GENE：POU4F1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | POU4F1 |
| FullNmae | POU class 4 homeobox 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:9218 |
| EnsembleID | ENSG00000152192 |
| Uniprot | Q01851 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| POU4F1 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| POU4F1 | apoptosis | 36341760 | The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. | regulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| POU4F1 | GO:0000122,GO:0000785,GO:0000978,GO:0000978,GO:0000981,GO:0000981,GO:0000981,GO:0000981,GO:0001227,GO:0001228,GO:0001764,GO:0001967,GO:0003223,GO:0003682,GO:0003697,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0006357,GO:0007409,GO:0007416,GO:0007498,GO:0007507,GO:0010628,GO:0010629,GO:0021535,GO:0021559,GO:0021953,GO:0021986,GO:0031175,GO:0043005,GO:0043066,GO:0043069,GO:0043524,GO:0043524,GO:0043525,GO:0043565,GO:0045672,GO:0045944,GO:0048665,GO:0048880,GO:0048935,GO:0050767,GO:0051020,GO:0051090,GO:0051355,GO:0051402,GO:0051726,GO:0060384,GO:0061629,GO:0071345,GO:0071392,GO:0072332,GO:0090575,GO:1990837,GO:2000679 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CTCF | POU4F1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | POU4F1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | POU4F1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | POU4F1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | POU4F1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | POU4F1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EWSR1 | POU4F1 | 15021903 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ERG | POU4F1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FLI1 | POU4F1 | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000003ABC4 | POU4F1 | 19088304 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002152A8 | POU4F1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00004F2EB0 | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000366551 | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000027352D | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AD450 | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00002198F3 | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065FDF | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000041FA2C | POU4F1 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| EWSR1 | POU4F1 | 12432261 14525934 25348397 27898060 | N/A | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,OmniPath |
| RIT2 | POU4F1 | 12934100 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid | ComPPI,HPRD |
| ESR1 | POU4F1 | 14525934 25348397 9448000 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| POU4F1 | MAPRE3 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| POU4F1 | ESR1 | 27898060 9448000 | stimulant | N/A | OmniPath |
| RIT2 | POU4F1 | 12934100 27898060 | stimulant | N/A | OmniPath |