GENE:PDCD10
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | PDCD10 |
FullNmae | programmed cell death 10 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:8761 |
EnsembleID | ENSG00000114209 |
Uniprot | Q9BUL8 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
PDCD10 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PDCD10 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PDCD10 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
PDCD10 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
PDCD10 | GO:0000139,GO:0001525,GO:0003158,GO:0005515,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0008284,GO:0010628,GO:0010629,GO:0019901,GO:0030335,GO:0030335,GO:0031098,GO:0032874,GO:0033138,GO:0036481,GO:0042803,GO:0043066,GO:0043406,GO:0043406,GO:0044319,GO:0045747,GO:0045765,GO:0050821,GO:0051683,GO:0070062,GO:0071902,GO:0090051,GO:0090168,GO:0090316,GO:0090443,GO:1903358,GO:1903588,GO:1990830 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
PDCD10 | hsa:11235 | path:hsa04520 | Adherens junction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
E2F4 | PDCD10 | 17531812 18971253 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
ETS1 | PDCD10 | 20019798 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | PDCD10 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
RUNX1 | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | PDCD10 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MYC | PDCD10 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000338542 | PDCD10 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS00002152A8 | PDCD10 | 20371350 21572407 25416803 | mrna cleavage,inhibition | nucleotide sequence identification,clip | TarBase |
URS0000065D58 | PDCD10 | 18668040 21572407 25416803 | mrna cleavage,inhibition | experimental interaction detection,clip | TarBase |
URS0000324096 | PDCD10 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
URS0000427B68 | PDCD10 | 21572407 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004719AB | PDCD10 | 21572407 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000003ABC4 | PDCD10 | 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000085F64 | PDCD10 | 21572407 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000076B539 | PDCD10 | 21572407 23446348 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000237AF9 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000040EC3B | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004CCA62 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000027080C | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00003E6EFA | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004AF715 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004DA9DB | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000CBE63 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000021D7C8 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002CF3F0 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000005CF5F | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001DE669 | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002FAA8C | PDCD10 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000048BA36 | PDCD10 | 25416803 26647742 27132035 | mrna cleavage,inhibition | western blot,miRNA interference luciferase reporter assay | TarBase |
URS0000302909 | PDCD10 | 25416803 26707063 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
URS0000171525 | PDCD10 | 25416803 26400441 | mrna cleavage,inhibition | array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
STK25 | PDCD10 | 22135298 | phosphorylation | N/A | PhosphoSite |
STK26 | PDCD10 | 22135298 | phosphorylation | N/A | PhosphoSite |
FGFR1OP2 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | FGFR1OP2 | 25361965 | interaction type | N/A | PTMCode2 |
CTTNBP2NL | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | CTTNBP2NL | 25361965 | interaction type | N/A | PTMCode2 |
PPP2R1A | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | PPP2R1A | 25361965 | interaction type | N/A | PTMCode2 |
PPP2R1B | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | PPP2R1B | 25361965 | interaction type | N/A | PTMCode2 |
PPM1A | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | PPM1A | 25361965 | interaction type | N/A | PTMCode2 |
ANKHD1 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | ANKHD1 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | STRN3 | 25361965 | interaction type | N/A | PTMCode2 |
STRN3 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | CCM2 | 25361965 | interaction type | N/A | PTMCode2 |
CCM2 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | STRN4 | 25361965 | interaction type | N/A | PTMCode2 |
STRN4 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | STK3 | 25361965 | interaction type | N/A | PTMCode2 |
STK3 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | PPP2CA | 25361965 | interaction type | N/A | PTMCode2 |
PPP2CA | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
CTTNBP2 | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | CTTNBP2 | 25361965 | interaction type | N/A | PTMCode2 |
SLMAP | PDCD10 | 25361965 | interaction type | N/A | PTMCode2 |
PDCD10 | SLMAP | 25361965 | interaction type | N/A | PTMCode2 |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
PDCD10 | C4ORF19 | 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
PDCD10 | STK25 | 14525934 16189514 17657516 18782753 21516116 23455922 23665169 24234451 25348397 25416956 | phosphorylation reaction,association,physical association | anti tag coimmunoprecipitation,two hybrid,cosedimentation in solution,molecular sieving,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,protein kinase assay,tandem affinity purification,surface plasmon resonance array,two hybrid prey pooling approach,validated two hybrid,two hybrid | ComPPI,HPRD,IntAct |
PDCD10 | STK24 | 14525934 16189514 17353931 17657516 18782753 21516116 23455922 23541896 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,tandem affinity purification,bio-layer interferometry,two hybrid | ComPPI,HPRD,IntAct |
PDCD10 | CHMP5 | 14525934 16730941 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
PDCD10 | MCC | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | CTTNBP2 | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | CTTNBP2NL | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | STRIP1 | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | MOB4 | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | PPP2R1A | 18782753 24234451 25348397 28330616 | association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
PDCD10 | PPP2CA | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | STRN | 18782753 24234451 24366813 25348397 26496610 | association,physical association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | STRN3 | 18782753 24234451 24366813 25348397 26496610 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | STK26 | 18782753 23455922 24234451 25348397 | association,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,tandem affinity purification,surface plasmon resonance array,bio-layer interferometry,two hybrid prey pooling approach | ComPPI,IntAct |
PDCD10 | PPP2R1B | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | STRN4 | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | SIKE1 | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | SLMAP | 18782753 24234451 24366813 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | FGFR1OP2 | 18782753 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | TRAF3IP3 | 18782753 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | VCP | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | FN1 | 19738201 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
PDCD10 | VCAM1 | 19738201 22623428 24234451 25348397 | association | cross-linking study,physical interaction | ComPPI,IntAct |
PDCD10 | ITGA4 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | CLNS1A | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | CNN2 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | EHD1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | EZR | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | HK1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | NOL3 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | PCNA | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | ALDH1B1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | DCPS | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | ERP44 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | FERMT2 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | FKBP9 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | HEXA | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | HEXB | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | NUDCD1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | PFAS | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | SGTA | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | TATDN1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | UBR7 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | VCL | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | ATP6V1C2 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | UNK | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | CTPS1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | HNRNPF | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | ATP6V1A | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | PPME1 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | PPP2CB | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PDCD10 | PROSER2 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | BMP7 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | GTF2E2 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | SNRNP27 | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | FAM174A | 25348397 | N/A | physical interaction | ComPPI |
PDCD10 | CCM2 | 17657516 23266514 24234451 25348397 27898060 | colocalization,physical association | anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy | ComPPI,IntAct,OmniPath |
PDCD10 | PTPN13 | 17657516 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,two hybrid,pull down | ComPPI,IntAct |
PDCD10 | KRIT1 | 17657516 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
PDCD10 | FARSA | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
PDCD10 | FAM118B | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
PDCD10 | PLEKHS1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
PDCD10 | MINAR1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
PDCD10 | KSR1 | 24234451 25348397 27086506 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
PDCD10 | PDCD10 | 23665169 24234451 | N/A | cosedimentation in solution | IntAct |
METTL14 | PDCD10 | 24234451 29507755 | association | anti tag coimmunoprecipitation | IntAct |
PTPN13 | PDCD10 | 17657516 27898060 | inhibition | N/A | OmniPath |
STK26 | PDCD10 | 18782753 19370760 23455922 23541896 23665169 25416956 26344197 27898060 | N/A | N/A | OmniPath |