GENE:MNT
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | MNT |
FullNmae | MAX network transcriptional repressor |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:7188 |
EnsembleID | ENSG00000070444 |
Uniprot | Q99583 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
MNT | mitotic_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MNT | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
MNT | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
MNT | GO:0000122,GO:0000122,GO:0000785,GO:0000977,GO:0000978,GO:0000981,GO:0000981,GO:0001227,GO:0001227,GO:0003682,GO:0003700,GO:0005515,GO:0005654,GO:0006357,GO:0006366,GO:0046983,GO:0051726,GO:0090398,GO:2001234 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | MNT | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ETS1 | MNT | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA2 | MNT | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXP3 | MNT | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
PRDM14 | MNT | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXP1 | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | MNT | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS000055128B | MNT | 19652553 | rna interference,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | miRSponge |
URS000055128B | MNT | 19652553 23618526 25416803 27418678 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,clip,miRNA interference luciferase reporter assay | TarBase |
URS00001597DC | MNT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00002075FA | MNT | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000393C7 | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000237E04 | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000B989F | MNT | 20371350 23313552 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001C770D | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000246356 | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003CC709 | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000BE495 | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000044FD7 | MNT | 20371350 23592263 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000E1E9E | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000032D69B | MNT | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001A7F58 | MNT | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000272A92 | MNT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DABC0 | MNT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000759B6A | MNT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003D4175 | MNT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000000EF0B | MNT | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EFBE3 | MNT | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001EB9FC | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS000014F13C | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002394F5 | MNT | 25416803 26701625 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000058863C | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS0000009265 | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00001919B0 | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002E728C | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00003AD2AA | MNT | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
URS00002373FD | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00002F72ED | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000BF7F9 | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000004BACE | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000055929F | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00005DEC41 | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00004929F1 | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000075D15B | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS00000EC1BE | MNT | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
URS000024CEE0 | MNT | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS00001CF056 | MNT | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
URS000020CEC2 | MNT | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
NCK2 | MNT | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SIN3A | MNT | 14525934 25348397 9184233 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
MYC | MNT | 25348397 | N/A | physical interaction | ComPPI |
HMGB1 | MNT | 11748221 14525934 25348397 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD |
SOX4 | MNT | 25348397 | N/A | physical interaction | ComPPI |
MXD1 | MNT | 25348397 | N/A | physical interaction | ComPPI |
ELAVL1 | MNT | 25348397 | N/A | physical interaction | ComPPI |
MLX | MNT | 10918583 11230181 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
MAD1L1 | MNT | 25348397 | N/A | physical interaction | ComPPI |
MNT | MAX | 14525934 24234451 25348397 25609649 27705803 9184233 | association | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,two hybrid | ComPPI,HPRD,IntAct |
MNT | HDAC1 | 25348397 | N/A | physical interaction | ComPPI |
MNT | CEBPA | 25348397 | N/A | physical interaction | ComPPI |
MNT | FOXK2 | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
MNT | UBE3A | 25348397 26506232 27898060 | N/A | physical interaction | ComPPI,OmniPath |
MNT | MXD3 | 25348397 | N/A | physical interaction | ComPPI |
MNT | MNT | 14525934 9184233 | N/A | experimental interaction detection,two hybrid | HPRD |
MNT | ITGB1 | 24234451 30021884 | physical association | cross-linking study | IntAct |
MNT | SMS | 24234451 30021884 | physical association | cross-linking study | IntAct |
MNT | TPR | 24234451 30021884 | physical association | cross-linking study | IntAct |
MAX | MNT | 18271930 20946988 25609649 27898060 7954804 9184233 | stimulant | N/A | OmniPath |