Gene Information gene info

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GENE：PTGIS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTGIS
FullNmae prostaglandin I2 synthase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9603
EnsembleID ENSG00000124212
Uniprot Q16647

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTGIS apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTGIS apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PTGIS GO:0001516,GO:0001516,GO:0004497,GO:0005506,GO:0005515,GO:0005615,GO:0005634,GO:0005783,GO:0005789,GO:0005789,GO:0005901,GO:0006690,GO:0006690,GO:0008116,GO:0008116,GO:0008116,GO:0016705,GO:0019371,GO:0020037,GO:0032088,GO:0034356,GO:0035360,GO:0045019,GO:0045766,GO:0050728,GO:0071347,GO:0071354,GO:0071456,GO:0097190,GO:0106256,GO:1900119

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTGIS hsa:5740 path:hsa00590 Arachidonic acid metabolism - Homo sapiens (human)
PTGIS hsa:5740 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR PTGIS 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 PTGIS 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PTGIS 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PTGIS 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PTGIS 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTGIS 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003BF62 PTGIS 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000E7139 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040FA88 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004E78D3 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000365675 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000148B91 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 PTGIS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000055929F PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 PTGIS 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 PTGIS 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF PTGIS 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PTGIS 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000279B6F PTGIS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000007FBA PTGIS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015A0D9 PTGIS 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000078918 PTGIS 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAV1 PTGIS 11339822 25348397 27898060 N/A physical interaction ComPPI,OmniPath
PTGS2 PTGIS 25348397 N/A physical interaction ComPPI
APP PTGIS 25348397 N/A physical interaction ComPPI
PTGIS KDM5B 24234451 24937458 association chromatin immunoprecipitation assay IntAct
VIM PTGIS 24234451 30021884 physical association cross-linking study IntAct

Visualization










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