Gene Information gene info

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GENE：PTPMT1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPMT1
FullNmae protein tyrosine phosphatase mitochondrial 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26965
EnsembleID ENSG00000110536
Uniprot Q8WUK0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPMT1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPMT1 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PTPMT1 apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
PTPMT1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
PTPMT1 GO:0004439,GO:0004725,GO:0005515,GO:0005634,GO:0005739,GO:0005739,GO:0005743,GO:0008138,GO:0008962,GO:0008962,GO:0016311,GO:0017018,GO:0032049,GO:2001242

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 PTPMT1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 PTPMT1 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000EC1BE PTPMT1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PTPMT1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
KRTAP9-2 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CHCHD2 PTPMT1 25348397 N/A physical interaction ComPPI
ATP5PO PTPMT1 25348397 N/A physical interaction ComPPI
KRTAP5-9 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP10-8 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP4-12 PTPMT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNAP29 PTPMT1 25348397 N/A physical interaction ComPPI
KRTAP10-7 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT31 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COX5A PTPMT1 25348397 N/A physical interaction ComPPI
KRT40 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CYCS PTPMT1 25348397 N/A physical interaction ComPPI
MDFI PTPMT1 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PAK5 PTPMT1 25348397 N/A physical interaction ComPPI
COPS5 PTPMT1 25348397 N/A physical interaction ComPPI
GRN PTPMT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SIAH1 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
POLDIP2 PTPMT1 25348397 N/A physical interaction ComPPI
C1QBP PTPMT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MAPK6 PTPMT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UQCRC2 PTPMT1 25348397 N/A physical interaction ComPPI
ATP2A2 PTPMT1 25348397 N/A physical interaction ComPPI
SLC16A1 PTPMT1 25348397 N/A physical interaction ComPPI
FKBP8 PTPMT1 25348397 N/A physical interaction ComPPI
XPO4 PTPMT1 25348397 N/A physical interaction ComPPI
IMMT PTPMT1 25348397 N/A physical interaction ComPPI
CD79A PTPMT1 25348397 N/A physical interaction ComPPI
NUP133 PTPMT1 25348397 N/A physical interaction ComPPI
CLPX PTPMT1 25348397 N/A physical interaction ComPPI
TRIM27 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DUSP6 PTPMT1 25348397 N/A physical interaction ComPPI
RGS20 PTPMT1 25348397 N/A physical interaction ComPPI
TIMM50 PTPMT1 25348397 N/A physical interaction ComPPI
SLC25A10 PTPMT1 25348397 N/A physical interaction ComPPI
ATP5F1C PTPMT1 25348397 N/A physical interaction ComPPI
UQCRB PTPMT1 25348397 N/A physical interaction ComPPI
ECH1 PTPMT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MTUS2 PTPMT1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SLC25A3 PTPMT1 25348397 N/A physical interaction ComPPI
STOML2 PTPMT1 25348397 N/A physical interaction ComPPI
UQCRFS1 PTPMT1 25348397 N/A physical interaction ComPPI
NIPSNAP1 PTPMT1 25348397 N/A physical interaction ComPPI
MRPL12 PTPMT1 25348397 N/A physical interaction ComPPI
AFG3L2 PTPMT1 25348397 N/A physical interaction ComPPI
ATP5PD PTPMT1 25348397 N/A physical interaction ComPPI
GLS PTPMT1 25348397 N/A physical interaction ComPPI
FBXO6 PTPMT1 25348397 N/A physical interaction ComPPI
ATP5MK PTPMT1 25348397 N/A physical interaction ComPPI
IL13RA2 PTPMT1 25348397 N/A physical interaction ComPPI
BSG PTPMT1 25348397 N/A physical interaction ComPPI
ATAD3A PTPMT1 25348397 N/A physical interaction ComPPI
ATP5PB PTPMT1 25348397 N/A physical interaction ComPPI
SFXN1 PTPMT1 25348397 N/A physical interaction ComPPI
COX6B1 PTPMT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TAB1 PTPMT1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
OXA1L PTPMT1 25348397 N/A physical interaction ComPPI
NDUFS3 PTPMT1 25348397 N/A physical interaction ComPPI
NDUFA8 PTPMT1 25348397 N/A physical interaction ComPPI
LETM1 PTPMT1 25348397 N/A physical interaction ComPPI
ACSL4 PTPMT1 25348397 N/A physical interaction ComPPI
PTPMT1 KRTAP10-3 25348397 N/A physical interaction ComPPI
PTPMT1 CISD1 25348397 N/A physical interaction ComPPI
PTPMT1 NDUFAF2 25348397 N/A physical interaction ComPPI
PTPMT1 OXCT1 24234451 25348397 27499296 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PTPMT1 SLC18A1 25348397 N/A physical interaction ComPPI
PTPMT1 KRTAP10-9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MKI67 PTPMT1 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization










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