Gene Information gene info

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GENE：MAZ

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MAZ
FullNmae MYC associated zinc finger protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6914
EnsembleID ENSG00000103495
Uniprot P56270

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MAZ apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MAZ apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MAZ GO:0000122,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0003723,GO:0005515,GO:0005634,GO:0006357,GO:0006367,GO:0006369,GO:0008284,GO:0010628,GO:0030335,GO:0045893,GO:0046872,GO:0051897,GO:2001234

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MAZ 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MAZ 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR MAZ 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000521626 MAZ 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS00003380CC MAZ 17612493 25416803 mrna cleavage,inhibition array technology TarBase
URS0000079D48 MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000070B1D MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 MAZ 19536157 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00000AA464 MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000A939F MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005CF5F MAZ 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001DA458 MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C3AC1 MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000060AABB MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000035AC91 MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 MAZ 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002C7B2B MAZ 23592263 25201524 25416803 26701625 28153728 mrna cleavage,inhibition experimental interaction detection,western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00001F5B39 MAZ 23592263 25416803 25487955 26701625 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay TarBase
URS00003758F0 MAZ 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000383DF4 MAZ 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001597DC MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F MAZ 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB MAZ 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B MAZ 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000ECE9C MAZ 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004505E4 MAZ 19536157 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001B968D MAZ 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002004E0 MAZ 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001919B0 MAZ 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 MAZ 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD MAZ 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A MAZ 19536157 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029D9F1 MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000031B6ED MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003E2232 MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001A6D0C MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004407DC MAZ 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 MAZ 22135298 phosphorylation N/A PhosphoSite
MAPK3 MAZ 22135298 phosphorylation N/A PhosphoSite
AKT1 MAZ 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
KEAP1 MAZ 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AIM2 MAZ 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
JUN MAZ 19028685 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK14 MAZ 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
GSK3B MAZ 24234451 25348397 29568061 association pull down ComPPI,IntAct
APOD MAZ 25348397 N/A physical interaction ComPPI
CSNK2A1 MAZ 10448092 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
EWSR1 MAZ 25348397 N/A physical interaction ComPPI
EEA1 MAZ 24234451 25348397 29568061 association pull down ComPPI,IntAct
CDK7 MAZ 24234451 25348397 29568061 association pull down ComPPI,IntAct
CDC14B MAZ 25348397 N/A physical interaction ComPPI
BPTF MAZ 10727212 14525934 15379550 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
MAZ DCC 11527412 12509857 14525934 24234451 25348397 27898060 physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
MAZ FOS 19028685 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MAZ HECW2 25348397 N/A physical interaction ComPPI
MAZ MOV10 25348397 N/A physical interaction ComPPI
MAZ NXF1 25348397 N/A physical interaction ComPPI
MAZ OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAZ PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MAZ KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
MAZ FBL 24234451 25348397 29568061 association pull down ComPPI,IntAct
NCBP3 MAZ 24234451 26382858 association pull down IntAct
MAPK3 MAZ 10448092 11809795 27898060 stimulant N/A OmniPath
CSNK2A1 MAZ 10448092 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009ADFC5 MAZ 27087310 direct interaction,inhibition N/A NPInter

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