Gene Information gene info

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GENE：NLE1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NLE1
FullNmae notchless homolog 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19889
EnsembleID ENSG00000073536
Uniprot Q9NVX2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NLE1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NLE1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NLE1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
NLE1 GO:0000027,GO:0000278,GO:0001756,GO:0001822,GO:0001826,GO:0005654,GO:0005730,GO:0005730,GO:0007219,GO:0045930,GO:0048705,GO:0061484,GO:0090263

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NLE1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF NLE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NLE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NLE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NLE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 NLE1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS0000122ED0 NLE1 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000324096 NLE1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00005651EE NLE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000153377 NLE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C4DB5 NLE1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F NLE1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 NLE1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075ABF4 NLE1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00002E728C NLE1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GTPBP4 NLE1 25361965 interaction type N/A PTMCode2
NLE1 GTPBP4 25361965 interaction type N/A PTMCode2
MRTO4 NLE1 25361965 interaction type N/A PTMCode2
NLE1 MRTO4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
THAP7 NLE1 25348397 N/A physical interaction ComPPI
NOL12 NLE1 25348397 N/A physical interaction ComPPI
NIFK NLE1 25348397 N/A physical interaction ComPPI
CYCS NLE1 25348397 N/A physical interaction ComPPI
JUN NLE1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RBM4 NLE1 25348397 N/A physical interaction ComPPI
CUL3 NLE1 25348397 N/A physical interaction ComPPI
EWSR1 NLE1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CCT5 NLE1 25348397 N/A physical interaction ComPPI
CCT7 NLE1 25348397 N/A physical interaction ComPPI
MTREX NLE1 25348397 N/A physical interaction ComPPI
MECP2 NLE1 25348397 N/A physical interaction ComPPI
TRIM25 NLE1 25348397 N/A physical interaction ComPPI
IGHMBP2 NLE1 25348397 N/A physical interaction ComPPI
IFI16 NLE1 25348397 N/A physical interaction ComPPI
RRP1B NLE1 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLEKHO1 NLE1 25348397 N/A physical interaction ComPPI
CHMP4B NLE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SPAG7 NLE1 25348397 N/A physical interaction ComPPI
WDR5 NLE1 25348397 N/A physical interaction ComPPI
HNRNPH3 NLE1 25348397 N/A physical interaction ComPPI
NLE1 SIRT7 25348397 N/A physical interaction ComPPI
NLE1 OBSL1 25348397 N/A physical interaction ComPPI
NLE1 NSA2 25348397 N/A physical interaction ComPPI
NLE1 GBE1 25348397 N/A physical interaction ComPPI
NLE1 MDN1 25348397 N/A physical interaction ComPPI
NLE1 NOP9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NLE1 CCT2 25348397 N/A physical interaction ComPPI
NLE1 CCT4 25348397 N/A physical interaction ComPPI
NLE1 CCT6A 25348397 N/A physical interaction ComPPI
NLE1 CNBP 25348397 N/A physical interaction ComPPI
NLE1 RPL18 25348397 N/A physical interaction ComPPI
NLE1 RPL15 25348397 N/A physical interaction ComPPI
NLE1 MACROH2A2 25348397 N/A physical interaction ComPPI
NLE1 RPL30 25348397 N/A physical interaction ComPPI
MTHFD1 NLE1 25348397 N/A physical interaction ComPPI
CHRM5 NLE1 24234451 28298427 physical association ubiquitin reconstruction IntAct

Visualization










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