Gene Information gene info

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GENE：MSX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MSX1
FullNmae msh homeobox 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7391
EnsembleID ENSG00000163132
Uniprot P28360

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MSX1 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MSX1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MSX1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MSX1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
MSX1 GO:0000122,GO:0000785,GO:0000902,GO:0000976,GO:0000977,GO:0000981,GO:0000981,GO:0000987,GO:0001227,GO:0001228,GO:0001701,GO:0002039,GO:0003161,GO:0003198,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005667,GO:0006357,GO:0006366,GO:0007517,GO:0008285,GO:0009952,GO:0010463,GO:0023019,GO:0030308,GO:0030509,GO:0030513,GO:0030900,GO:0030901,GO:0034399,GO:0034504,GO:0035115,GO:0035116,GO:0035880,GO:0042474,GO:0042475,GO:0042482,GO:0043066,GO:0043517,GO:0043584,GO:0045944,GO:0048598,GO:0048839,GO:0048863,GO:0050821,GO:0051154,GO:0060021,GO:0060325,GO:0060349,GO:0060536,GO:0061180,GO:0061311,GO:0090427,GO:0097152,GO:1902255,GO:1990837,GO:2001055

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MSX1 hsa:4487 path:hsa05166 Human T-cell leukemia virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MSX1 TP53 15705871 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
PRDM14 MSX1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MSX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXE1 MSX1 21177256 trascriptional regulation,stimulation inferred by curator TFlink
PHOX2B MSX1 18201699 trascriptional regulation,stimulation inferred by curator TFlink
NFKB1 MSX1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005FDCD1 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001C85C7 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000044FD7 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004DEA91 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000156390 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001CC4BD MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075C4B1 MSX1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TP53 MSX1 25361965 interaction type N/A PTMCode2
MSX1 TP53 25361965 interaction type N/A PTMCode2
PAX9 MSX1 25361965 interaction type N/A PTMCode2
MSX1 PAX9 25361965 interaction type N/A PTMCode2
MSX1 SUMO1 25361965 interaction type N/A PTMCode2
SUMO1 MSX1 25361965 interaction type N/A PTMCode2
LHX2 MSX1 25361965 interaction type N/A PTMCode2
MSX1 LHX2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RBPMS MSX1 25348397 N/A two hybrid ComPPI
NMNAT1 MSX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TLE1 MSX1 14525934 16002402 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SP1 MSX1 10215616 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TBP MSX1 10215616 14525934 25348397 8700832 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TAF1 MSX1 14525934 25348397 8700832 N/A experimental interaction detection,in vivo ComPPI,HPRD
CREBBP MSX1 10215616 11115394 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
SUMO1 MSX1 14525934 16600910 16678795 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
PIAS1 MSX1 14525934 16600910 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RGS7 MSX1 10862767 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
SUMO2 MSX1 14525934 16600910 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TLE5 MSX1 14525934 16002402 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ING4 MSX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DLX5 MSX1 25348397 N/A physical interaction ComPPI
TLE2 MSX1 25348397 N/A physical interaction ComPPI
PAX3 MSX1 10529415 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
BCE1 MSX1 25348397 N/A in vitro ComPPI
MED19 MSX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MSX2 MSX1 14525934 25348397 9111364 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
POU2F1 MSX1 25348397 N/A in vitro ComPPI
MSX1 LHX2 14525934 25348397 27898060 9697309 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
MSX1 DLX2 25348397 N/A physical interaction ComPPI
MSX1 HOXC8 25348397 N/A physical interaction ComPPI
MSX1 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MSX1 TP53 14525934 15705871 N/A experimental interaction detection,two hybrid HPRD
PAX9 MSX1 14525934 16651263 27898060 N/A experimental interaction detection HPRD,OmniPath
MSX1 MSX1 14525934 16002402 N/A experimental interaction detection HPRD
MSX1 TP53 15705871 27898060 stimulant N/A OmniPath

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