Gene Information gene info

GENE:PTH

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTH
FullNmae parathyroid hormone
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9606
EnsembleID ENSG00000152266
Uniprot P01270

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTH pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTH autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTH apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTH apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
PTH GO:0001501,GO:0005179,GO:0005179,GO:0005515,GO:0005515,GO:0005576,GO:0005576,GO:0005615,GO:0006366,GO:0006874,GO:0007186,GO:0007189,GO:0007189,GO:0007202,GO:0007266,GO:0007267,GO:0008628,GO:0009059,GO:0009410,GO:0009967,GO:0010288,GO:0010468,GO:0010628,GO:0010629,GO:0010960,GO:0030282,GO:0030501,GO:0031856,GO:0031857,GO:0032331,GO:0033280,GO:0045453,GO:0045471,GO:0045725,GO:0045944,GO:0046058,GO:0046326,GO:0046686,GO:0048018,GO:0048873,GO:0051428,GO:0051428,GO:0055062,GO:0060732,GO:0071107,GO:0071774,GO:0071864,GO:0071866,GO:0090290,GO:1900158

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTH hsa:5741 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
PTH hsa:5741 path:hsa04928 Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)
PTH hsa:5741 path:hsa04961 Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human)
PTH hsa:5741 path:hsa05323 Rheumatoid arthritis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTCF PTH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTH 18971253 trascriptional regulation,stimulation inferred by curator TFlink
APEX1 PTH 14633989 trascriptional regulation,stimulation inferred by curator TFlink
GCM2 PTH 20558332 trascriptional regulation,stimulation inferred by curator TFlink
RUNX2 PTH 11814673 trascriptional regulation,stimulation inferred by curator TFlink
VDR PTH 17095575 7489414 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 PTH N/A trascriptional regulation,stimulation inferred by curator TFlink
SP1 PTH N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 PTH 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PTH PTH1R 25361965 interaction type N/A PTMCode2
PTH1R PTH 25361965 interaction type N/A PTMCode2
PTH2R PTH 25361965 interaction type N/A PTMCode2
PTH PTH2R 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
FEZ1 PTH 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTH1R PTH 14525934 25348397 9108031 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTH MEP1A 11278902 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
PTH BAG6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PTH ARFGEF3 25348397 N/A physical interaction ComPPI
PTH2R PTH 14525934 25348397 9482662 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
PTH PTH 10837469 14525934 N/A experimental interaction detection HPRD
PTH PTH1R 18981475 27898060 9108031 stimulant N/A OmniPath
PTH PTH2R 11861531 27898060 7797535 9482662 stimulant N/A OmniPath

Visualization