Gene Information gene info

GENE:NOC2L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NOC2L
FullNmae NOC2 like nucleolar associated transcriptional repressor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24517
EnsembleID ENSG00000188976
Uniprot Q9Y3T9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NOC2L apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOC2L apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
NOC2L GO:0000122,GO:0000122,GO:0002903,GO:0003682,GO:0003714,GO:0003714,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005654,GO:0005694,GO:0005730,GO:0005730,GO:0005829,GO:0006915,GO:0030690,GO:0030691,GO:0031491,GO:0034644,GO:0042273,GO:0042393,GO:0042393,GO:0045815,GO:0140297,GO:2001243

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ATXN7 NOC2L 21078624 23180781 physical association pull down InnateDB
EED NOC2L 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NOC2L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 NOC2L 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF NOC2L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NOC2L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 NOC2L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 NOC2L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE NOC2L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D NOC2L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA NOC2L 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS00005ACA7C NOC2L 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237E04 NOC2L 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 NOC2L 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075D1FC NOC2L 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B0F8 NOC2L 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
DHX15 NOC2L 25348397 N/A physical interaction ComPPI
NPM1 NOC2L 25348397 N/A physical interaction ComPPI
FOXB1 NOC2L 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NIFK NOC2L 25348397 N/A physical interaction ComPPI
GLYR1 NOC2L 25348397 N/A physical interaction ComPPI
TBL3 NOC2L 25348397 N/A physical interaction ComPPI
RRS1 NOC2L 25348397 N/A physical interaction ComPPI
H4C1 NOC2L 25348397 N/A physical interaction ComPPI
FGF3 NOC2L 25348397 N/A physical interaction ComPPI
JUN NOC2L 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RPL18A NOC2L 25348397 N/A physical interaction ComPPI
CPNE2 NOC2L 25348397 N/A physical interaction ComPPI
NTRK1 NOC2L 25348397 N/A physical interaction ComPPI
JAK1 NOC2L 25348397 N/A physical interaction ComPPI
PDGFB NOC2L 25348397 N/A physical interaction ComPPI
ILK NOC2L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CA NOC2L 25348397 N/A physical interaction ComPPI
MYC NOC2L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPU NOC2L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GIPC1 NOC2L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
XPO1 NOC2L 25348397 N/A physical interaction ComPPI
H2AC18 NOC2L 25348397 N/A physical interaction ComPPI
AATF NOC2L 25348397 N/A physical interaction ComPPI
BRF2 NOC2L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS6 NOC2L 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MDM2 NOC2L 25348397 N/A physical interaction ComPPI
H3-4 NOC2L 25348397 N/A physical interaction ComPPI
H3C15 NOC2L 16322561 24234451 25348397 physical association pull down ComPPI,IntAct
RBFOX1 NOC2L 14525934 16713569 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RNF2 NOC2L 25348397 N/A physical interaction ComPPI
CEBPZ NOC2L 25348397 N/A physical interaction ComPPI
EED NOC2L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1AN NOC2L 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
MECP2 NOC2L 25348397 N/A physical interaction ComPPI
MAGED1 NOC2L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL7 NOC2L 25348397 N/A physical interaction ComPPI
H3C1 NOC2L 16322561 24234451 25348397 physical association pull down ComPPI,IntAct
EDA NOC2L 25348397 N/A physical interaction ComPPI
H3-3A NOC2L 16322561 24234451 25348397 physical association pull down ComPPI,IntAct
LRIF1 NOC2L 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NOP56 NOC2L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ILF2 NOC2L 25348397 N/A physical interaction ComPPI
DDX54 NOC2L 25348397 N/A physical interaction ComPPI
ATXN7 NOC2L 21078624 24234451 25348397 physical association two hybrid,pull down,physical interaction ComPPI,IntAct
AURKB NOC2L 25348397 N/A physical interaction ComPPI
IFI16 NOC2L 25348397 N/A physical interaction ComPPI
PES1 NOC2L 25348397 N/A physical interaction ComPPI
RRP1B NOC2L 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PLEKHO1 NOC2L 25348397 N/A physical interaction ComPPI
MPG NOC2L 25348397 N/A physical interaction ComPPI
SHMT2 NOC2L 25348397 N/A physical interaction ComPPI
SCN3B NOC2L 25348397 N/A physical interaction ComPPI
DDX56 NOC2L 25348397 N/A physical interaction ComPPI
RRP12 NOC2L 25348397 N/A physical interaction ComPPI
RPS14 NOC2L 25348397 N/A physical interaction ComPPI
DKC1 NOC2L 25348397 N/A physical interaction ComPPI
FTSJ3 NOC2L 25348397 N/A physical interaction ComPPI
MTF1 NOC2L 25348397 N/A physical interaction ComPPI
DDX24 NOC2L 25348397 N/A physical interaction ComPPI
NOC2L TP53 16322561 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification ComPPI,IntAct
NOC2L SIRT7 25348397 N/A physical interaction ComPPI
NOC2L ATN1 14525934 16713569 25348397 N/A physical interaction,two hybrid ComPPI,HPRD
NOC2L APP 25348397 N/A physical interaction ComPPI
NOC2L MOV10 25348397 N/A physical interaction ComPPI
NOC2L NXF1 25348397 N/A physical interaction ComPPI
NOC2L OBSL1 25348397 N/A physical interaction ComPPI
NOC2L CCDC8 25348397 N/A physical interaction ComPPI
NOC2L ZBTB38 25348397 N/A physical interaction ComPPI
NOC2L DDX52 25348397 N/A physical interaction ComPPI
NOC2L DDX18 25348397 N/A physical interaction ComPPI
NOC2L DDX31 25348397 N/A physical interaction ComPPI
NOC2L FBL 25348397 N/A physical interaction ComPPI
NOC2L GRWD1 25348397 N/A physical interaction ComPPI
NOC2L GTPBP4 25348397 N/A physical interaction ComPPI
NOC2L PUM3 25348397 N/A physical interaction ComPPI
NOC2L MRTO4 25348397 N/A physical interaction ComPPI
NOC2L NOP2 25348397 N/A physical interaction ComPPI
NOC2L NSA2 25348397 N/A physical interaction ComPPI
NOC2L RPL27 25348397 N/A physical interaction ComPPI
NOC2L WDR36 25348397 N/A physical interaction ComPPI
NOC2L NOL6 25348397 N/A physical interaction ComPPI
NOC2L RPF2 25348397 N/A physical interaction ComPPI
NOC2L SDAD1 25348397 N/A physical interaction ComPPI
NOC2L FOXL1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NOC2L FOXQ1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
NOC2L ZNF746 25348397 N/A physical interaction ComPPI
NOC2L MAK16 25348397 N/A physical interaction ComPPI
NOC2L RPL18 25348397 N/A physical interaction ComPPI
NOC2L MAGEB10 25348397 N/A physical interaction ComPPI
NOC2L FGF8 25348397 N/A physical interaction ComPPI
NOC2L RRP8 25348397 N/A physical interaction ComPPI
NOC2L RBM34 25348397 N/A physical interaction ComPPI
NOC2L ZNF512 25348397 N/A physical interaction ComPPI
NOC2L PHLDA3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NOC2L E2F3 22157815 24234451 25348397 association pull down ComPPI,IntAct
NOC2L MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
EBNA1BP2 NOC2L 25348397 N/A physical interaction ComPPI
PPIB NOC2L 24234451 30021884 physical association cross-linking study IntAct

Visualization