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GENE：MARCHF7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MARCHF7
FullNmae membrane associated ring-CH-type finger 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17393
EnsembleID ENSG00000136536
Uniprot Q9H992

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MARCHF7 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MARCHF7 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MARCHF7 GO:0002643,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005829,GO:0005886,GO:0006513,GO:0008270,GO:0008284,GO:0016740,GO:0031624,GO:0031624,GO:0042130,GO:0043130,GO:0043130,GO:0043518,GO:0050821,GO:0051865,GO:0051865,GO:0097371,GO:1901799,GO:1902166,GO:1902916,GO:1905524

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR MARCHF7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 MARCHF7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MARCHF7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000C5BAA MARCHF7 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MAPRE1 MARCHF7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D1 MARCHF7 25348397 N/A physical interaction ComPPI
EXOC8 MARCHF7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TGFBR2 MARCHF7 25348397 N/A physical interaction ComPPI
VAV2 MARCHF7 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RNF111 MARCHF7 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
USP7 MARCHF7 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBE2D2 MARCHF7 25348397 N/A physical interaction ComPPI
UBC MARCHF7 25348397 N/A physical interaction ComPPI
UBE2N MARCHF7 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAPT MARCHF7 25348397 N/A physical interaction ComPPI
MAPK6 MARCHF7 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
XPO1 MARCHF7 25348397 N/A physical interaction ComPPI
UBE2K MARCHF7 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2D3 MARCHF7 25348397 N/A physical interaction ComPPI
UBE2E1 MARCHF7 25348397 N/A physical interaction ComPPI
PPP3CA MARCHF7 25348397 N/A physical interaction ComPPI
PPP3CB MARCHF7 25348397 N/A physical interaction ComPPI
IQCB1 MARCHF7 25348397 N/A physical interaction ComPPI
UBE2M MARCHF7 25348397 N/A physical interaction ComPPI
NLRP3 MARCHF7 25348397 25594175 27898060 N/A physical interaction ComPPI,OmniPath
MAPRE3 MARCHF7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBXN1 MARCHF7 25348397 N/A physical interaction ComPPI
MARCHF7 USP9X 25348397 N/A physical interaction ComPPI
MARCHF7 TRIM65 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MARCHF7 TFDP3 25348397 N/A physical interaction ComPPI
MARCHF7 BBS7 25348397 N/A physical interaction ComPPI
MARCHF7 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
USP9X MARCHF7 18410486 27898060 stimulant N/A OmniPath
USP7 MARCHF7 16713569 18410486 23105109 27898060 stimulant N/A OmniPath

Visualization










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