Gene Information gene info

GENE:PAK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PAK2
FullNmae p21 (RAC1) activated kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8591
EnsembleID ENSG00000180370
Uniprot Q13177

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PAK2 necroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAK2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAK2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAK2 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAK2 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PAK2 GO:0002223,GO:0003300,GO:0004672,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0004674,GO:0005515,GO:0005524,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0005911,GO:0006468,GO:0006468,GO:0006469,GO:0006915,GO:0007165,GO:0014069,GO:0016310,GO:0018105,GO:0019901,GO:0030141,GO:0030296,GO:0031267,GO:0034333,GO:0035556,GO:0042802,GO:0043066,GO:0043066,GO:0043408,GO:0045296,GO:0046777,GO:0048010,GO:0048471,GO:0050731,GO:0050770,GO:0051179,GO:0051493,GO:0051497,GO:0060996,GO:0070830,GO:0071407,GO:0071560,GO:0098978,GO:0106310,GO:0150105,GO:2001238,GO:2001271

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PAK2 hsa:5062 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
PAK2 hsa:5062 path:hsa04012 ErbB signaling pathway - Homo sapiens (human)
PAK2 hsa:5062 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
PAK2 hsa:5062 path:hsa04360 Axon guidance - Homo sapiens (human)
PAK2 hsa:5062 path:hsa04510 Focal adhesion - Homo sapiens (human)
PAK2 hsa:5062 path:hsa04660 T cell receptor signaling pathway - Homo sapiens (human)
PAK2 hsa:5062 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
PAK2 hsa:5062 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
PAK2 hsa:5062 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
PAK2 hsa:5062 path:hsa05211 Renal cell carcinoma - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CASP3 PAK2 23180781 9171063 cleavage reaction protease assay InnateDB
PAK2 PAK2 12453877 15908432 23180781 phosphorylation reaction protein kinase assay InnateDB
HSPA5 PAK2 15908432 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCK1 PAK2 11278553 23180781 physical association anti tag coimmunoprecipitation InnateDB
PAK2 SYK 14673144 23180781 physical association anti tag coimmunoprecipitation InnateDB
PAK2 ARHGEF6 17392278 23180781 phosphorylation reaction protein kinase assay InnateDB
MYLK PAK2 10748018 23180781 phosphorylation reaction protein kinase assay InnateDB
PRL PAK2 11943200 23180781 phosphorylation reaction protein kinase assay InnateDB
MYC PAK2 14749374 23180781 phosphorylation reaction anti tag coimmunoprecipitation InnateDB
NF2 PAK2 11719502 23180781 phosphorylation reaction protein kinase assay InnateDB
CTTN PAK2 12453877 23180781 phosphorylation reaction protein kinase assay InnateDB
GZMM PAK2 19103589 23180781 protein cleavage protease assay InnateDB
RAC1 PAK2 23331499 9823899 stimulation N/A SignaLink,SignaLink
CDC42 PAK2 10320322 23331499 9823899 stimulation N/A SignaLink
PAK2 RAF1 10712905 16837009 23331499 stimulation N/A SignaLink
PAK2 MAP2K3 23331499 7499279 stimulation N/A SignaLink
PAK2 ABL1 11121037 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ABI1 PAK2 20005715 interaction type N/A PSP
GRB2 PAK2 20005715 interaction type N/A PSP
NCK1 PAK2 20005715 interaction type N/A PSP
NPHP1 PAK2 20005715 interaction type N/A PSP
PPP2R2B PAK2 20005715 interaction type N/A PSP,SignaLink
RPS6 PAK2 20005715 interaction type N/A PSP
SH3GL2 PAK2 20005715 interaction type N/A PSP
SORBS1 PAK2 20005715 interaction type N/A PSP
SORBS3 PAK2 20005715 interaction type N/A PSP
ABI1 PAK2 20005715 N/A N/A SignaLink
GRB2 PAK2 20005715 N/A N/A SignaLink
NCK1 PAK2 20005715 20005715 N/A N/A SignaLink
NPHP1 PAK2 20005715 20005715 N/A N/A SignaLink
RPS6 PAK2 20005715 20005715 N/A N/A SignaLink
SH3GL2 PAK2 20005715 20005715 N/A N/A SignaLink
SORBS1 PAK2 20005715 20005715 N/A N/A SignaLink
SORBS3 PAK2 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR PAK2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 PAK2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 PAK2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 PAK2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PAK2 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 PAK2 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C PAK2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PAK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PAK2 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 PAK2 20584899 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS000039A052 PAK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 PAK2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000004203C PAK2 22012620 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 PAK2 22989374 25416803 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr TarBase
URS0000527B00 PAK2 20371350 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002A71AD PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000001A7A PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 PAK2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001A6D0C PAK2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004C5774 PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000292B1 PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000005D4F5 PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCDA3 PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000048F59D PAK2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 PAK2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F PAK2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A92 PAK2 25416803 26363097 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00001E3523 PAK2 25416803 26186482 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS000075AB0E PAK2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000016FF9C PAK2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PRKAA2 PAK2 22135298 phosphorylation N/A PhosphoSite
PAK2 PAK2 22135298 phosphorylation N/A PhosphoSite
PAK2 JUN 22135298 phosphorylation N/A PhosphoSite
PAK2 H4C1 22135298 phosphorylation N/A PhosphoSite
PAK2 PXN 22135298 phosphorylation N/A PhosphoSite
PAK2 CALD1 22135298 phosphorylation N/A PhosphoSite
PAK2 CASP7 22135298 phosphorylation N/A PhosphoSite
PAK2 MAPK6 22135298 phosphorylation N/A PhosphoSite
PAK2 ABL1 22135298 phosphorylation N/A PhosphoSite
PAK2 NF2 22135298 phosphorylation N/A PhosphoSite
PAK2 SMAD2 22135298 phosphorylation N/A PhosphoSite
PAK2 EIF4G1 22135298 phosphorylation N/A PhosphoSite
PAK2 PREX2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
PIN1 PAK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NCK2 PAK2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YES1 PAK2 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
PLAA PAK2 25348397 N/A physical interaction ComPPI
CDC42 PAK2 10320322 14525934 16204230 17353931 20936779 24234451 25348397 25416956 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,two hybrid array,two hybrid pooling approach,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
SH3KBP1 PAK2 12829691 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PACSIN3 PAK2 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SORBS3 PAK2 14525934 16374509 21516116 24234451 25348397 25416956 physical association two hybrid,experimental interaction detection,filter binding,phage display,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
PAK2 RPS6 14525934 1985906 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 SRC 12215529 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,physical interaction,in vitro ComPPI,HPRD,IntAct
PAK2 VIM 11895474 14525934 2500966 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 SYN1 10571231 12237306 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PAK2 NCK1 11160719 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,in vitro,in vivo ComPPI,HPRD,IntAct
PAK2 CASP3 14525934 16204230 24234451 25241761 25348397 9786869 physical association experimental interaction detection,physical interaction,in vitro,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
PAK2 MYLK 10748018 14525934 2160950 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PAK2 RAC1 14525934 19264842 20696164 20936779 22705156 24234451 25348397 9535855 physical association experimental interaction detection,pull down,physical interaction,two hybrid pooling approach,in vitro,solid phase assay ComPPI,HPRD,IntAct
PAK2 ABI1 11956071 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 ARHGEF7 12226077 14525934 16374509 16787945 24234451 25348397 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,filter binding,phage display,physical interaction,competition binding,in vitro,in vivo ComPPI,HPRD,IntAct
PAK2 ABI3 11956071 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PAK2 MAPK1 14525934 15031289 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 MAPK3 12226077 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PAK2 ARHGAP10 14525934 15471851 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PAK2 LCK 14525934 16374509 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PAK2 HCK 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,physical interaction,in vitro ComPPI,HPRD,IntAct
PAK2 LYN 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
PAK2 FYN 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
PAK2 SNX9 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 SNX33 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 NPHP1 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 SH3PXD2A 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
PAK2 SH3GL2 14525934 16374509 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PAK2 GRB2 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,in vitro ComPPI,HPRD,IntAct
PAK2 ARHGEF6 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct
PAK2 SORBS2 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,in vitro ComPPI,HPRD,IntAct
PAK2 SORBS1 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,in vitro ComPPI,HPRD,IntAct
PAK2 SH3RF3 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,phage display,physical interaction,in vitro ComPPI,HPRD,IntAct
PAK2 SH3RF1 14525934 16374509 24234451 25348397 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
PAK2 LIMK1 14525934 16837009 24234451 25348397 phosphorylation reaction experimental interaction detection,nuclear magnetic resonance,protein kinase assay,in vitro ComPPI,HPRD,IntAct
PAK2 RAF1 14525934 16837009 24234451 25348397 phosphorylation reaction experimental interaction detection,nuclear magnetic resonance,protein kinase assay,in vitro ComPPI,HPRD,IntAct
PAK2 EIF4G1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,in vivo ComPPI,IntAct
PAK2 EIF4B 14525934 16281055 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
PAK2 MYL2 10047984 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PAK2 GIT1 16787945 17353931 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 GIT2 17353931 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 MYH10 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 MCM3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 DOCK2 25348397 N/A physical interaction ComPPI
PAK2 RAC2 25348397 N/A physical interaction ComPPI
PAK2 ABL1 11121037 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
PAK2 DST 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAK2 EP300 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAK2 BRAF 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PAK2 ELAVL1 25348397 N/A physical interaction ComPPI
PAK2 H4C1 25348397 N/A physical interaction ComPPI
PAK2 APP 25348397 N/A physical interaction ComPPI
PAK2 MYC 25348397 N/A physical interaction ComPPI
PAK2 HSPA5 25348397 N/A physical interaction ComPPI
PAK2 RIOK3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PAK2 G6PD 25348397 N/A physical interaction ComPPI
PAK2 NPEPPS 25348397 N/A physical interaction ComPPI
PAK2 CAPNS1 25348397 N/A physical interaction ComPPI
PAK2 CKB 25348397 N/A physical interaction ComPPI
PAK2 EEF2 25348397 N/A physical interaction ComPPI
PAK2 ERP44 25348397 N/A physical interaction ComPPI
PAK2 ISOC1 25348397 N/A physical interaction ComPPI
PAK2 LDHB 25348397 N/A physical interaction ComPPI
PAK2 PAFAH1B1 25348397 N/A physical interaction ComPPI
PAK2 SCLY 25348397 N/A physical interaction ComPPI
PAK2 YWHAB 25348397 N/A physical interaction ComPPI
PAK2 YWHAH 25348397 N/A physical interaction ComPPI
PAK2 YWHAZ 25348397 N/A physical interaction ComPPI
PAK2 PFAS 25348397 N/A physical interaction ComPPI
PAK2 SFN 25348397 N/A physical interaction ComPPI
PAK2 TGM2 25348397 N/A physical interaction ComPPI
PAK2 UBE2R2 25348397 N/A physical interaction ComPPI
PAK2 UBFD1 25348397 N/A physical interaction ComPPI
PAK2 YWHAE 25348397 N/A physical interaction ComPPI
PAK2 YWHAG 25348397 N/A physical interaction ComPPI
PAK2 ZFYVE19 25348397 N/A physical interaction ComPPI
PAK2 PAK1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PAK2 RHOJ 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PAK2 FSD1 25348397 N/A physical interaction ComPPI
PAK2 OR10H3 25348397 N/A physical interaction ComPPI
PAK2 SOX2 25348397 N/A physical interaction ComPPI
PAK2 PLK2 25348397 N/A physical interaction ComPPI
PAK2 GDI1 25348397 N/A physical interaction ComPPI
PAK2 MYO6 25348397 N/A physical interaction ComPPI
PAK2 ILKAP 25348397 N/A physical interaction ComPPI
PAK2 PSME1 25348397 N/A physical interaction ComPPI
PAK2 THOC3 25348397 N/A physical interaction ComPPI
PAK2 PDIA3 25348397 N/A physical interaction ComPPI
PAK2 STAT1 25348397 N/A physical interaction ComPPI
PAK2 NTRK1 25348397 N/A physical interaction ComPPI
PAK2 SCLT1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PAK2 CDKN2AIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 SKP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 FBXO28 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAK2 MKNK1 14525934 15234964 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,proximity ligation assay ComPPI,HPRD,IntAct
PAK2 CDH1 25348397 N/A physical interaction ComPPI
PAK2 SNRNP27 25348397 N/A physical interaction ComPPI
PAK2 OCRL 25348397 N/A physical interaction ComPPI
PAK2 ICAM1 25348397 N/A physical interaction ComPPI
PAK2 FGB 25348397 N/A physical interaction ComPPI
PAK2 KIFAP3 25348397 N/A physical interaction ComPPI
PAK2 LPXN 25348397 N/A physical interaction ComPPI
PAK2 USP47 25348397 N/A physical interaction ComPPI
PAK2 PPM1A 25348397 N/A physical interaction ComPPI
PAK2 MAPK14 25348397 N/A physical interaction ComPPI
PAK2 GSTM3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 UBE2V1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 SEPTIN2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PGRMC1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 SOD2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PSMA1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 CSDE1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PEBP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 CALR 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PPP2R2B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 BTF3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 GDI2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PSMB7 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 RPL24 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 APEX1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 ANXA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 EIF4E 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 TRIM28 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 CPSF6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PCMT1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 P4HB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 AHCY 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 ECHS1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 AK2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 NUDC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 ACP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 GANAB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PSMD13 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 EIF3I 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 PSMA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 RPL32 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 GOT2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 RPL23A 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 RAP1B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
PAK2 CTTN 18344974 24234451 25348397 phosphorylation reaction protein kinase assay ComPPI,IntAct
PAK2 TNK2 20696164 24234451 25348397 N/A solid phase assay ComPPI,IntAct
PAK2 CASP7 21555521 24234451 25348397 phosphorylation reaction,colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,protein kinase assay,confocal microscopy ComPPI,IntAct
PAK2 HTT 19240112 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation ComPPI,IntAct,OmniPath
PAK2 PKM 25348397 N/A protein kinase assay ComPPI
PAK2 PAK2 10075701 14525934 16837009 24234451 9786869 phosphorylation reaction,physical association cosedimentation in solution,experimental interaction detection,light scattering,protein kinase assay HPRD,IntAct
SRC PAK2 12215529 16374509 27898060 stimulant N/A OmniPath
PRKAA2 PAK2 22137581 26218748 27898060 N/A N/A OmniPath
PAK2 SYN1 10571231 12237306 27898060 N/A N/A OmniPath
PAK2 CTTN 12453877 18344974 27898060 stimulant N/A OmniPath
CTTN PAK2 12453877 18344974 27898060 N/A N/A OmniPath
MYC PAK2 14749374 16081735 27898060 N/A N/A OmniPath
PAK2 MYC 14749374 16081735 27898060 inhibition N/A OmniPath
PAK2 CASP7 21555521 27898060 inhibition N/A OmniPath
PAK2 MYL9 10047984 27898060 N/A N/A OmniPath
CASP3 PAK2 16204230 25241761 27898060 9171063 9786869 stimulant N/A OmniPath
PAK2 H4C1 16807684 17081983 18669648 19007248 19690332 21724829 27898060 N/A N/A OmniPath
HSPA5 PAK2 15908432 27898060 N/A N/A OmniPath
PPM1A PAK2 18586681 27898060 N/A N/A OmniPath
NCK1 PAK2 11160719 11278553 16374509 27898060 stimulant N/A OmniPath
PAK2 NCK1 11160719 11278553 16374509 27898060 N/A N/A OmniPath
PPM1F PAK2 20016286 27898060 inhibition N/A OmniPath
PAK2 MAP2K3 27898060 7499279 stimulant N/A OmniPath
RAC1 PAK2 19264842 20696164 20936779 22705156 27898060 9535855 9823899 stimulant N/A OmniPath
ABL1 PAK2 11121037 20841568 27898060 inhibition N/A OmniPath
PAK2 ABL1 11121037 18161990 20841568 27898060 inhibition,stimulant N/A OmniPath
PAK2 RAF1 10712905 16837009 1683701 27898060 stimulant N/A OmniPath
PAK2 EIF4G1 16281055 17353931 27898060 inhibition N/A OmniPath
PAK2 VIM 11895474 17287340 18212344 18578522 18669648 18767875 19007248 19651622 19664995 19691289 20058876 20068231 20166139 2500966 27898060 N/A N/A OmniPath
PAK2 ZFP36 16262601 27898060 N/A N/A OmniPath
CDC42 PAK2 10320322 16204230 17353931 20696164 20936779 25416956 27898060 7592896 9535855 9822598 9823899 stimulant N/A OmniPath
PAK2 RPS6 17287340 17322306 18669648 18767875 19007248 1985906 27898060 N/A N/A OmniPath
PAK2 JUN 21177766 27898060 stimulant N/A OmniPath
PAK2 MKNK1 15234964 25241761 27898060 inhibition,stimulant N/A OmniPath
PAK2 CALD1 16800003 27898060 N/A N/A OmniPath
PAK2 NF2 11703924 11719502 11782491 14724586 14981079 15378014 15743831 16267393 16652148 17175165 17566081 18071304 18835652 20178741 22516197 25925953 27898060 inhibition,stimulant N/A OmniPath
GZMM PAK2 19103589 27898060 N/A N/A OmniPath
ARHGEF6 PAK2 16374509 17392278 27898060 N/A N/A OmniPath
SYK PAK2 14673144 27898060 N/A N/A OmniPath
PRL PAK2 11943200 27898060 N/A N/A OmniPath
PAK2 PRL 11943200 15687336 19555049 27898060 stimulant N/A OmniPath
PAK2 MYLK 10748018 18088087 2160950 27898060 inhibition N/A OmniPath

Visualization