Gene Information gene info

GENE:NONO

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NONO
FullNmae non-POU domain containing octamer binding
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7871
EnsembleID ENSG00000147140
Uniprot Q15233

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NONO apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NONO apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
NONO GO:0001650,GO:0002218,GO:0003677,GO:0003682,GO:0003723,GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005694,GO:0006281,GO:0006310,GO:0006355,GO:0006397,GO:0007623,GO:0008380,GO:0016020,GO:0016363,GO:0016607,GO:0042382,GO:0042752,GO:0042802,GO:0045087,GO:0045892,GO:0090575,GO:0090650,GO:0106222,GO:1903377,GO:1904385

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTNNB1 NONO 16230076 23180781 physical association anti tag coimmunoprecipitation InnateDB
TOP1 NONO 17481653 23180781 physical association two hybrid InnateDB
EED NONO 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
NONO UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 NONO 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NONO 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NONO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NONO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NONO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NONO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NONO 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NONO 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000FC8EB NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017EA6A NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000137EDE NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000521626 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D NONO 22012620 23622248 25416803 mrna cleavage,inhibition clip,clash TarBase
URS00003BBF48 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA NONO 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000427B68 NONO 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000058DCD8 NONO 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004977C5 NONO 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5E03 NONO 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 NONO 22012620 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000259AE4 NONO 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000057A7C NONO 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F NONO 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 NONO 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000AD002 NONO 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 NONO 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C NONO 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NONO CRTC2 25361965 interaction type N/A PTMCode2
CRTC2 NONO 25361965 interaction type N/A PTMCode2
NONO SOCS3 25361965 interaction type N/A PTMCode2
SOCS3 NONO 25361965 interaction type N/A PTMCode2
NONO PSPC1 25361965 interaction type N/A PTMCode2
PSPC1 NONO 25361965 interaction type N/A PTMCode2
NONO SFPQ 25361965 interaction type N/A PTMCode2
SFPQ NONO 25361965 interaction type N/A PTMCode2
NONO SMARCA4 25361965 interaction type N/A PTMCode2
SMARCA4 NONO 25361965 interaction type N/A PTMCode2
NONO TOP1 25361965 interaction type N/A PTMCode2
TOP1 NONO 25361965 interaction type N/A PTMCode2
NONO AR 25361965 interaction type N/A PTMCode2
AR NONO 25361965 interaction type N/A PTMCode2
NONO RNF43 25361965 interaction type N/A PTMCode2
RNF43 NONO 25361965 interaction type N/A PTMCode2
SPI1 NONO 25361965 interaction type N/A PTMCode2
NONO SPI1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 NONO 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
LMO4 NONO 25348397 N/A physical interaction ComPPI
DDX6 NONO 25348397 N/A physical interaction ComPPI
UBE2I NONO 25348397 N/A physical interaction ComPPI
SNW1 NONO 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC5L NONO 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SNRPA NONO 25348397 N/A physical interaction ComPPI
SOCS3 NONO 25348397 N/A physical interaction ComPPI
PLEKHF2 NONO 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRKAA2 NONO 25348397 N/A physical interaction ComPPI
BHLHE40 NONO 23555304 24234451 25348397 physical association two hybrid ComPPI,IntAct
FXR2 NONO 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CD2BP2 NONO 25348397 N/A physical interaction ComPPI
PPP1CC NONO 25348397 N/A physical interaction ComPPI
SMARCC1 NONO 25348397 N/A physical interaction ComPPI
TP53BP1 NONO 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
LMNA NONO 25348397 N/A physical interaction ComPPI
PPP1CB NONO 25348397 N/A physical interaction ComPPI
CCDC22 NONO 25348397 N/A physical interaction ComPPI
KEAP1 NONO 25348397 N/A physical interaction ComPPI
COX5A NONO 25348397 N/A physical interaction ComPPI
SMN1 NONO 19928837 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CD81 NONO 25348397 N/A physical interaction ComPPI
FBXW7 NONO 25348397 N/A physical interaction ComPPI
SPI1 NONO 14525934 25348397 27898060 8626664 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
GRB2 NONO 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN NONO 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
AR NONO 12810069 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SMARCD1 NONO 25348397 N/A physical interaction ComPPI
COPS5 NONO 25348397 N/A physical interaction ComPPI
HDAC3 NONO 25348397 N/A physical interaction ComPPI
TPM2 NONO 25348397 N/A physical interaction ComPPI
NONO CA2 10821857 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
NONO SFPQ 12403470 14525934 21988832 24234451 25348397 30021884 physical association two hybrid,cross-linking study,experimental interaction detection,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
NONO POLR2A 12358429 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
NONO MAD1L1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NONO POLR1H 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NONO PSPC1 16148043 16169070 22416126 24234451 25348397 25416956 27898060 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct,OmniPath
NONO PMS1 25348397 N/A physical interaction ComPPI
NONO PITX3 25348397 N/A physical interaction ComPPI
NONO SRRM2 25348397 N/A physical interaction ComPPI
NONO SMARCA2 25348397 N/A physical interaction ComPPI
NONO SMARCA4 25348397 N/A physical interaction ComPPI
NONO SMARCB1 25348397 N/A physical interaction ComPPI
NONO HDAC1 25348397 N/A physical interaction ComPPI
NONO TOPORS 25348397 N/A physical interaction ComPPI
NONO TADA2A 25348397 N/A physical interaction ComPPI
NONO H2AX 20000738 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NONO MYC 17314511 21150319 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
NONO HDAC5 25348397 N/A physical interaction ComPPI
NONO TOP1 15848144 24234451 25348397 association anti bait coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
NONO PSMA3 25348397 N/A physical interaction ComPPI
NONO PPP1CA 25348397 N/A physical interaction ComPPI
NONO SIN3A 25348397 N/A physical interaction ComPPI
NONO U2AF2 25348397 N/A physical interaction ComPPI
NONO SMARCAD1 25348397 N/A physical interaction ComPPI
NONO PARK7 25348397 N/A physical interaction ComPPI
NONO HDAC2 25348397 N/A physical interaction ComPPI
NONO ELAVL1 25348397 N/A physical interaction ComPPI
NONO ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NONO HNRNPA1 22446626 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
NONO TSG101 25348397 N/A physical interaction ComPPI
NONO NR2C1 25348397 N/A physical interaction ComPPI
NONO CUL3 25348397 N/A physical interaction ComPPI
NONO CUL2 25348397 N/A physical interaction ComPPI
NONO CAND1 25348397 N/A physical interaction ComPPI
NONO KCND3 25348397 N/A physical interaction ComPPI
NONO EPS15 25348397 N/A physical interaction ComPPI
NONO HNRNPM 25348397 N/A physical interaction ComPPI
NONO HNRNPU 25348397 N/A physical interaction ComPPI
NONO CPSF6 25348397 N/A physical interaction ComPPI
NONO FUS 25348397 N/A physical interaction ComPPI
NONO SCO2 25348397 N/A physical interaction ComPPI
NONO AGMAT 25348397 N/A physical interaction ComPPI
NONO SCARB2 25348397 N/A physical interaction ComPPI
NONO SON 25348397 N/A physical interaction ComPPI
NONO STRN4 25348397 N/A physical interaction ComPPI
NONO TMED9 25348397 N/A physical interaction ComPPI
NONO SLK 25348397 N/A physical interaction ComPPI
NONO RALB 25348397 N/A physical interaction ComPPI
NONO GORASP2 25348397 N/A physical interaction ComPPI
NONO TRIM24 25348397 N/A physical interaction ComPPI
NONO MRPL39 25348397 N/A physical interaction ComPPI
NONO NUP133 25348397 N/A physical interaction ComPPI
NONO POP1 25348397 N/A physical interaction ComPPI
NONO SQOR 25348397 N/A physical interaction ComPPI
NONO RALA 25348397 N/A physical interaction ComPPI
NONO ZC3H11A 25348397 N/A physical interaction ComPPI
NONO MRPL41 25348397 N/A physical interaction ComPPI
NONO RRM2 25348397 N/A physical interaction ComPPI
NONO ATP6V0A1 25348397 N/A physical interaction ComPPI
NONO SUGP2 25348397 N/A physical interaction ComPPI
NONO DLD 25348397 N/A physical interaction ComPPI
NONO RPL36 25348397 N/A physical interaction ComPPI
NONO UBAC2 25348397 N/A physical interaction ComPPI
NONO CTTN 25348397 N/A physical interaction ComPPI
NONO HSPA1A 25348397 N/A physical interaction ComPPI
NONO HSPA1B 25348397 N/A physical interaction ComPPI
NONO FN1 25348397 N/A physical interaction ComPPI
NONO VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
NONO RNF43 18655028 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct
NONO TP63 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
NONO IL7R 25348397 N/A physical interaction ComPPI
NONO ITGA4 25348397 N/A physical interaction ComPPI
NONO CTNNB1 25348397 N/A physical interaction ComPPI
NONO PAN2 25348397 N/A physical interaction ComPPI
NONO EWSR1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NONO ORC5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NONO IRAK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NONO SYNPO 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NONO YLPM1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NONO TCERG1 25348397 N/A physical interaction ComPPI
NONO WBP4 25348397 N/A physical interaction ComPPI
NONO APBB1 25348397 N/A physical interaction ComPPI
NONO RPA2 25348397 N/A physical interaction ComPPI
NONO RPA3 25348397 N/A physical interaction ComPPI
NONO WWOX 25348397 N/A physical interaction ComPPI
NONO ERG 25348397 N/A physical interaction ComPPI
NONO ASB3 25348397 N/A physical interaction ComPPI
NONO STAU1 25348397 N/A physical interaction ComPPI
NONO PTBP1 25348397 N/A physical interaction ComPPI
NONO HUWE1 25348397 N/A physical interaction ComPPI
NONO C11ORF68 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NONO NUPR1 16478804 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
NONO H3-4 25348397 N/A physical interaction ComPPI
NONO CUL7 25348397 N/A physical interaction ComPPI
NONO OBSL1 25348397 N/A physical interaction ComPPI
NONO CCDC8 25348397 N/A physical interaction ComPPI
NONO EED 25348397 N/A physical interaction ComPPI
NONO ESR1 24234451 25348397 25604459 association physical interaction,tandem affinity purification ComPPI,IntAct
NONO BHLHE41 25348397 N/A physical interaction ComPPI
NONO DELEC1 25348397 N/A physical interaction ComPPI
NONO RPS6KB2 25348397 N/A physical interaction ComPPI
NONO DYNC2H1 25348397 N/A physical interaction ComPPI
NONO HABP4 25348397 N/A physical interaction ComPPI
NONO HNRNPA3 25348397 N/A physical interaction ComPPI
NONO IBA57 25348397 N/A physical interaction ComPPI
NONO NDUFS3 25348397 N/A physical interaction ComPPI
NONO ZFAND6 25348397 N/A physical interaction ComPPI
NONO NUP210 25348397 N/A physical interaction ComPPI
NONO SFN 25348397 N/A physical interaction ComPPI
NONO NTRK1 25348397 N/A physical interaction ComPPI
NONO XPO1 25348397 N/A physical interaction ComPPI
NONO CRY2 25348397 N/A physical interaction ComPPI
NONO RC3H1 25348397 N/A physical interaction ComPPI
NONO UBR5 25348397 N/A physical interaction ComPPI
NONO ZNF746 25348397 N/A physical interaction ComPPI
NONO TET2 25348397 N/A physical interaction ComPPI
NONO PROSER1 25348397 N/A physical interaction ComPPI
NONO GYG2 25348397 N/A physical interaction ComPPI
NONO SERPINB7 25348397 N/A physical interaction ComPPI
NONO SERPINB8 25348397 N/A physical interaction ComPPI
NONO SERPINA12 25348397 N/A physical interaction ComPPI
NONO ASAH1 25348397 N/A physical interaction ComPPI
NONO CTSH 25348397 N/A physical interaction ComPPI
NONO TGM1 25348397 N/A physical interaction ComPPI
NONO CST6 25348397 N/A physical interaction ComPPI
NONO CYLD 25348397 N/A physical interaction ComPPI
NONO ECD 25348397 N/A physical interaction ComPPI
NONO TRIM25 25348397 N/A physical interaction ComPPI
NONO UBE2A 25348397 N/A physical interaction ComPPI
NONO HEY1 25348397 N/A physical interaction ComPPI
NONO MTF1 25348397 N/A physical interaction ComPPI
NONO HDAC6 25348397 N/A physical interaction ComPPI
NONO MYCN 25348397 N/A physical interaction ComPPI
NONO CRTC2 18077367 24234451 25348397 27898060 physical association anti bait coimmunoprecipitation,fluorescent resonance energy transfer,physical interaction ComPPI,IntAct,OmniPath
NONO RELB 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NONO RIPK3 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NONO TBK1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NONO TRAF1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
NONO MED19 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO MED9 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO MED29 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO MAPK13 19135240 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO MLH1 20706999 24234451 25348397 physical association two hybrid ComPPI,IntAct
NONO MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO YBX1 22118625 24234451 25348397 association tandem affinity purification ComPPI,IntAct
NONO CHEK2 23178491 24234451 25348397 association tandem affinity purification ComPPI,IntAct
NONO DUX4 24234451 25348397 26816005 association pull down ComPPI,IntAct
NONO AURKA 24234451 24358021 25348397 physical association molecular sieving ComPPI,IntAct
NONO ANG 24234451 25348397 28777577 association anti bait coimmunoprecipitation ComPPI,IntAct
NONO OCRL 24234451 25107275 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO JMJD6 24234451 24498420 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
PRPF40A NONO 25348397 N/A physical interaction ComPPI
RPA1 NONO 25348397 N/A physical interaction ComPPI
CHAF1A NONO 25348397 N/A physical interaction ComPPI
CSTF2 NONO 25348397 N/A physical interaction ComPPI
SRRM1 NONO 25348397 N/A physical interaction ComPPI
DDX41 NONO 24234451 25348397 25920683 association anti tag coimmunoprecipitation ComPPI,IntAct
ALDH18A1 NONO 25348397 N/A physical interaction ComPPI
NONO NONO 14525934 16148043 16189514 21988832 22416126 23555304 24234451 physical association anti tag coimmunoprecipitation,two hybrid,two hybrid pooling approach,two hybrid HPRD,IntAct
METTL3 NONO 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 NONO 24234451 29507755 association anti tag coimmunoprecipitation IntAct
NONO GALNT5 24234451 30021884 physical association cross-linking study IntAct
NONO HEATR3 24234451 30021884 physical association cross-linking study IntAct
NONO AKAP9 24234451 30021884 physical association cross-linking study IntAct
HNRNPDL NONO 24234451 30021884 physical association cross-linking study IntAct
NONO STK10 24234451 30021884 physical association cross-linking study IntAct
NONO LIX1L 24234451 30021884 physical association cross-linking study IntAct
NONO GOLGA8DP 24234451 30021884 physical association cross-linking study IntAct
NONO DHX57 24234451 30021884 physical association cross-linking study IntAct
NONO MYO5C 24234451 30021884 physical association cross-linking study IntAct
MATR3 NONO 11525732 27898060 N/A N/A OmniPath
SFPQ NONO 10858305 12403470 17145710 17452459 17507659 18042045 20421735 21988832 22939629 26344197 27898060 stimulant N/A OmniPath
NONO TOP1 10858305 17481653 27898060 9756848 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008B4C4E NONO 27087310 direct interaction,inhibition N/A NPInter

Visualization