GENE:NOX1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | NOX1 |
FullNmae | NADPH oxidase 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:7889 |
EnsembleID | ENSG00000007952 |
Uniprot | Q9Y5S8 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
NOX1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
NOX1 | ferroptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
NOX1 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
NOX1 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
NOX1 | GO:0001525,GO:0003081,GO:0005244,GO:0005515,GO:0005769,GO:0005886,GO:0005886,GO:0006739,GO:0006952,GO:0006954,GO:0007165,GO:0007254,GO:0008217,GO:0008284,GO:0008631,GO:0010575,GO:0016175,GO:0016175,GO:0016175,GO:0016175,GO:0016477,GO:0030198,GO:0031267,GO:0034220,GO:0034765,GO:0042554,GO:0042554,GO:0042554,GO:0042743,GO:0042995,GO:0043020,GO:0043020,GO:0045726,GO:0045730,GO:0046330,GO:0046872,GO:0048661,GO:0050661,GO:0051454,GO:0070161,GO:0071455,GO:0072592,GO:1902177,GO:1990451 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
NOX1 | hsa:27035 | path:hsa04380 | Osteoclast differentiation - Homo sapiens (human) |
NOX1 | hsa:27035 | path:hsa04933 | AGE-RAGE signaling pathway in diabetic complications - Homo sapiens (human) |
NOX1 | hsa:27035 | path:hsa05010 | Alzheimer disease - Homo sapiens (human) |
NOX1 | hsa:27035 | path:hsa05022 | Pathways of neurodegeneration - multiple diseases - Homo sapiens (human) |
NOX1 | hsa:27035 | path:hsa05208 | Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human) |
NOX1 | hsa:27035 | path:hsa05417 | Lipid and atherosclerosis - Homo sapiens (human) |
NOX1 | hsa:27035 | path:hsa05418 | Fluid shear stress and atherosclerosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
CEBPA | NOX1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | NOX1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HIPK2 | NOX1 | 20171273 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT1 | NOX1 | 19834108 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT3 | NOX1 | 19834108 | trascriptional regulation,stimulation | inferred by curator | TFlink |
STAT4 | NOX1 | 19834108 | trascriptional regulation,stimulation | inferred by curator | TFlink |
AR | NOX1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
PPARA | NOX1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TNFRSF1A | NOX1 | 19641494 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CYBA | NOX1 | 14525934 15322091 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
PPP2R3B | NOX1 | 25348397 | N/A | physical interaction | ComPPI |
NOXA1 | NOX1 | 25348397 | N/A | physical interaction | ComPPI |
NOX1 | RHBDD1 | 25348397 | N/A | physical interaction | ComPPI |
SRC | NOX1 | 15774483 27898060 | N/A | N/A | OmniPath |
NOX1 | TXN | 20347035 27898060 | N/A | N/A | OmniPath |
NOX1 | NFE2L2 | 18802114 20347035 27898060 | N/A | N/A | OmniPath |