 DUSP16 11359773 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
MAPK9 MAPK8IP3 10523642 10629060 11024282 12189133 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK9 SH3BP5 12167088 14525934 15158451 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MAPK9 DUSP19 11959861 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
MAPK9 JDP2 11602244 12225289 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK9 MAPKBP1 10471813 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
MAPK9 DUSP4 14525934 24234451 25241761 25348397 8626452 physical association experimental interaction detection,physical interaction,two hybrid array,in vivo,proximity ligation assay,two hybrid prey pooling approach ComPPI,HPRD,IntAct
MAPK9 ZBTB25 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAPK9 WDR62 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
MAPK9 CEP44 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
MAPK9 CEP126 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MAPK9 SMAD2 14525934 15326485 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK9 SMAD3 14525934 15326485 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK9 ATF2 12110590 12788955 14525934 24234451 25348397 25416956 602896 7737129 physical association experimental interaction detection,physical interaction,two hybrid array,protein kinase assay,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
MAPK9 RB1 11566021 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAPK9 ACP5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAPK9 XPNPEP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MAPK9 XPO7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MAPK9 RPS6KB1 11279232 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK9 MAPK8IP1 10490659 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK9 MAPK8IP2 10490659 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MAPK9 HSF1 11527157 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAPK9 IRS1 12417588 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAPK9 DUSP1 25348397 N/A physical interaction ComPPI
MAPK9 DUSP10 16288922 24234451 25348397 dephosphorylation reaction,physical association physical interaction,two hybrid array,phosphatase assay,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 PRKDC 25348397 N/A physical interaction ComPPI
MAPK9 TP53 14525934 25348397 9393873 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MAPK9 JUNB 25348397 N/A physical interaction ComPPI
MAPK9 TOB1 25348397 N/A physical interaction ComPPI
MAPK9 GRB2 25348397 N/A physical interaction ComPPI
MAPK9 MACF1 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
MAPK9 HDAC9 25348397 N/A physical interaction ComPPI
MAPK9 HDAC1 25348397 N/A physical interaction ComPPI
MAPK9 NFATC2 25348397 N/A physical interaction ComPPI
MAPK9 MFN2 25348397 N/A physical interaction ComPPI
MAPK9 MAP3K1 25348397 N/A physical interaction ComPPI
MAPK9 CTNNB1 25348397 N/A physical interaction ComPPI
MAPK9 STK25 25348397 N/A physical interaction ComPPI
MAPK9 PKN1 25348397 N/A physical interaction ComPPI
MAPK9 HMGCS1 25348397 N/A physical interaction ComPPI
MAPK9 BCL10 25348397 N/A physical interaction ComPPI
MAPK9 IRF3 25348397 N/A physical interaction ComPPI
MAPK9 NFATC4 25348397 N/A physical interaction ComPPI
MAPK9 NFATC3 14525934 25348397 9374467 N/A experimental interaction detection,physical interaction ComPPI,HPRD
MAPK9 CASP3 25348397 N/A physical interaction ComPPI
MAPK9 ARRB2 19060904 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 MAP3K10 25348397 N/A physical interaction ComPPI
MAPK9 CDC25C 25348397 N/A physical interaction ComPPI
MAPK9 NCF1B 25348397 N/A physical interaction ComPPI
MAPK9 NCF1 25348397 N/A physical interaction ComPPI
MAPK9 CDC25B 25348397 N/A physical interaction ComPPI
MAPK9 CLU 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK9 SSU72 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK9 ARRB1 21988832 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 LMAN2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK9 TUSC2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK9 CYHR1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAPK9 MAPK10 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 MAPK8 23602568 24234451 25284480 25348397 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 DUSP8 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 SPTAN1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 LAMA1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 FTH1 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MAPK9 SEC13 25348397 N/A physical interaction ComPPI
MAPK9 DHX33 25348397 N/A physical interaction ComPPI
MAPK9 NFE2L2 25348397 N/A physical interaction ComPPI
MAPK9 CTBP1 25348397 N/A physical interaction ComPPI
MAPK9 MEOX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 SHMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 TEX11 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 CCDC33 25348397 N/A physical interaction ComPPI
MAPK9 EFHC2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 L3MBTL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 LNX1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 C1ORF94 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MAPK9 EGFR 24234451 24658140 25348397 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
MAPK9 AKT1 25348397 N/A physical interaction ComPPI
MAPK9 DTX3 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 H1-5 25348397 N/A physical interaction ComPPI
MAPK9 SERPINB5 25348397 N/A physical interaction ComPPI
MAPK9 CSNK1E 25348397 N/A physical interaction ComPPI
MAPK9 DUSP14 25348397 N/A physical interaction ComPPI
MAPK9 PKP3 25348397 N/A physical interaction ComPPI
MAPK9 LRRC15 25348397 N/A physical interaction ComPPI
MAPK9 DSG4 25348397 N/A physical interaction ComPPI
MAPK9 VSIG8 25348397 N/A physical interaction ComPPI
MAPK9 PPM1A 25348397 N/A physical interaction ComPPI
MAPK9 STK26 25348397 N/A physical interaction ComPPI
MAPK9 CDT1 25348397 N/A physical interaction ComPPI
MAPK9 AHI1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK9 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK9 STIL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK9 LNX2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAPK9 CDC42 24234451 25241761 25348397 physical association physical interaction,proximity ligation assay ComPPI,IntAct
MAPK9 FOS 25348397 N/A physical interaction ComPPI
MAPK9 WNT7A 25348397 N/A physical interaction ComPPI
MAPK9 TAFA3 25348397 N/A physical interaction ComPPI
MAPK9 ZFC3H1 25348397 N/A physical interaction ComPPI
MAPK9 LRRC56 25348397 N/A physical interaction ComPPI
MAPK9 RHPN1 25348397 N/A physical interaction ComPPI
MAPK9 CCDC120 25348397 N/A physical interaction ComPPI
MAPK9 RASL10B 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 ZNF414 25348397 N/A physical interaction ComPPI
MAPK9 HOXC10 25348397 N/A physical interaction ComPPI
MAPK9 C5ORF24 25348397 N/A physical interaction ComPPI
MAPK9 TULP3 25348397 N/A physical interaction ComPPI
MAPK9 BCL2L1 25348397 N/A physical interaction ComPPI
MAPK9 TRIM25 25348397 N/A physical interaction ComPPI
MAPK9 PSEN1 25348397 N/A physical interaction ComPPI
MAPK9 NCSTN 25348397 N/A physical interaction ComPPI
MAPK9 STAT3 20871632 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
MAPK9 PIK3R1 24234451 25284480 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
MAPK9 ENKD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 ZNF559 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 ITGB3BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 MCRS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 CDC16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 C1ORF105 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 SAXO1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 ZNHIT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 PBX4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 SDCBP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 CBLL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 ZNF138 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 NHSL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 BNIP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 PICK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 PAX5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 GOLGA6A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 RSPO4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 REXO1L1P 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 MED12L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 LZTS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 IHO1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 KPNA3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 PPARG 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 GFAP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 GSC2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPK9 CTNNB1 18423204 19623618 19667122 27898060 stimulant N/A OmniPath
MAPK9 STMN1 20630875 27898060 inhibition N/A OmniPath
MAPK9 ARRB2 19060904 25416956 27898060 N/A N/A OmniPath
ARRB1 MAPK9 21988832 25416956 27898060 N/A N/A OmniPath
MAPK9 BAZ1B 19776015 27898060 stimulant N/A OmniPath
MAPK9 YAP1 17081983 18669648 21364637 27898060 N/A N/A OmniPath
DUSP4 MAPK9 25241761 27898060 8626452 inhibition N/A OmniPath
MAPK9 FOXO4 11313479 11689711 15538382 16272144 27898060 stimulant N/A OmniPath
MAPK9 BCL2L1 12633850 17369848 18794113 18974096 20363734 21840391 22617334 23953109 26188358 27898060 N/A N/A OmniPath
MAPK9 MYC 10551811 27898060 stimulant N/A OmniPath
MAPK9 BCL10 17189706 27898060 N/A N/A OmniPath
CASP3 MAPK9 12821118 27898060 N/A N/A OmniPath
MAPK9 APP 10341243 10936190 11146006 11517218 14970211 15178331 15944381 16223726 16554819 16705182 17085446 17459339 18833287 21947912 24610780 27898060 N/A N/A OmniPath
MAPK9 PPM1J 18553930 27898060 inhibition N/A OmniPath
MAPK9 IRS1 12417588 14579029 27898060 9335553 inhibition,stimulant N/A OmniPath
MAP2K4 MAPK9 11062067 1124203 12788955 14699111 17192257 17634293 18083107 18818208 19369195 19534553 20145118 21900206 22366412 22730327 27898060 9841871 stimulant N/A OmniPath
MAPK9 YWHAZ 15071501 27898060 inhibition N/A OmniPath
MAPK9 CDC25C 20220133 27898060 inhibition N/A OmniPath
MAPK9 STAT1 14963018 27898060 stimulant N/A OmniPath
MAPK9 ATF2 11865055 12110590 12788955 15192015 16533805 17875713 18669648 18767875 19413330 19651622 20068231 25416956 27898060 602896 7535770 7737129 7737130 8654373 stimulant N/A OmniPath
MAPK9 JUNB 27898060 8654373 8945519 9405416 inhibition N/A OmniPath
RAC1 MAPK9 18423204 27898060 stimulant N/A OmniPath
MAPK9 NR4A1 11274386 27898060 N/A N/A OmniPath
MAPK9 GORASP1 25948586 27898060 N/A N/A OmniPath
MAPK9 RARA 10383391 27898060 N/A N/A OmniPath
TP53 MAPK9 11283254 12384512 22366412 27898060 9393873 N/A N/A OmniPath
MAPK9 TP53 11283254 11896587 12384512 17525747 22366412 27898060 9393873 stimulant N/A OmniPath
MAPK9 MCL1 17670986 27898060 N/A N/A OmniPath
MAPK9 IRF3 19153595 27898060 N/A N/A OmniPath
MAPK9 RXRA 16551633 27898060 inhibition N/A OmniPath
MAPK9 BCL2L11 12591950 12818176 18691976 27898060 stimulant N/A OmniPath
MAPK9 GHR 27898060 8647880 9121492 N/A N/A OmniPath
DUSP1 MAPK9 11359773 27898060 8626452 inhibition N/A OmniPath
MAPK9 DUSP1 11359773 27898060 8626452 N/A N/A OmniPath
MAP2K6 MAPK9 27898060 8974401 stimulant N/A OmniPath
MAPK9 H2AX 18158901 27898060 stimulant N/A OmniPath
MAPK9 SFN 15071501 27898060 inhibition N/A OmniPath
MAPK9 MAPK8IP1 10490659 12756254 15911620 15998799 16195223 27898060 9733513 stimulant N/A OmniPath
MAPK8IP1 MAPK9 10490659 12756254 15998799 27898060 9733513 inhibition N/A OmniPath
IL1R1 MAPK9 27898060 9625767 stimulant N/A OmniPath
CSNK2A1 MAPK9 11062067 15755722 27898060 stimulant N/A OmniPath
MAPK9 PSEN1 18667537 27898060 stimulant N/A OmniPath
MAPK9 MAPT 12387894 15190058 15249677 16987243 17078951 18052981 18315566 19451179 19659459 20308788 20394726 20550628 21828286 24073234 25918155 27898060 9832145 N/A N/A OmniPath
MAPK9 SH3BP5 12167088 15158451 16964243 18669648 19413330 20068231 27898060 N/A N/A OmniPath
MAP2K7 MAPK9 11062067 11242024 12821118 16533805 17192257 19369195 27898060 9890973 stimulant N/A OmniPath
MAPK9 STAT3 18691976 20871632 27898060 stimulant N/A OmniPath
MAPK8 MAPK9 17525747 23602568 26186194 27898060 stimulant N/A OmniPath
MAPK9 MAPKAPK5 25241761 27898060 9628874 N/A N/A OmniPath
MAPK9 NBN 11252893 27898060 N/A N/A OmniPath
MAPK9 JUN 10490605 11278395 11948398 12040039 12788955 16533805 16824735 17189706 17875713 19118012 1922387 19527717 19910486 27898060 8001819 8654373 8945519 8985011 9405416 9925641 inhibition,stimulant N/A OmniPath
WDR62 MAPK9 16189514 19910486 25416956 27898060 N/A N/A OmniPath
MAPK9 WDR62 16189514 19910486 25416956 27898060 N/A N/A OmniPath
MAPK9 NFATC2 14517246 27898060 inhibition N/A OmniPath
MAPK9 JDP2 11602244 12225289 27898060 N/A N/A OmniPath
MAPK9 DUSP10 11359773 16288922 27898060 N/A N/A OmniPath
DUSP10 MAPK9 10597297 11359773 16288922 27898060 inhibition N/A OmniPath
MAPK9 NFATC4 17875713 27898060 inhibition N/A OmniPath
NFATC4 MAPK9 17875713 27898060 N/A N/A OmniPath
MAPK9 STAB2 18387958 27898060 N/A N/A OmniPath
MAPK9 MFN2 22748923 27898060 inhibition N/A OmniPath
MAPK9 DUSP16 11359773 14699111 27898060 N/A N/A OmniPath
DUSP16 MAPK9 11359773 11564882 14699111 27898060 inhibition N/A OmniPath
MAPK9 H3-3A 11278789 15994958 20068231 27898060 stimulant N/A OmniPath
MAPK9 MAP3K10 11278395 27898060 N/A N/A OmniPath
MAPK9 ELK1 17875713 27898060 8548291 8654373 8846788 9130707 stimulant N/A OmniPath
MAPK8IP2 MAPK9 10490659 1576768 27898060 stimulant N/A OmniPath
MAPK9 RARG 10383391 27898060 N/A N/A OmniPath
MAPK9 MAPK8IP3 10523642 10629060 11024282 12189133 15767678 27898060 stimulant N/A OmniPath
MAPK8IP3 MAPK9 10523642 10629060 11024282 12189133 15767678 27898060 stimulant N/A OmniPath
DUSP9 MAPK9 18296638 27898060 inhibition N/A OmniPath
DUSP19 MAPK9 11959861 27898060 N/A N/A OmniPath
MAPK9 MAPKAP1 15722200 27898060 N/A N/A OmniPath
NFE2 MAPK9 19966288 27898060 N/A N/A OmniPath
DUSP3 MAPK9 11971192 27898060 inhibition N/A OmniPath
MAPK9 GRIN2A 11675505 27898060 N/A N/A OmniPath
MAPK9 TOB1 12050114 12151396 27898060 inhibition N/A OmniPath
MAPK9 RRN3 15805466 27898060 inhibition,stimulant N/A OmniPath
MAPK9 ATN1 12812981 27898060 inhibition N/A OmniPath
MAPK9 NFATC3 14517246 27898060 9374467 9630228 inhibition,stimulant N/A OmniPath
DUSP14 MAPK9 11123293 27898060 inhibition N/A OmniPath
MAPK9 NES 12832492 27898060 N/A N/A OmniPath

Visualization










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