Gene Information gene info

GENE:PIH1D1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PIH1D1
FullNmae PIH1 domain containing 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26075
EnsembleID ENSG00000104872
Uniprot Q9NWS0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PIH1D1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PIH1D1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PIH1D1 GO:0000492,GO:0000492,GO:0005515,GO:0005634,GO:0005730,GO:0005737,GO:0005737,GO:0006338,GO:0006364,GO:0019901,GO:0030855,GO:0042393,GO:0048254,GO:0050821,GO:0051117,GO:0051219,GO:0070761,GO:0071902,GO:0097255,GO:0097255,GO:0097255,GO:0140566,GO:1901838,GO:1901838,GO:1902661,GO:1904263,GO:1905669,GO:1990062,GO:1990904,GO:2001268

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PIH1D1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PIH1D1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PIH1D1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PIH1D1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A PIH1D1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 PIH1D1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CTCF PIH1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PIH1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PIH1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PIH1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PIH1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PIH1D1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PIH1D1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 PIH1D1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase

Source Target Pmid Interactiontype Methods Database
RPAP3 PIH1D1 25361965 interaction type N/A PTMCode2
PIH1D1 RPAP3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MFAP1 PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEM PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BYSL PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBPMS PIH1D1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
FAM90A1 PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLR2L PIH1D1 25348397 N/A physical interaction ComPPI
PPP1CC PIH1D1 24234451 24366813 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COIL PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
UXT PIH1D1 25348397 N/A physical interaction ComPPI
TYK2 PIH1D1 25348397 N/A physical interaction ComPPI
PPP1CB PIH1D1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMARCD1 PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF5B PIH1D1 24234451 24656813 25348397 physical association pull down ComPPI,IntAct
DOCK7 PIH1D1 25348397 N/A physical interaction ComPPI
HSP90AA1 PIH1D1 25348397 N/A physical interaction ComPPI
PPP1R3A PIH1D1 25348397 N/A physical interaction ComPPI
RUVBL1 PIH1D1 20371770 24234451 24656813 25348397 26711270 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
PPP1CA PIH1D1 24234451 25348397 27173435 28330616 association,physical association pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification,inference by socio-affinity scoring ComPPI,IntAct
KSR2 PIH1D1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
AKAP2 PIH1D1 25348397 N/A physical interaction ComPPI
UBR5 PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NPHP1 PIH1D1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MAPK6 PIH1D1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PARD6A PIH1D1 14676191 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 PIH1D1 25348397 N/A physical interaction ComPPI
POLR3E PIH1D1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR3D PIH1D1 25348397 N/A physical interaction ComPPI
URI1 PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2E PIH1D1 25348397 N/A physical interaction ComPPI
POLR2A PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TSC1 PIH1D1 25348397 N/A physical interaction ComPPI
STK4 PIH1D1 23386615 24234451 25348397 physical association two hybrid ComPPI,IntAct
RPL7 PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
GPN1 PIH1D1 25348397 N/A physical interaction ComPPI
PSMD4 PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CA4 PIH1D1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EAF1 PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTOR PIH1D1 24036451 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
MAP3K3 PIH1D1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
POLR2J PIH1D1 25348397 N/A physical interaction ComPPI
POLR1A PIH1D1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPEF2 PIH1D1 25348397 N/A physical interaction ComPPI
TSC22D4 PIH1D1 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
POLR3A PIH1D1 25348397 N/A physical interaction ComPPI
PNISR PIH1D1 24234451 24656813 25348397 physical association pull down ComPPI,IntAct
EFTUD2 PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR2F PIH1D1 25348397 N/A physical interaction ComPPI
POLR2C PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2G PIH1D1 25348397 N/A physical interaction ComPPI
TRIP12 PIH1D1 24234451 24656813 25348397 physical association pull down ComPPI,IntAct
RPTOR PIH1D1 24036451 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
NPHP4 PIH1D1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RUVBL2 PIH1D1 24234451 24656813 25348397 26711270 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
POLR2D PIH1D1 25348397 N/A physical interaction ComPPI
POLR2B PIH1D1 25348397 N/A physical interaction ComPPI
POLR2I PIH1D1 25348397 N/A physical interaction ComPPI
DCAF6 PIH1D1 25348397 N/A physical interaction ComPPI
NEK8 PIH1D1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KMT2A PIH1D1 25348397 N/A physical interaction ComPPI
CCDC88A PIH1D1 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SCNM1 PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SEPTIN1 PIH1D1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIH1D1 RPAP2 24234451 24656813 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIH1D1 RPAP3 24234451 24656813 25036637 25348397 26711270 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIH1D1 TTI1 20371770 20801936 24234451 25348397 association pull down,physical interaction,tandem affinity purification ComPPI,IntAct
PIH1D1 TTI2 20801936 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
PIH1D1 FBL 25348397 N/A physical interaction ComPPI
PIH1D1 HSP90AA2P 25348397 N/A physical interaction ComPPI
PIH1D1 TELO2 24234451 24656813 25348397 association,physical association anti tag coimmunoprecipitation,isothermal titration calorimetry,peptide array,pull down,x-ray crystallography,physical interaction ComPPI,IntAct
PIH1D1 NXF1 25348397 N/A physical interaction ComPPI
PIH1D1 IFT122 25348397 N/A physical interaction ComPPI
PIH1D1 GPN3 25348397 N/A physical interaction ComPPI
PIH1D1 PDRG1 25348397 N/A physical interaction ComPPI
PIH1D1 MYZAP 25348397 N/A physical interaction ComPPI
PIH1D1 POLR2M 24234451 24656813 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIH1D1 POLR3B 25348397 N/A physical interaction ComPPI
PIH1D1 DNAAF10 25348397 N/A physical interaction ComPPI
PIH1D1 LRCH3 25348397 N/A physical interaction ComPPI
PIH1D1 POLR3K 25348397 N/A physical interaction ComPPI
PIH1D1 SUPT6H 25348397 N/A physical interaction ComPPI
PIH1D1 OFD1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PIH1D1 MKS1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
PIH1D1 SEC16A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIH1D1 ECD 24234451 24656813 25348397 26711270 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,isothermal titration calorimetry,pull down,physical interaction ComPPI,IntAct
PIH1D1 CRBN 25348397 N/A physical interaction ComPPI
PIH1D1 ASB7 25348397 N/A physical interaction ComPPI
PIH1D1 TPTE 25348397 N/A physical interaction ComPPI
PIH1D1 PPP1R7 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
PIH1D1 ZNHIT2 25348397 N/A physical interaction ComPPI
PIH1D1 NOP58 17636026 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PIH1D1 MPHOSPH9 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PIH1D1 PHF8 24234451 24656813 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PIH1D1 MISP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIH1D1 CDCA7L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIH1D1 FARP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIH1D1 TNS4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PIH1D1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization