Gene Information gene info

GENE:PDCD10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PDCD10
FullNmae programmed cell death 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8761
EnsembleID ENSG00000114209
Uniprot Q9BUL8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PDCD10 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PDCD10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PDCD10 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PDCD10 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PDCD10 GO:0000139,GO:0001525,GO:0003158,GO:0005515,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0008284,GO:0010628,GO:0010629,GO:0019901,GO:0030335,GO:0030335,GO:0031098,GO:0032874,GO:0033138,GO:0036481,GO:0042803,GO:0043066,GO:0043406,GO:0043406,GO:0044319,GO:0045747,GO:0045765,GO:0050821,GO:0051683,GO:0070062,GO:0071902,GO:0090051,GO:0090168,GO:0090316,GO:0090443,GO:1903358,GO:1903588,GO:1990830

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PDCD10 hsa:11235 path:hsa04520 Adherens junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF8 PDCD10 19801548 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PDCD10 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 PDCD10 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PDCD10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PDCD10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC PDCD10 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PDCD10 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002152A8 PDCD10 20371350 21572407 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS0000065D58 PDCD10 18668040 21572407 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS0000324096 PDCD10 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000427B68 PDCD10 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PDCD10 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 PDCD10 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 PDCD10 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 PDCD10 21572407 23446348 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000237AF9 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EC3B PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003E6EFA PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FAA8C PDCD10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 PDCD10 25416803 26647742 27132035 mrna cleavage,inhibition western blot,miRNA interference luciferase reporter assay TarBase
URS0000302909 PDCD10 25416803 26707063 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000171525 PDCD10 25416803 26400441 mrna cleavage,inhibition array technology,western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
STK25 PDCD10 22135298 phosphorylation N/A PhosphoSite
STK26 PDCD10 22135298 phosphorylation N/A PhosphoSite
FGFR1OP2 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 FGFR1OP2 25361965 interaction type N/A PTMCode2
CTTNBP2NL PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 CTTNBP2NL 25361965 interaction type N/A PTMCode2
PPP2R1A PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 PPP2R1A 25361965 interaction type N/A PTMCode2
PPP2R1B PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 PPP2R1B 25361965 interaction type N/A PTMCode2
PPM1A PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 PPM1A 25361965 interaction type N/A PTMCode2
ANKHD1 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 ANKHD1 25361965 interaction type N/A PTMCode2
PDCD10 STRN3 25361965 interaction type N/A PTMCode2
STRN3 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 CCM2 25361965 interaction type N/A PTMCode2
CCM2 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 STRN4 25361965 interaction type N/A PTMCode2
STRN4 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 STK3 25361965 interaction type N/A PTMCode2
STK3 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 PPP2CA 25361965 interaction type N/A PTMCode2
PPP2CA PDCD10 25361965 interaction type N/A PTMCode2
CTTNBP2 PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 CTTNBP2 25361965 interaction type N/A PTMCode2
SLMAP PDCD10 25361965 interaction type N/A PTMCode2
PDCD10 SLMAP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PDCD10 C4ORF19 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PDCD10 STK25 14525934 16189514 17657516 18782753 21516116 23455922 23665169 24234451 25348397 25416956 phosphorylation reaction,association,physical association anti tag coimmunoprecipitation,two hybrid,cosedimentation in solution,molecular sieving,pull down,surface plasmon resonance,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,protein kinase assay,tandem affinity purification,surface plasmon resonance array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
PDCD10 STK24 14525934 16189514 17353931 17657516 18782753 21516116 23455922 23541896 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,tandem affinity purification,bio-layer interferometry,two hybrid ComPPI,HPRD,IntAct
PDCD10 CHMP5 14525934 16730941 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
PDCD10 MCC 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 CTTNBP2 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 CTTNBP2NL 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 STRIP1 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 MOB4 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 PPP2R1A 18782753 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PDCD10 PPP2CA 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 STRN 18782753 24234451 24366813 25348397 26496610 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 STRN3 18782753 24234451 24366813 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 STK26 18782753 23455922 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,tandem affinity purification,surface plasmon resonance array,bio-layer interferometry,two hybrid prey pooling approach ComPPI,IntAct
PDCD10 PPP2R1B 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 STRN4 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 SIKE1 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 SLMAP 18782753 24234451 24366813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 FGFR1OP2 18782753 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 TRAF3IP3 18782753 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 VCP 25348397 N/A physical interaction ComPPI
PDCD10 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PDCD10 VCAM1 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
PDCD10 ITGA4 25348397 N/A physical interaction ComPPI
PDCD10 CLNS1A 25348397 N/A physical interaction ComPPI
PDCD10 CNN2 25348397 N/A physical interaction ComPPI
PDCD10 EHD1 25348397 N/A physical interaction ComPPI
PDCD10 EZR 25348397 N/A physical interaction ComPPI
PDCD10 HK1 25348397 N/A physical interaction ComPPI
PDCD10 NOL3 25348397 N/A physical interaction ComPPI
PDCD10 PCNA 25348397 N/A physical interaction ComPPI
PDCD10 ALDH1B1 25348397 N/A physical interaction ComPPI
PDCD10 DCPS 25348397 N/A physical interaction ComPPI
PDCD10 ERP44 25348397 N/A physical interaction ComPPI
PDCD10 FERMT2 25348397 N/A physical interaction ComPPI
PDCD10 FKBP9 25348397 N/A physical interaction ComPPI
PDCD10 HEXA 25348397 N/A physical interaction ComPPI
PDCD10 HEXB 25348397 N/A physical interaction ComPPI
PDCD10 NUDCD1 25348397 N/A physical interaction ComPPI
PDCD10 PFAS 25348397 N/A physical interaction ComPPI
PDCD10 SGTA 25348397 N/A physical interaction ComPPI
PDCD10 TATDN1 25348397 N/A physical interaction ComPPI
PDCD10 UBR7 25348397 N/A physical interaction ComPPI
PDCD10 VCL 25348397 N/A physical interaction ComPPI
PDCD10 ATP6V1C2 25348397 N/A physical interaction ComPPI
PDCD10 UNK 25348397 N/A physical interaction ComPPI
PDCD10 CTPS1 25348397 N/A physical interaction ComPPI
PDCD10 HNRNPF 25348397 N/A physical interaction ComPPI
PDCD10 ATP6V1A 25348397 N/A physical interaction ComPPI
PDCD10 PPME1 25348397 N/A physical interaction ComPPI
PDCD10 PPP2CB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PDCD10 PROSER2 25348397 N/A physical interaction ComPPI
PDCD10 BMP7 25348397 N/A physical interaction ComPPI
PDCD10 GTF2E2 25348397 N/A physical interaction ComPPI
PDCD10 SNRNP27 25348397 N/A physical interaction ComPPI
PDCD10 FAM174A 25348397 N/A physical interaction ComPPI
PDCD10 CCM2 17657516 23266514 24234451 25348397 27898060 colocalization,physical association anti tag coimmunoprecipitation,pull down,physical interaction,confocal microscopy ComPPI,IntAct,OmniPath
PDCD10 PTPN13 17657516 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,pull down ComPPI,IntAct
PDCD10 KRIT1 17657516 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDCD10 FARSA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDCD10 FAM118B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDCD10 PLEKHS1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDCD10 MINAR1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PDCD10 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
PDCD10 PDCD10 23665169 24234451 N/A cosedimentation in solution IntAct
METTL14 PDCD10 24234451 29507755 association anti tag coimmunoprecipitation IntAct
PTPN13 PDCD10 17657516 27898060 inhibition N/A OmniPath
STK26 PDCD10 18782753 19370760 23455922 23541896 23665169 25416956 26344197 27898060 N/A N/A OmniPath

Visualization