Gene Information gene info

GENE:NOX1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NOX1
FullNmae NADPH oxidase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7889
EnsembleID ENSG00000007952
Uniprot Q9Y5S8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NOX1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOX1 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
NOX1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NOX1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
NOX1 GO:0001525,GO:0003081,GO:0005244,GO:0005515,GO:0005769,GO:0005886,GO:0005886,GO:0006739,GO:0006952,GO:0006954,GO:0007165,GO:0007254,GO:0008217,GO:0008284,GO:0008631,GO:0010575,GO:0016175,GO:0016175,GO:0016175,GO:0016175,GO:0016477,GO:0030198,GO:0031267,GO:0034220,GO:0034765,GO:0042554,GO:0042554,GO:0042554,GO:0042743,GO:0042995,GO:0043020,GO:0043020,GO:0045726,GO:0045730,GO:0046330,GO:0046872,GO:0048661,GO:0050661,GO:0051454,GO:0070161,GO:0071455,GO:0072592,GO:1902177,GO:1990451

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NOX1 hsa:27035 path:hsa04380 Osteoclast differentiation - Homo sapiens (human)
NOX1 hsa:27035 path:hsa04933 AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human)
NOX1 hsa:27035 path:hsa05010 Alzheimer disease - Homo sapiens (human)
NOX1 hsa:27035 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
NOX1 hsa:27035 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
NOX1 hsa:27035 path:hsa05417 Lipid and atherosclerosis - Homo sapiens (human)
NOX1 hsa:27035 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
NOX1 NOXA1 20110267 23180781 physical association affinity chromatography technology InnateDB
RELA NOX1 20457132 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CEBPA NOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 NOX1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIPK2 NOX1 20171273 trascriptional regulation,stimulation inferred by curator TFlink
STAT1 NOX1 19834108 trascriptional regulation,stimulation inferred by curator TFlink
STAT3 NOX1 19834108 trascriptional regulation,stimulation inferred by curator TFlink
STAT4 NOX1 19834108 trascriptional regulation,stimulation inferred by curator TFlink
AR NOX1 N/A trascriptional regulation,stimulation inferred by curator TFlink
PPARA NOX1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CYBA NOX1 25361965 interaction type N/A PTMCode2
NOX1 CYBA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TNFRSF1A NOX1 19641494 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CYBA NOX1 14525934 15322091 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PPP2R3B NOX1 25348397 N/A physical interaction ComPPI
NOXA1 NOX1 25348397 N/A physical interaction ComPPI
NOX1 RHBDD1 25348397 N/A physical interaction ComPPI
SRC NOX1 15774483 27898060 N/A N/A OmniPath
NOX1 TXN 20347035 27898060 N/A N/A OmniPath
NOX1 NFE2L2 18802114 20347035 27898060 N/A N/A OmniPath

Visualization