Gene Information gene info

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GENE：PAWR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PAWR
FullNmae pro-apoptotic WT1 regulator
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8614
EnsembleID ENSG00000177425
Uniprot Q96IZ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PAWR pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAWR apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PAWR apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PAWR GO:0000122,GO:0000785,GO:0003714,GO:0003779,GO:0005515,GO:0005634,GO:0005737,GO:0005737,GO:0005829,GO:0005884,GO:0005886,GO:0006915,GO:0010628,GO:0010629,GO:0015629,GO:0019899,GO:0030889,GO:0042130,GO:0042986,GO:0043065,GO:0043065,GO:0043522,GO:0048147,GO:0050860,GO:0051017,GO:0097190,GO:1901300,GO:2000774

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AKT1 PAWR 16209943 23180781 physical association anti tag coimmunoprecipitation InnateDB
PAWR PRKCZ 11755531 16209943 23180781 physical association anti tag coimmunoprecipitation InnateDB
SQSTM1 PAWR 11755531 23180781 physical association anti tag coimmunoprecipitation InnateDB
PAWR SQSTM1 11755531 23180781 physical association anti tag coimmunoprecipitation InnateDB
FAS PAWR 15993755 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
FOXP3 PAWR 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PAWR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 PAWR 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 PAWR 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000048B5E9 PAWR 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB PAWR 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 PAWR 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F PAWR 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 PAWR 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 PAWR 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF PAWR 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 PAWR 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000003BF62 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000272039 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000250A40 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000031D186 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000015F70F PAWR 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 PAWR 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F PAWR 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 PAWR 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 PAWR 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CSNK2A1 PAWR 22135298 phosphorylation N/A PhosphoSite
AATF PAWR 25361965 interaction type N/A PTMCode2
PAWR AATF 25361965 interaction type N/A PTMCode2
DAPK3 PAWR 25361965 interaction type N/A PTMCode2
PAWR DAPK3 25361965 interaction type N/A PTMCode2
PAWR TFPT 25361965 interaction type N/A PTMCode2
TFPT PAWR 25361965 interaction type N/A PTMCode2
PAWR PRKCZ 25361965 interaction type N/A PTMCode2
PRKCZ PAWR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TRIM21 PAWR 25348397 N/A physical interaction ComPPI
TFPT PAWR 14525934 16229834 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
VIM PAWR 24234451 25218743 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
STAT1 PAWR 25348397 N/A physical interaction ComPPI
GRB2 PAWR 12577067 24234451 25348397 association pull down ComPPI,IntAct
SFPQ PAWR 25348397 N/A physical interaction ComPPI
WT1 PAWR 14525934 25348397 8943350 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RRAS2 PAWR 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SNX2 PAWR 25348397 N/A physical interaction ComPPI
SNX6 PAWR 25348397 N/A physical interaction ComPPI
HSPA5 PAWR 14525934 19632185 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,fluorescence microscopy,in vitro,in vivo,confocal microscopy ComPPI,HPRD,IntAct
E2F1 PAWR 18660514 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation ComPPI,IntAct
RPA1 PAWR 25348397 N/A physical interaction ComPPI
HMG20A PAWR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKCZ PAWR 14525934 25348397 8797824 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CFTR PAWR 25348397 N/A physical interaction ComPPI
SQSTM1 PAWR 25348397 N/A physical interaction ComPPI
DAPK3 PAWR 10602480 12917339 14525934 24234451 25348397 physical association coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
PAWR PML 12717420 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PAWR THAP1 12717420 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
PAWR ATP5F1C 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PAWR SLC5A1 25348397 N/A physical interaction ComPPI
PAWR FBXO25 25348397 N/A physical interaction ComPPI
PAWR SPSB1 20561531 24234451 25348397 N/A isothermal titration calorimetry,x-ray crystallography,physical interaction ComPPI,IntAct
PAWR SPSB2 20561531 24234451 25348397 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct
PAWR SPSB4 20561531 24234451 25348397 N/A isothermal titration calorimetry,physical interaction ComPPI,IntAct
PAWR DRD2 16051151 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PAWR PAN2 25348397 N/A physical interaction ComPPI
PAWR CAND1 25348397 N/A physical interaction ComPPI
PAWR CARS1 25348397 N/A physical interaction ComPPI
PAWR NIBAN2 25348397 N/A physical interaction ComPPI
PAWR IDE 25348397 N/A physical interaction ComPPI
PAWR JMJD6 25348397 N/A physical interaction ComPPI
PAWR SHMT1 25348397 N/A physical interaction ComPPI
PAWR PPM1G 25348397 N/A physical interaction ComPPI
PAWR SHMT2 25348397 N/A physical interaction ComPPI
PAWR VPS29 25348397 N/A physical interaction ComPPI
PAWR FBXO45 25348397 N/A physical interaction ComPPI
PAWR CCDC8 25348397 N/A physical interaction ComPPI
PAWR EED 25348397 N/A physical interaction ComPPI
PAWR LUZP4 25348397 N/A physical interaction ComPPI
PAWR DDX39A 25348397 N/A physical interaction ComPPI
PAWR CEP290 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PAWR CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PAWR MYH9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAWR IKBIP 25348397 N/A physical interaction ComPPI
PAWR SCOC 25348397 N/A physical interaction ComPPI
PAWR SLC25A41 25348397 N/A physical interaction ComPPI
PAWR G3BP1 25348397 N/A physical interaction ComPPI
PAWR HDAC6 25348397 N/A physical interaction ComPPI
PAWR PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
AATF PAWR 14525934 14627703 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
H3-3A PAWR 25348397 N/A physical interaction ComPPI
APEH PAWR 25348397 N/A physical interaction ComPPI
ATP6V1C1 PAWR 25348397 N/A physical interaction ComPPI
PAWR PAWR 11382383 14525934 15090548 N/A experimental interaction detection HPRD
SLC5A7 PAWR 14525934 15090548 N/A experimental interaction detection HPRD
PAWR DIABLO 18660514 24234451 physical association chromatin immunoprecipitation assay IntAct
PAWR AKT1 16209943 27898060 N/A N/A OmniPath
PRKCZ PAWR 11755531 16209943 27898060 8797824 N/A N/A OmniPath
PAWR WT1 27898060 8943350 inhibition N/A OmniPath

Visualization










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