Gene Information gene info

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GENE：PHIP

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHIP
FullNmae pleckstrin homology domain interacting protein
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15673
EnsembleID ENSG00000146247
Uniprot Q8WWQ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHIP pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHIP mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHIP apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHIP apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PHIP GO:0001932,GO:0005158,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0006357,GO:0007010,GO:0007010,GO:0008284,GO:0008286,GO:0008360,GO:0022604,GO:0043066,GO:0043568,GO:0045840,GO:0045893,GO:0045944,GO:0070577,GO:2001237

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PHIP 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PHIP 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PHIP 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PHIP 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D PHIP 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS0000512C88 PHIP 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003A5E54 PHIP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 PHIP 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 PHIP 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 PHIP 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC PHIP 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PHIP 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 PHIP 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 PHIP 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 PHIP 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000042B108 PHIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E PHIP 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 PHIP 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000CBE63 PHIP 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FF522 PHIP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00005E6F45 PHIP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000195F5B PHIP 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000008C563 PHIP 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PHIP DDB1 25361965 interaction type N/A PTMCode2
DDB1 PHIP 25361965 interaction type N/A PTMCode2
PHIP IRS1 25361965 interaction type N/A PTMCode2
IRS1 PHIP 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ORC1 PHIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DCUN1D1 PHIP 25348397 N/A physical interaction ComPPI
RPL10 PHIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 PHIP 25348397 N/A physical interaction ComPPI
TMPO PHIP 25348397 N/A physical interaction ComPPI
CUL4B PHIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MPHOSPH8 PHIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL4A PHIP 25348397 N/A physical interaction ComPPI
IRS1 PHIP 11018022 25348397 27898060 N/A two hybrid,in vitro,in vivo ComPPI,OmniPath
NR4A1 PHIP 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RNF2 PHIP 25348397 N/A physical interaction ComPPI
CUL7 PHIP 25348397 N/A physical interaction ComPPI
H3C1 PHIP 25348397 N/A physical interaction ComPPI
HDAC11 PHIP 23752268 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TUBB4A PHIP 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
DDB1 PHIP 25348397 N/A physical interaction ComPPI
EGR1 PHIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IFI16 PHIP 25348397 N/A physical interaction ComPPI
CNTROB PHIP 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CENPA PHIP 25348397 N/A physical interaction ComPPI
TUBB3 PHIP 25348397 N/A two hybrid,physical interaction ComPPI
SIRT7 PHIP 25348397 N/A physical interaction ComPPI
STMN4 PHIP 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PHIP MC1R 25348397 N/A physical interaction ComPPI
PHIP OBSL1 25348397 N/A physical interaction ComPPI
PHIP SPICE1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PHIP TMPO 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHIP UBXN7 25348397 N/A physical interaction ComPPI
PHIP PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
HNRNPCL2 PHIP 24234451 30021884 physical association cross-linking study IntAct
TPR PHIP 24234451 30021884 physical association cross-linking study IntAct
LMNA PHIP 24234451 30021884 physical association cross-linking study IntAct
HSPA5 PHIP 24234451 30021884 physical association cross-linking study IntAct

Visualization










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